(Q34758698)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

1 reference

title

Glucocorticoid receptor variants: clinical implications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

R H DeRijk

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

M Schaaf

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 June 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Steroid Biochemistry and Molecular Biology

11 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

81

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

103-122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

Role of hydrophobic amino acid clusters in the transactivation activity of the human glucocorticoid receptor

11 November 2019

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Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids

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The human glucocorticoid receptor promoter upstream sequences contain binding sites for the ubiquitous transcription factor, Yin Yang 1.

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High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.

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The neuroendocrinology of depression and chronic stress

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AU-rich elements: characterization and importance in mRNA degradation

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Increased number of glucocorticoid receptor-beta-expressing cells in the airways in fatal asthma

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Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

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Inhibition of gene expression by steroid hormone receptors via a negative glucocorticoid response element: evidence for the involvement of DNA-binding and agonistic effects of the antiglucocorticoid/antiprogestin RU486.

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7 January 2021

Why Dexamethasone Poorly Penetrates in Brain.

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7 January 2021

Stress and cognition: are corticosteroids good or bad guys?

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7 January 2021

Cytokines and the brain corticosteroid receptor balance: relevance to pathophysiology of neuroendocrine-immune communication.

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7 January 2021

Brain corticosteroid receptor balance in health and disease

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7 January 2021

Natural variants of the beta isoform of the human glucocorticoid receptor do not alter sensitivity to glucocorticoids

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7 January 2021

A TthIII1 polymorphism on the 5′ flanking region of the glucocorticoid receptor gene (GRL)

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7 January 2021

Five missense variants in the amino-terminal domain of the glucocorticoid receptor: no association with puerperal psychosis or schizophrenia

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7 January 2021

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

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7 January 2021

Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma

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7 January 2021

Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer

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7 January 2021

Functional domains of the human glucocorticoid receptor

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7 January 2021

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

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7 January 2021

Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma.

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7 January 2021

GRbeta expression in nasal polyp inflammatory cells and its relationship to the anti-inflammatory effects of intranasal fluticasone

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7 January 2021

Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens

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7 January 2021

Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor

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7 January 2021

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

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Primary structure and expression of a functional human glucocorticoid receptor cDNA

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The corticosteroid receptor hypothesis of depression

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7 January 2021

Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis

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Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene.

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7 January 2021

Human adrenocorticotropin-secreting pituitary adenomas show frequent loss of heterozygosity at the glucocorticoid receptor gene locus.

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7 January 2021

A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo

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7 January 2021

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance

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7 January 2021

Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

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7 January 2021

Deletion of a consensus oestrogen response element half-site in the glucocorticoid receptor of human multiple myeloma

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7 January 2021

Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.

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7 January 2021

Nelson's syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene.

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7 January 2021

Corticosteroid actions in hippocampus require DNA binding of glucocorticoidreceptor homodimers

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7 January 2021

A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development

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7 January 2021

Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance

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7 January 2021

Clinical aspects of glucocorticoid sensitivity

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7 January 2021

Cortisol receptor resistance: the variability of its clinical presentation and response to treatment

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7 January 2021

Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma.

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7 January 2021

Is there a role for glucocorticoid receptor beta in glucocorticoid-dependent asthmatics?

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7 January 2021

Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta

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7 January 2021

High penetrance, overweight, and glucocorticoid receptor variant: case-control study

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7 January 2021

Association and linkage analyses of glucocorticoid receptor gene markers in essential hypertension

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7 January 2021

Identification of single amino acid substitutions of Cys-736 that affect the steroid-binding affinity and specificity of the glucocorticoid receptor using phenotypic screening in yeast

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7 January 2021

Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and binding

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7 January 2021

Valine 571 functions as a regional organizer in programming the glucocorticoid receptor for differential binding of glucocorticoids and mineralocorticoids

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7 January 2021

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

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7 January 2021

A mutation of the glucocorticoid receptor in primary cortisol resistance

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7 January 2021

A transgenic model of visceral obesity and the metabolic syndrome

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7 January 2021

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7 January 2021

Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways

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7 January 2021

Glucocorticoid receptor alpha and beta isoforms are not mutated in bipolar affective disorder

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7 January 2021

Low level of glucocorticoid receptor messenger ribonucleic acid in pituitary adenomas manifesting Cushing's disease with resistance to a high dose-dexamethasone suppression test.

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7 January 2021

Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1

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7 January 2021

Molecular mechanisms of glucocorticoid inhibition of human proopiomelanocortin gene transcription

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7 January 2021

Characterization of the human glucocorticoid receptor promoter

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7 January 2021

The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action

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7 January 2021

The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function

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7 January 2021

Immunocytochemical analysis of the glucocorticoid receptor alpha isoform (GRalpha) using GRalpha-specific antibody.

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7 January 2021

Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption.

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7 January 2021

Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory

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7 January 2021

Absence of glucocorticoid receptor-beta in mice

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7 January 2021

Glucocorticoid receptor polymorphism, skin vasoconstriction, and other metabolic intermediate phenotypes in normal human subjects

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7 January 2021

An ACTH-producing small cell lung cancer expresses aberrant glucocorticoid receptor transcripts from a normal gene

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7 January 2021

Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene

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7 January 2021

Association between post-dexamethasone cortisol level and blood pressure in depressed inpatients

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7 January 2021

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

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7 January 2021

Steroid receptor interactions with heat shock protein and immunophilin chaperones

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7 January 2021

Expression of the human glucocorticoid receptor alpha and beta isoforms in human respiratory epithelial cells and their regulation by dexamethasone.

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7 January 2021

Structure/Function of the Human Glucocorticoid Receptor: Tyrosine 735 Is Important for Transactivation

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7 January 2021

DNA binding of the glucocorticoid receptor is not essential for survival

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7 January 2021

Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing.

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7 January 2021

Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphoryl

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7 January 2021

Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase

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7 January 2021

Tsp509I polymorphism in exon 2 of the glucocorticoid receptor gene in relation to obesity and cortisol secretion: cohort study

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7 January 2021

A polymorphism of the 5'-flanking region of the glucocorticoid receptor gene locus is associated with basal cortisol secretion in men

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7 January 2021

A glucocorticoid receptor gene marker is associated with abdominal obesity, leptin, and dysregulation of the hypothalamic-pituitary-adrenal axis

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7 January 2021

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7 January 2021

Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance

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7 January 2021

Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces

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7 January 2021

Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action

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7 January 2021

Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy

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7 January 2021

The DNA and steroid binding domains of the glucocorticoid receptor are not altered in mononuclear cells of treated CLL patients

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7 January 2021

Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor beta-isoform

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7 January 2021

Reduced glucocorticoid binding affinity in asthma is related to ongoing allergic inflammation

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7 January 2021

High constitutive glucocorticoid receptor beta in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids

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7 January 2021

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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7 January 2021

Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation

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7 January 2021

Function of a truncated glucocorticoid receptor form at a negative glucocorticoid response element in the proopiomelanocortin gene

1 reference

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7 January 2021

Glucocorticoid receptor Bcl I variant is associated with an increased atherogenic profile in response to long-term overfeeding

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7 January 2021

Amplitude, but not frequency, modulation of adrenocorticotropin secretory bursts gives rise to the nyctohemeral rhythm of the corticotropic axis in man.

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7 January 2021

Spontaneous Hypercortisolism without Cushing's Syndrome

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7 January 2021

Abnormalities of glucocorticoid metabolism and the renin-angiotensin system: a four-corners approach to the identification of genetic determinants of blood pressure

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7 January 2021

An association between a Bc1I restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women

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7 January 2021

Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein

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7 January 2021

Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance.

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7 January 2021

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product.

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7 January 2021

Regulation of glucocorticoid receptor alpha and beta isoforms and type I 11beta-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance?

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7 January 2021

Differential mRNA expression of the two mineralocorticoid receptor splice variants within the human brain: structure analysis of their different DNA binding domains

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7 January 2021

Glucocorticoids and immune function: unknown dimensions and new frontiers

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https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900062-6

7 January 2021

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2802%2900062-6

7 January 2021

10.1016/S0960-0760(02)00062-6

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DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12137800%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference