(Q34770383)

4 August 2017

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title

Maintaining the norm: T-cell homeostasis (English)

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4 August 2017

Stephen C Jameson

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4 August 2017

1 August 2002

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Nature Reviews Immunology

4 August 2017

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4 August 2017

2

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4 August 2017

547-556

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4 August 2017

8

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Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

4 August 2017

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Estimating the precursor frequency of naive antigen-specific CD8 T cells

31 March 2020

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Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses

31 March 2020

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The life-span and recirculation of marrow-derived small lymphocytes from the rat thoracic duct

31 March 2020

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Circulating T and B lymphocytes of the mouse. II. Lifespan.

31 March 2020

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Turnover of naive- and memory-phenotype T cells

31 March 2020

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Lifespan of human lymphocyte subsets defined by CD45 isoforms

31 March 2020

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Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

31 March 2020

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Factors influencing T-cell turnover in HIV-1-seropositive patients

31 March 2020

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Interconversion of CD45R subsets of CD4 T cells in vivo

31 March 2020

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MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

31 March 2020

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Differential requirements for survival and proliferation of CD8 naïve or memory T cells

31 March 2020

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Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses

31 March 2020

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Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells

31 March 2020

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Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

31 March 2020

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Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition

31 March 2020

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CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection

31 March 2020

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Naïve cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?

31 March 2020

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The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

31 March 2020

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Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts

31 March 2020

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Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

31 March 2020

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Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes

31 March 2020

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Cutting edge: naive T cells masquerading as memory cells

31 March 2020

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Differential Survival of Naive CD4 and CD8 T Cells

31 March 2020

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Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells

31 March 2020

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Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation

31 March 2020

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Peripheral selection of the T cell repertoire

31 March 2020

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Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

31 March 2020

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Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype

31 March 2020

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Cell division in the compartment of naive and memory T lymphocytes.

31 March 2020

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Selection of the T cell repertoire.

31 March 2020

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Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

31 March 2020

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Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

31 March 2020

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Persistence of memory CD8 T cells in MHC class I-deficient mice

31 March 2020

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Mature CD4+ T Cells Perceive a Positively Selecting Class II MHC/Peptide Complex in the Periphery

31 March 2020

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CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling

31 March 2020

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Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain

31 March 2020

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ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells

31 March 2020

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Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

31 March 2020

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How alpha beta T cells deal with induced TCR alpha ablation

31 March 2020

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How much TCR does a T cell need?

31 March 2020

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Long-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lck

31 March 2020

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Sensory adaptation in naive peripheral CD4 T cells

31 March 2020

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Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene

31 March 2020

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Impaired survival of T helper cells in the absence of CD4.

31 March 2020

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Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors

31 March 2020

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Cellular competition modulates survival and selection of CD8+ T cells

31 March 2020

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Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire.

31 March 2020

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The Shaping of the T Cell Repertoire

31 March 2020

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Cytokines and autoimmunity

31 March 2020

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Homeostasis of alpha beta TCR+ T cells.

31 March 2020

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Cytokines and immunodeficiency diseases

31 March 2020

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Cytokines: IL-21 joins the gamma(c)-dependent network?

31 March 2020

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Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division

31 March 2020

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Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

31 March 2020

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

31 March 2020

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

31 March 2020

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IL-7 enhances the survival and maintains the size of naive T cells

31 March 2020

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T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo

31 March 2020

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Interleukin-7: master regulator of peripheral T-cell homeostasis?

31 March 2020

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Cytokine-induced survival of activated T cells in vitro and in vivo

31 March 2020

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Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

31 March 2020

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IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development

31 March 2020

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Peripheral expression of Jak3 is required to maintain T lymphocyte function

31 March 2020

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The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression

31 March 2020

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Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

31 March 2020

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Interleukin-7: physiological roles and mechanisms of action

31 March 2020

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LKLF: A transcriptional regulator of single-positive T cell quiescence and survival

31 March 2020

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Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

31 March 2020

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Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor

31 March 2020

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Il-12 enhances CD8 T cell homeostatic expansion

31 March 2020

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Autologous regulation of naive T cell homeostasis within the T cell compartment.

31 March 2020

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IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation

31 March 2020

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Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

31 March 2020

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A potential role for interleukin-7 in T-cell homeostasis

31 March 2020

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Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

31 March 2020

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Massive expansion of antigen-specific CD8+ T cells during an acute virus infection

31 March 2020

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T cells compete for access to antigen-bearing antigen-presenting cells

31 March 2020

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T cells down-modulate peptide-MHC complexes on APCs in vivo.

31 March 2020

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Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool

31 March 2020

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A ligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunity

31 March 2020

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Homeostatic expansion occurs independently of costimulatory signals

31 March 2020

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A closer look at homeostatic proliferation of CD4+ T cells: costimulatory requirements and role in memory formation.

31 March 2020

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Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments

31 March 2020

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Conversion of naive T cells to a memory-like phenotype in lymphopenic hosts is not related to a homeostatic mechanism that fills the peripheral naive T cell pool.

31 March 2020

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Linear differentiation of cytotoxic effectors into memory T lymphocytes

31 March 2020

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Population biology of lymphocytes: the flight for survival

31 March 2020

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The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools

31 March 2020

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Peripheral selection of T cell repertoires: the role of continuous thymus output

31 March 2020

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Cytotoxic T-cell memory without antigen

31 March 2020

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Class II-independent generation of CD4 memory T cells from effectors.

31 March 2020

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Impairment of immunological memory in the absence of MHC despite survival of memory T cells

31 March 2020

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Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

31 March 2020

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Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules

31 March 2020

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A role for antigen in the maintenance of immunological memory

31 March 2020

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Priming of memory but not effector CD8 T cells by a killed bacterial vaccine

31 March 2020

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31 March 2020

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Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15

31 March 2020

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Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

31 March 2020

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IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

31 March 2020

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Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

31 March 2020

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Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

31 March 2020

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Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

31 March 2020

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An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma

31 March 2020

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Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells

31 March 2020

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Control of homeostasis of CD8+ memory T cells by opposing cytokines.

31 March 2020

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Gamma chain required for naïve CD4+ T cell survival but not for antigen proliferation.

31 March 2020

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Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

31 March 2020

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Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes

31 March 2020

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Differential contribution of thymic outputs and peripheral expansion in the development of peripheral T cell pools

31 March 2020

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Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

31 March 2020

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Identification of a human recent thymic emigrant phenotype

31 March 2020

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31 March 2020

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31 March 2020

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Immunological memory and protective immunity: understanding their relation

31 March 2020

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Aging and lymphokine production by T cell subsets

31 March 2020

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T-cell homeostasis in HIV-1 infection

31 March 2020

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Extensive lymphopenia due to apoptosis of uninfected lymphocytes in acute measles patients

31 March 2020

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Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans

31 March 2020

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Division rate and phenotypic differences discriminate alloreactive and nonalloreactive T cells transferred in lethally irradiated mice

31 March 2020

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Interleukin-7 restores immunity in athymic T-cell-depleted hosts

31 March 2020

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Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis

31 March 2020

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Post-thymectomy autoimmunity: abnormal T-cell homeostasis

31 March 2020

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T cell regulation: a special job or everyone's responsibility?

31 March 2020

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T cell homeostasis and systemic autoimmunity

31 March 2020

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Regulatory T cells in the control of immune pathology.

31 March 2020

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Suppressor T cells--they're back and critical for regulation of autoimmunity!

31 March 2020

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Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease

31 March 2020

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CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

31 March 2020

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MHC-dependent survival of naïve T cells? A complicated answer to a simple question

31 March 2020

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Regulation of naïve and memory T-cell homeostasis

31 March 2020

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Homeostatic expansion versus antigen-driven proliferation: common ends by different means?

31 March 2020

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Naive CD4(+) lymphocytes convert to anergic or memory-like cells in T cell-deprived recipients.

31 March 2020

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Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

31 March 2020

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CTLA-4: new insights into its biological function and use in tumor immunotherapy

31 March 2020

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31 March 2020

Identifiers

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PubMed ID

12154374