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A herpesvirus virulence factor inhibits dendritic cell maturation through protein phosphatase 1 and Ikappa B kinase.
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Europe PubMed Central
PMCID
3067875
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20 January 2020
title
A herpesvirus virulence factor inhibits dendritic cell maturation through protein phosphatase 1 and Ikappa B kinase
(English)
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PMCID
3067875
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20 January 2020
main subject
dendritic cell
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author
Zhipeng Yan
series ordinal
2
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Europe PubMed Central
PMCID
3067875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
author name string
Huali Jin
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1
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3067875
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20 January 2020
Yijie Ma
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3
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3067875
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20 January 2020
Youjia Cao
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4
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3067875
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20 January 2020
Bin He
series ordinal
5
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3067875
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
language of work or name
English
0 references
publication date
19 January 2011
1 reference
stated in
Europe PubMed Central
PMCID
3067875
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retrieved
20 January 2020
published in
Journal of Virology
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Europe PubMed Central
PMCID
3067875
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
volume
85
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Europe PubMed Central
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20 January 2020
issue
7
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PMCID
3067875
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
page(s)
3397-3407
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PMCID
3067875
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20 January 2020
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The gamma 1 34.5 protein of herpes simplex virus 1 is required to interfere with dendritic cell maturation during productive infection
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HSV-1 ICP27 suppresses NF-kappaB activity by stabilizing IkappaBalpha
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A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cells
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HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein
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Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome
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The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR.
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Herpes simplex virus disrupts NF-kappaB regulation by blocking its recruitment on the IkappaBalpha promoter and directing the factor on viral genes
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7 July 2018
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Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2
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7 July 2018
Immature monocyte-derived dendritic cells are productively infected with herpes simplex virus type 1.
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7 July 2018
Herpes simplex virus infections
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PubMed Central
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7 July 2018
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
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7 July 2018
The gamma134.5 protein of herpes simplex virus 1 has the structural and functional attributes of a protein phosphatase 1 regulatory subunit and is present in a high molecular weight complex with the enzyme in infected cells
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
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7 July 2018
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-
1 reference
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PubMed Central
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7 July 2018
Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models
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PubMed Central
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7 July 2018
Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
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7 July 2018
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
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7 July 2018
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
1 reference
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PubMed Central
reference URL
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7 July 2018
The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
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7 July 2018
Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
26 October 2018
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
26 October 2018
Cutting Edge: Conventional CD8α+ Dendritic Cells Are Preferentially Involved in CTL Priming After Footpad Infection with Herpes Simplex Virus-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
26 October 2018
Herpes simplex virus infection of dendritic cells: balance among activation, inhibition, and immunity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
26 October 2018
Inhibition of dendritic cell maturation by herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
26 October 2018
Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
26 October 2018
Type I Interferon Induction Pathway, but Not Released Interferon, Participates in the Maturation of Dendritic Cells Induced by Negative‐Strand RNA Viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3067875
retrieved
9 December 2018
Identifiers
DOI
10.1128/JVI.02373-10
1 reference
stated in
Europe PubMed Central
PMCID
3067875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PMCID
3067875
1 reference
stated in
Europe PubMed Central
PMCID
3067875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PubMed ID
21248029
1 reference
stated in
Europe PubMed Central
PMCID
3067875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248029%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
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