(Q34777845)

4 August 2017

title

Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair (English)

1 reference

4 August 2017

Dongping Wei

1

1 reference

4 August 2017

Leslie A Parsels

2

1 reference

4 August 2017

David Karnak

3

1 reference

4 August 2017

Mary A Davis

4

1 reference

4 August 2017

Joshua D Parsels

5

1 reference

4 August 2017

Amanda C Marsh

6

1 reference

4 August 2017

Lili Zhao

7

1 reference

4 August 2017

Jonathan Maybaum

8

1 reference

4 August 2017

Theodore S Lawrence

9

1 reference

4 August 2017

Yi Sun

10

1 reference

4 August 2017

Meredith A Morgan

11

1 reference

4 August 2017

language of work or name

English

0 references

publication date

18 June 2013

1 reference

4 August 2017

published in

Clinical Cancer Research

1 reference

4 August 2017

volume

19

1 reference

4 August 2017

issue

16

1 reference

4 August 2017

page(s)

4422-4432

1 reference

Exploiting protein phosphatase inhibitors based on cantharidin analogues for cancer drug discovery.

4 August 2017

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7 July 2018

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7 July 2018

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Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-terminal kinase pathway

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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A synthetic cantharidin analog for the enhancement of doxorubicin suppression of stem cell-derived aggressive sarcoma

7 July 2018

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7 July 2018

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Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.

7 July 2018

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Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response

7 July 2018

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7 July 2018

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The effect of a PP2A inhibitor on the nuclear receptor corepressor pathway in glioma

7 July 2018

1 reference

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A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair

7 July 2018

1 reference

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Mitotic phosphatases: from entry guards to exit guides

7 July 2018

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Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms

7 July 2018

1 reference

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DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

7 July 2018

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7 July 2018

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7 July 2018

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Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.

7 July 2018

1 reference

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Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

The relationship of premature mitosis to cytotoxicity in response to checkpoint abrogation and antimetabolite treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

Radiosensitization of tumour cells by cantharidin and some analogues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

7 July 2018

1 reference

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Fostriecin: chemistry and biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex

7 July 2018

1 reference

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Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

7 July 2018

1 reference

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Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754450

Bayesian hierarchical changepoint methods in modeling the tumor growth profiles in xenograft experiments.

26 October 2018

1 reference

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Mean inactivation dose: a useful concept for intercomparison of human cell survival curves

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23780887

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-13-0788

1 reference

4 August 2017

1 reference

4 August 2017

1 reference