(Q34792814)

4 August 2017

1 reference

title

Tumor necrosis factor-alpha in cardiovascular biology and the potential role for anti-tumor necrosis factor-alpha therapy in heart disease (English)

1 reference

4 August 2017

Michael Sack

1

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4 August 2017

publication date

1 April 2002

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Pharmacology & Therapeutics

4 August 2017

published in

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4 August 2017

volume

94

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4 August 2017

issue

1-2

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4 August 2017

page(s)

123-135

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Apoptosis and myocardial infarction

4 August 2017

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Signal transduction in ischemic preconditioning: the role of kinases and mitochondrial K(ATP) channels

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Detection and localization of tumor necrosis factor in human atheroma

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A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis

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Cytokines as emerging targets in the treatment of heart failure

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Tumor necrosis factor-alpha mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression

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Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats

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Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure

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Expression of tumour necrosis factor alpha and accumulation of fibronectin in coronary artery restenotic lesions retrieved by atherectomy

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Safety and efficacy of a soluble P75 tumor necrosis factor receptor (Enbrel, etanercept) in patients with advanced heart failure.

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Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST).

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Tumor necrosis factor-alpha pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury

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Unresolved issues regarding the role of apoptosis in the pathogenesis of ischemic injury and heart failure

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The role of apoptosis in myocardial ischemia: a critical appraisal

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Pathology of Acute and Chronic Coronary Stenting in Humans

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Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure

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7 January 2021

Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia

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7 January 2021

Apoptosis in cardiac diseases--new opportunities for novel therapeutics for heart diseases

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7 January 2021

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion

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7 January 2021

Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta

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7 January 2021

The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia

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7 January 2021

Endotoxin-Induced Myocardial Tumor Necrosis Factor-α Synthesis Depresses Contractility of Isolated Rat Hearts

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7 January 2021

Tumor necrosis factor-alpha upregulates angiotensin II type 1 receptors on cardiac fibroblasts

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7 January 2021

Tumor necrosis factor-alpha is released from the isolated heart undergoing ischemia and reperfusion.

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7 January 2021

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level

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7 January 2021

Differential regulation of myocardial NF kappa B following acute or chronic TNF-alpha exposure

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7 January 2021

Apoptosis: basic mechanisms and implications for cardiovascular disease

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7 January 2021

Expression of inducible nitric oxide synthase in human heart failure

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7 January 2021

Signaling pathways in cardiac myocyte hypertrophy

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7 January 2021

Coxsackievirus B3 infection leads to cell death of cardiac myocytes

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7 January 2021

Nitroglycerin and delayed preconditioning in humans: yet another new mechanism for an old drug?

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7 January 2021

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

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7 January 2021

Visualisation of cell death in vivo in patients with acute myocardial infarction

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7 January 2021

Nitric oxide modulation of TNF-alpha-induced cardiac contractile dysfunction is concentration dependent.

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7 January 2021

Serum levels of circulating adhesion molecules after coronary angioplasty

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7 January 2021

Tissue expression and immunolocalization of tumor necrosis factor-alpha in postinfarction dysfunctional myocardium

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7 January 2021

Polymorphisms of tumor necrosis factor-alpha and interleukin-10 genes in Japanese patients with idiopathic dilated cardiomyopathy

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7 January 2021

DNA fragmentation and ultrastructural changes of degenerating cells in atherosclerotic lesions and smooth muscle cells exposed to oxidized LDL in vitro.

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7 January 2021

Acute myocardial infarction and increased soluble intercellular adhesion molecule-1: a marker of vascular inflammation and a risk of early restenosis?

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7 January 2021

Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration

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7 January 2021

Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium

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7 January 2021

Biologic therapy for rheumatoid arthritis

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7 January 2021

TNF alpha receptor expression in rat cardiac myocytes: TNF alpha inhibition of L-type Ca2+ current and Ca2+ transients

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7 January 2021

Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice

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7 January 2021

Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha

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7 January 2021

Soluble tumor necrosis factor receptor abrogates myocardial inflammation but not hypertrophy in cytokine-induced cardiomyopathy

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7 January 2021

Overexpression of tumor necrosis factor- alpha activates both anti- and pro-apoptotic pathways in the myocardium

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7 January 2021

Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

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7 January 2021

Prospective randomized trial of corticosteroids for the prevention of restenosis after intracoronary stent implantation

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7 January 2021

Bradykinin-induced preconditioning in patients undergoing coronary angioplasty

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7 January 2021

Delayed preconditioning-mimetic action of nitroglycerin in patients undergoing coronary angioplasty.

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7 January 2021

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure

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7 January 2021

Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation

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7 January 2021

Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

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7 January 2021

Clinical Trials Update: CAPRICORN, COPERNICUS, MIRACLE, STAF, RITZ-2, RECOVER and RENAISSANCE and cachexia and cholesterol in heart failure. Highlights of the Scientific Sessions of the American College of Cardiology, 2001.

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7 January 2021

Characterization of tumor necrosis factor-deficient mice

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7 January 2021

Inflammation in ischemic heart disease: response to tissue injury or a pathogenetic villain?

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7 January 2021

Increased myocardial tumor necrosis factor-alpha in a crystalloid-perfused model of cardiac ischemia-reperfusion injury

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7 January 2021

Human myocardial tissue TNFalpha expression following acute global ischemia in vivo

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7 January 2021

Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury

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7 January 2021

Decreased expression of tumor necrosis factor-alpha and regression of hypertrophy after nonsurgical septal reduction therapy for patients with hypertrophic obstructive cardiomyopathy

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7 January 2021

Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II

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7 January 2021

Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells

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7 January 2021

Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling

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7 January 2021

Irbesartan, an angiotensin type 1 receptor inhibitor, regulates markers of inflammation in patients with premature atherosclerosis

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7 January 2021

Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury

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7 January 2021

Endotoxin and immune activation in chronic heart failure: a prospective cohort study.

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7 January 2021

Accumulation of LDL in rat arteries is associated with activation of tumor necrosis factor-alpha expression

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7 January 2021

Inhibitory effect of troglitazone on tumor necrosis factor alpha-induced expression of monocyte chemoattractant protein-1 in human mesangial cells

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7 January 2021

Effect of beta-blockers on circulating levels of inflammatory and anti-inflammatory cytokines in patients with dilated cardiomyopathy

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7 January 2021

Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling

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7 January 2021

Enhanced angiotensin II activity in heart failure: reevaluation of the counterregulatory hypothesis of receptor subtypes

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7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

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Profound but reversible myocardial depression in patients with septic shock

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Variants of trophic factors and expression of cardiac hypertrophy in patients with hypertrophic cardiomyopathy

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7 January 2021

Cytokines and endothelial cell biology

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7 January 2021

Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

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7 January 2021

Inflammatory markers of coronary risk

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7 January 2021

Interleukin 10 (IL-10)-mediated inhibition of inflammatory cytokine production by human alveolar macrophages

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7 January 2021

Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators

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7 January 2021

Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction

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7 January 2021

Nuclear factor-kappaB is selectively and markedly activated in humans with unstable angina pectoris

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7 January 2021

Preprescription genotyping: not yet ready for prime time, but getting there.

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7 January 2021

Atherosclerosis — An Inflammatory Disease

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7 January 2021

Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity

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7 January 2021

Gene knockout mice as investigative tools in pathophysiology

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7 January 2021

Tumor necrosis factor in myocardial hypertrophy and ischaemia--an anti-apoptotic perspective

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7 January 2021

Expression of tumor necrosis factor-alpha--converting enzyme and tumor necrosis factor-alpha in human myocarditis

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7 January 2021

Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3

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7 January 2021

Basic mechanisms in heart failure: the cytokine hypothesis

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7 January 2021

Beneficial effects of pentoxifylline in patients with idiopathic dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitors and carvedilol: results of a randomized study

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7 January 2021

Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy

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7 January 2021

TNF alpha is required for hypoxia-mediated right ventricular hypertrophy

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7 January 2021

Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis

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7 January 2021

Apoptosis of cardiac myocytes during cardiac allograft rejection. Relation to induction of nitric oxide synthase

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7 January 2021

Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension

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7 January 2021

Ischemic preconditioning in humans: models, mediators, and clinical relevance

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7 January 2021

Expression and Functional Significance of Tumor Necrosis Factor Receptors in Human Myocardium

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7 January 2021

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

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7 January 2021

Shock and tissue injury induced by recombinant human cachectin

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7 January 2021

gp130 plays a critical role in pressure overload-induced cardiac hypertrophy

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7 January 2021

Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6.

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7 January 2021

Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha

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7 January 2021

Cell death induction by TNF: a matter of self control

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7 January 2021

A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate

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7 January 2021

Modulation of coronary vasomotor tone by cytokines in cardiac transplant recipients

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7 January 2021

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

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7 January 2021

Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits

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7 January 2021

Therapeutic effect of anti-tumor necrosis factor-alpha antibody on the murine model of viral myocarditis induced by encephalomyocarditis virus

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7 January 2021

Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation

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7 January 2021

The involvement of cytokines in the second window of ischaemic preconditioning

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7 January 2021

The preconditioning phenomenon: A tool for the scientist or a clinical reality?

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7 January 2021

Ischaemic preconditioning: present position and future directions.

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7 January 2021

Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart

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7 January 2021

Tumor necrosis factor-alpha provokes a hypertrophic growth response in adult cardiac myocytes

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7 January 2021

MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner

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7 January 2021

10.1016/S0163-7258(02)00176-6

Identifiers

DOI

1 reference

4 August 2017

1 reference