(Q34736496)

4 August 2017

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title

Epitope spreading in systemic lupus erythematosus: identification of triggering peptide sequences (English)

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systemic lupus erythematosus

4 August 2017

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author name string

Fanny Monneaux

series ordinal

1

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PubMed ID

12115171

4 August 2017

Sylviane Muller

series ordinal

2

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4 August 2017

1 June 2002

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4 August 2017

Arthritis & Rheumatology

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4 August 2017

46

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4 August 2017

6

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4 August 2017

1430-1438

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Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL lpr/lpr antibodies

4 August 2017

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A novel epitope on the C-terminus of SmD1 is recognized by the majority of sera from patients with systemic lupus erythematosus

21 January 2018

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IgG antibodies from patients with primary Sjögren's syndrome and systemic lupus erythematosus recognize different epitopes in 60-kD SSA/Ro protein

21 January 2018

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Analysis of B-cell epitopes of the Ro/SS-A autoantigen

21 January 2018

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Key sequences involved in the spreading of the systemic autoimmune response to spliceosomal proteins

21 January 2018

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Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus

21 January 2018

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Major peptide autoepitopes for nucleosome-specific T cells of human lupus

21 January 2018

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T cell epitope mapping of the Smith antigen reveals that highly conserved Smith antigen motifs are the dominant target of T cell immunity in systemic lupus erythematosus

21 January 2018

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Strong acceleration of murine lupus by injection of the SmD1(83-119) peptide.

21 January 2018

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Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

21 January 2018

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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

21 January 2018

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Self antigens and epitope spreading in systemic autoimmunity

21 January 2018

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Molecular mimicry: a critical look at exemplary instances in human diseases

21 January 2018

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Molecular mimicry and the role of B lymphocytes in the processing of autoantigens

21 January 2018

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Epitope mimics and determinant spreading: pathways to autoimmunity

21 January 2018

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Driver clones and determinant spreading

21 January 2018

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Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes

21 January 2018

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Spreading of the immune response to different myelin basic protein peptides in chronic experimental autoimmune encephalomyelitis in B10.RIII mice

21 January 2018

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21 January 2018

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An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus

21 January 2018

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B and T cell responses to the spliceosomal heterogeneous nuclear ribonucleoproteins A2 and B1 in normal and lupus mice

21 January 2018

1 reference

Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity

21 January 2018

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Immune responses to Ro60 and its peptides in mice. I. The nature of the immunogen and endogenous autoantigen determine the specificities of the induced autoantibodies

21 January 2018

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Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens La (SS-B) and Ro (SS-A).

21 January 2018

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Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice.

21 January 2018

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Epitope patterns of Anti-RNP antibodies in rheumatic diseases evidence for an antigen-driven autoimmune response

21 January 2018

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Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes

21 January 2018

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Fine specificity of autoantibodies to La/SSB: epitope mapping, and characterization.

21 January 2018

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The frequency of high avidity T cells determines the hierarchy of determinant spreading

21 January 2018

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The role of autoantigens in autoimmune disease

21 January 2018

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Antigen-specific therapy for autoimmune disease

21 January 2018

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Control of rheumatoid arthritis by oral tolerance

21 January 2018

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The potential use of peptides and vaccination to treat systemic lupus erythematosus

21 January 2018

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Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens.

21 January 2018

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Post-translational protein modifications in antigen recognition and autoimmunity

21 January 2018

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

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Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules

21 January 2018

1 reference

The mechanism by which a peptide based on complementarity-determining region-1 of a pathogenic anti-DNA auto-Ab ameliorates experimental systemic lupus erythematosus

21 January 2018

1 reference

Treatment with a consensus peptide based on amino acid sequences in autoantibodies prevents T cell activation by autoantigens and delays disease onset in murine lupus

21 January 2018

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Epitope mapping of the Ro/SSA60KD autoantigen reveals disease-specific antibody-binding profiles

21 January 2018

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Sera from patients with rheumatic diseases recognize different epitope regions on the 52-kD Ro/SS-A protein

21 January 2018

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B-cell epitope spreading in autoimmunity

21 January 2018

1 reference

B and T cell immune response to small nuclear ribonucleoprotein particles in lupus mice: autoreactive CD4(+) T cells recognize a T cell epitope located within the RNP80 motif of the 70K protein

21 January 2018

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Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination

21 January 2018

1 reference

Maturation of the humoral autoimmune response to epitopes of GAD in preclinical childhood type 1 diabetes

21 January 2018

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The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis

21 January 2018

1 reference

Shifting T-cell activation thresholds in autoimmunity and determinant spreading

21 January 2018

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Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes

21 January 2018

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The appearance of U1 RNP antibody specificities in sequential autoimmune human antisera follows a characteristic order that implicates the U1-70 kd and B'/B proteins as predominant U1 RNP immunogens

21 January 2018

1 reference

Murine models of systemic lupus erythematosus: B and T cell responses to spliceosomal ribonucleoproteins in MRL/Fas(lpr) and (NZB x NZW)F(1) lupus mice

21 January 2018

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Immunization of mice with human 60-kd Ro peptides results in epitope spreading if the peptides are highly homologous between human and mouse

21 January 2018

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Study of antibody and T cell responses in rabbits immunized with synthetic human B cell epitope analogues of La (SSB) autoantigen

21 January 2018

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No evidence of epitope spreading after immunization with the major Sm epitope P-P-G-M-R-P-P anchored to sequential oligopeptide carriers (SOCs)

21 January 2018

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Influence of antigen organization on the development of lupus autoantibodies

21 January 2018

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Do B cells drive the diversification of immune responses?

21 January 2018

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Mapping of epitopes on U1 snRNP polypeptide A with synthetic peptides and autoimmune sera

21 January 2018

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T cell epitope mapping of U1-A RNP

21 January 2018

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Immunodominant RNA recognition motifs of human nucleolin/C23

21 January 2018

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Human autoantibodies directed against the RNA recognition motif of La (SS-B) bind to a conformational epitope present on the intact La (SS-B)/Ro (SS-A) ribonucleoprotein particle

21 January 2018

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Oral tolerance: mechanisms and therapeutic applications.

21 January 2018

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Importance of dose of type II collagen in suppression of collagen-induced arthritis by nasal tolerance

21 January 2018

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SR proteins are autoantigens in patients with systemic lupus erythematosus. Importance of phosphoepitopes

21 January 2018

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Inhibition of experimental autoimmune encephalomyelitis in SJL mice by oral administration of retro-inverso derivative of encephalitogenic epitope P87-99

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/ART.10263

1 reference

4 August 2017

1 reference

PubMed ID

12115171