(Q34728961)

4 August 2017

title

Separation of oxidized variants of a monoclonal antibody by anion-exchange (English)

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4 August 2017

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Glen Teshima

1

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4 August 2017

Ming-Xiang Li

2

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4 August 2017

Rahima Danishmand

3

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4 August 2017

Chidi Obi

4

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4 August 2017

Robert To

5

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4 August 2017

Carol Huang

6

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4 August 2017

Jacob Kung

7

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4 August 2017

Vafa Lahidji

8

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4 August 2017

Joel Freeberg

9

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4 August 2017

Lauren Thorner

10

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4 August 2017

Milan Tomic

11

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4 August 2017

language of work or name

English

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publication date

16 November 2010

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Journal of Chromatography

4 August 2017

published in

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4 August 2017

volume

1218

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4 August 2017

issue

15

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4 August 2017

page(s)

2091-2097

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Identification and quantification of degradations in the Asp-Asp motifs of a recombinant monoclonal antibody

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Beta-elimination and peptide bond hydrolysis: two distinct mechanisms of human IgG1 hinge fragmentation upon storage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Identification and characterization of deamidation sites in the conserved regions of human immunoglobulin gamma antibodies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: identification and effect on binding affinity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Labile disulfide bonds and free thiol groups in human IgG. I. Assignment to IgG1 and IgG2 subclasses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Stability of protein pharmaceuticals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Isolation and characterization of a succinimide variant of methionyl human growth hormone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Separation of populations of antibody variants by fine tuning of hydrophobic-interaction chromatography operating conditions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Structure and stability changes of human IgG1 Fc as a consequence of methionine oxidation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Cation exchange-HPLC and mass spectrometry reveal C-terminal amidation of an IgG1 heavy chain.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Detecting deamidation products in proteins by electron capture dissociation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Reversed-phase liquid chromatography/mass spectrometry analysis of reduced monoclonal antibodies in pharmaceutics

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

In vivo deamidation characterization of monoclonal antibody by LC/MS/MS.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Development of an analytical reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry method for characterization of recombinant antibodies

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Identification of multiple sources of charge heterogeneity in a recombinant antibody.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065544

Interheavy disulfide bridge in immunoglobulin G (IgG) reacting with dithionitrobenzoate. A unique feature in serum proteins

26 October 2018

1 reference

12 December 2020

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

1 reference

12 December 2020

Validation of an HPLC method for the analysis of the charge heterogeneity of the recombinant monoclonal antibody IDEC-C2B8 after papain digestion

1 reference

12 December 2020

Non-enzymatic hinge region fragmentation of antibodies in solution

1 reference

12 December 2020

Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature

1 reference

12 December 2020

Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody

1 reference

12 December 2020

10.1016/J.CHROMA.2010.10.107

Identifiers

DOI

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4 August 2017

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4 August 2017

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