(Q34782375)

English

Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies

scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies (English)

1 reference

Europe PubMed Central

4 August 2017

author name string

Giulia Ghibellini

1

1 reference

Europe PubMed Central

4 August 2017

Elaine M Leslie

2

1 reference

Europe PubMed Central

4 August 2017

Gary M Pollack

3

1 reference

Europe PubMed Central

4 August 2017

Kim L R Brouwer

4

1 reference

Europe PubMed Central

4 August 2017

publication date

30 May 2008

1 reference

Europe PubMed Central

4 August 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

4 August 2017

25

1 reference

Europe PubMed Central

4 August 2017

1851-1860

1 reference

Europe PubMed Central

4 August 2017

8

1 reference

Europe PubMed Central

4 August 2017

Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

The impact of plasma protein binding on the renal transport of organic anions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

A novel method for the determination of biliary clearance in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

The complexities of hepatic drug transport: current knowledge and emerging concepts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Noninvasive assessment of hepatobiliary and renal elimination of cysteinyl leukotrienes by positron emission tomography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Studies of the hepatocellular uptake of the hepatobiliary scintiscanning agent 99mTc-DISIDA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

Technetium-99m-iminodiacetic acid organic anions: review of biokinetics and clinical application in hepatology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

7 July 2018

A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2).

1 reference

https://api.crossref.org/works/10.1007%2FS11095-008-9597-0

21 January 2018

Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

Hepatobiliary kinetics of technetium-99m-IDA analogs: quantification by linear systems theory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

A new diagnostic approach to the Dubin-Johnson syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634848

26 October 2018

Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of pediatric liver transplant recipients using quantitative hepatobiliary scintigraphy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of hepatic functions and biliary dynamics in patients with liver cirrhosis by quantitative scintigraphy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

99mTc-HIDA cholescintigraphy in children with Dubin-Johnson syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional transport of iminodiacetic organic anion analogues between plasma and hepatocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-008-9597-0

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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