(Q34767012)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Increased IGF-1 in muscle modulates the phenotype of severe SMA mice (English)

1 reference

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22 January 2020

1 reference

8

1 reference

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22 January 2020

author name string

Marta Bosch-Marcé

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Claribel D Wee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Tara L Martinez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Celeste E Lipkes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Dong W Choe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Lingling Kong

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

James P Van Meerbeke

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Charlotte J Sumner

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

publication date

16 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

published in

Human Molecular Genetics

1 reference

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22 January 2020

volume

20

1 reference

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22 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

1844-1853

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy

7 July 2018

1 reference

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Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Cardiac defects contribute to the pathology of spinal muscular atrophy models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Digital necroses and vascular thrombosis in severe spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: roles in skeletal muscle growth and differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Vascular perfusion abnormalities in infants with spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Inhibition of myostatin does not ameliorate disease features of severe spinal muscular atrophy mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Impaired synaptic vesicle release and immaturity of neuromuscular junctions in spinal muscular atrophy mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Modeling spinal muscular atrophy in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Congenital heart disease is a feature of severe infantile spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

The changing natural history of spinal muscular atrophy type 1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Chaperoning ribonucleoprotein biogenesis in health and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

The SMN complex: an assembly machine for RNPs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

The ABCs of IGF-I isoforms: impact on muscle hypertrophy and implications for repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

The neuroprotective effects of a locally acting IGF-1 isoform.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

The role of histone acetylation in SMN gene expression.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Intact satellite cells lead to remarkable protection against Smn gene defect in differentiated skeletal muscle.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Muscle could be the therapeutic target in SMA treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

The neurobiology of childhood spinal muscular atrophy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Identification and characterization of a spinal muscular atrophy-determining gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Acute infantile spinal muscular atrophy. Muscle apoptosis as a proposed pathogenetic mechanism.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071675

Childhood spinal muscular atrophy induces alterations in contractile and regulatory protein isoform expressions.

7 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Exercise-induced activation of NMDA receptor promotes motor unit development and survival in a type 2 spinal muscular atrophy model mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Constitutive muscular abnormalities in culture in spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Hypoglycaemia in spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

In vivo NMDA receptor activation accelerates motor unit maturation, protects spinal motor neurons, and enhances SMN2 gene expression in severe spinal muscular atrophy mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

Change in synaptic channel gating during neuromuscular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR067

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

21 January 2018

1 reference

12 December 2020

Hypomorphic Smn knockdown C2C12 myoblasts reveal intrinsic defects in myoblast fusion and myotube morphology

1 reference

12 December 2020

Congenital heart defects in spinal muscular atrophy type I: a clinical report of two siblings and a review of the literature

1 reference

12 December 2020

Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy

1 reference

12 December 2020

Target-derived trophic effect on skeletal muscle innervation in senescent mice

1 reference

12 December 2020

A post-natal decrease in acetylcholine channel open time at rat end-plates

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR067

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325354%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21325354

1 reference