(Q34770666)

4 August 2017

title

Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms (English)

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G protein-coupled receptor

4 August 2017

main subject

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author name string

Sonemany Salinthone

1

1 reference

4 August 2017

Robynn V Schillace

2

1 reference

4 August 2017

Catherine Tsang

3

1 reference

4 August 2017

John W Regan

4

1 reference

4 August 2017

Dennis N Bourdette

5

1 reference

4 August 2017

Daniel W Carr

6

1 reference

4 August 2017

publication date

30 October 2010

1 reference

Journal of Nutritional Biochemistry

4 August 2017

published in

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4 August 2017

volume

22

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4 August 2017

issue

7

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4 August 2017

page(s)

681-690

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Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential

4 August 2017

cites work

1 reference

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Adenylyl cyclases as innovative therapeutic goals.

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

7 July 2018

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Lipoic acid stimulates cAMP production via the EP2 and EP4 prostanoid receptors and inhibits IFN gamma synthesis and cellular cytotoxicity in NK cells

7 July 2018

1 reference

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Lipoic acid: a novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS.

7 July 2018

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The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects.

7 July 2018

1 reference

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"Soluble" adenylyl cyclase-generated cyclic adenosine monophosphate promotes fast migration in PC12 cells

7 July 2018

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Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP

7 July 2018

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7 July 2018

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Adenosine-mediated inhibition of cytotoxic activity and cytokine production by IL-2/NKp46-activated NK cells: involvement of protein kinase A isozyme I (PKA I).

7 July 2018

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Effects of adenosine on adhesion molecule expression and cytokine production in human PBMC depend on the receptor subtype activated

7 July 2018

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Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity

7 July 2018

1 reference

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Death or survival--progesterone-dependent cell fate decisions in the human endometrial stroma

7 July 2018

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The role of protein kinase A and A-kinase anchoring proteins in modulating T-cell activation: progress and future directions

7 July 2018

1 reference

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Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Differential activity of lipoic acid enantiomers in cell culture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Cyclic nucleotide signalling: a molecular approach to drug discovery for Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Alpha lipoic acid inhibits human T-cell migration: implications for multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Alpha-lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Calcium regulation of the soluble adenylyl cyclase expressed in mammalian spermatozoa

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Structural basis for activation of G-protein-coupled receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

7 July 2018

1 reference

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G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Do mammalian cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Prostanoid receptors: subtypes and signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Role of cAMP-dependent signal transduction in the control of T lymphocyte activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Specific expression of soluble adenylyl cyclase in male germ cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Production of IL-10 by melanoma cells: examination of its role in immunosuppression mediated by melanoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Target-effector cell interaction in the natural killer cell system. V. Energy requirements, membrane integrity, and the possible involvement of lysosomal enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

The metabolism of dl-[1, 6-14C]lipoic acid in the rat

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Lipoic acid stimulates cAMP production in T lymphocytes and NK cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Prostaglandin E2 suppressed IL-15-mediated human NK cell function through down-regulation of common gamma-chain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Expression of mRNA for interferon-gamma, interleukin-10, and interleukin-12 (p40) in normal gastric mucosa and in mucosa infected with Helicobacter pylori

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Neuroprotective effects of alpha-lipoic acid and its enantiomers demonstrated in rodent models of focal cerebral ischemia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Alpha-lipoic acid supplementation prevents symptoms of vitamin E deficiency

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

Alpha-lipoic acid prevents buthionine sulfoximine-induced cataract formation in newborn rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072460

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

26 October 2018

1 reference

12 December 2020

The effect of temperature and ionic strength on the apparent Ca-affinity of EGTA and the analogous Ca-chelators BAPTA and dibromo-BAPTA

1 reference

12 December 2020

Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells

1 reference

12 December 2020

A low resolution model for the interaction of G proteins with G protein-coupled receptors

1 reference

12 December 2020

(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo

1 reference

12 December 2020

Thioctic acid induces dose-dependent sprouting of neurites in cultured rat neuroblastoma cells

1 reference

12 December 2020

The role of cAMP regulation in controlling inflammation

1 reference

12 December 2020

Interaction of alpha-lipoic acid enantiomers and homologues with the enzyme components of the mammalian pyruvate dehydrogenase complex

1 reference

12 December 2020

Dose/response curves of lipoic acid R-and S-forms in the working rat heart during reoxygenation: superiority of the R-enantiomer in enhancement of aortic flow

1 reference

12 December 2020

Protection against peroxynitrite-dependent tyrosine nitration and α 1 -antiproteinase inactivation by oxidized and reduced lipoic acid

1 reference

12 December 2020

Alpha-lipoic acid: antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy

1 reference

12 December 2020

A conserved threonine in the second extracellular loop of the human EP2 and EP4 receptors is required for ligand binding

1 reference

12 December 2020

Alpha-lipoic acid reduces expression of vascular cell adhesion molecule-1 and endothelial adhesion of human monocytes after stimulation with advanced glycation end products

1 reference

12 December 2020

Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers

1 reference

12 December 2020

Gastric emptying in patients with insulin dependent diabetes mellitus and bioavailability of thioctic acid-enantiomers

1 reference

12 December 2020

10.1016/J.JNUTBIO.2010.05.008

Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference