(Q34722386)

4 August 2017

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title

FMR1 silencing and the signals to chromatin: a unified model of transcriptional regulation (English)

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4 August 2017

Assam El-Osta

1

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PubMed ID

12099676

4 August 2017

language of work or name

English

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publication date

1 July 2002

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Biochemical and Biophysical Research Communications

4 August 2017

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4 August 2017

295

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4 August 2017

3

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4 August 2017

575-581

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

4 August 2017

1 reference

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

FMR1 protein: conserved RNP family domains and selective RNA binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

DNA methylation represses FMR-1 transcription in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Molecular cytogenetic study of supernumerary marker chromosomes in an unselected group of children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Effect of regional DNA methylation on gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Altering gene expression with 5-azacytidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Regulation of the expression of the tissue transglutaminase gene by DNA methylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3' CpG clusters: implications for X chromosome dosage compensation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Cytosine methylation in CTF and Sp1 recognition sites of an HSV tk promoter: effects on transcription in vivo and on factor binding in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Methylation of genomes and genes at the invertebrate-vertebrate boundary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Inhibition of herpes simplex thymidine kinase gene expression by DNA methylation is an indirect effect.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Methyl CpG-binding proteins and transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Active repression of methylated genes by the chromosomal protein MBD1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Identification and characterization of a family of mammalian methyl-CpG binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Dynamic analysis of proviral induction and De Novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

A Transient Histone Hyperacetylation Signal Marks Nucleosomes for Remodeling at the PHO8 Promoter In Vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Genome-wide location and function of DNA binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Analysis of chromatin-immunopurified MeCP2-associated fragments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

DNA methylation models histone acetylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

CpG methylation remodels chromatin structure in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Nucleosome assembly on methylated CGG triplet repeats in the fragile X mental retardation gene 1 promoter.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Trinucleotide repeats that expand in human disease form hairpin structures in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

Transcriptional repression by the SMRT-mSin3 corepressor: multiple interactions, multiple mechanisms, and a potential role for TFIIB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900682-4

10.1016/S0006-291X(02)00682-4

7 January 2021

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12099676