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Self-assembled FUS binds active chromatin and regulates gene transcription.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
title
Self-assembled FUS binds active chromatin and regulates gene transcription
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
main subject
FUS RNA binding protein
1 reference
stated in
GOA release 2020-03-11
protein homooligomerization
1 reference
stated in
GOA release 2020-03-11
self-assembly
1 reference
based on heuristic
inferred from title
author
Jozsef Gal
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
author name string
Liuqing Yang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
Jing Chen
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
Haining Zhu
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
language of work or name
English
0 references
publication date
1 December 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
volume
111
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
issue
50
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
page(s)
17809-17814
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
cites work
FUS is sequestered in nuclear aggregates in ALS patient fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Compromised paraspeckle formation as a pathogenic factor in FUSopathies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
RNA seeds higher-order assembly of FUS protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains
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PubMed Central
reference URL
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7 July 2018
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Stress granules as crucibles of ALS pathogenesis.
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PubMed Central
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7 July 2018
Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Blessings in disguise: biological benefits of prion-like mechanisms
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PubMed Central
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7 July 2018
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
The self-interaction of native TDP-43 C terminus inhibits its degradation and contributes to early proteinopathies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
A yeast functional screen predicts new candidate ALS disease genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Genome-wide profiling of salt fractions maps physical properties of chromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
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7 July 2018
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Stress granules: the Tao of RNA triage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Structural rearrangements near the chromophore influence the maturation speed and brightness of DsRed variants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Stress granule assembly is mediated by prion-like aggregation of TIA-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Refined crystal structure of DsRed, a red fluorescent protein from coral, at 2.0-A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
The in vivo minigene approach to analyze tissue-specific splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273402
retrieved
7 July 2018
Identifiers
DOI
10.1073/PNAS.1414004111
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
ADS bibcode
2014PNAS..11117809Y
0 references
Fatcat ID
release_fbf42nayindhbbm5xovmnedrs4
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/fbf42nayindhbbm5xovmnedrs4
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
4273402
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
PubMed publication ID
25453086
1 reference
stated in
Europe PubMed Central
PMC publication ID
4273402
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453086%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
ResearchGate publication ID
269178597
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