(Q34795761)

4 August 2017

1 reference

title

Ketone bodies as a therapeutic for Alzheimer's disease (English)

1 reference

4 August 2017

0 references

Samuel T Henderson

1

1 reference

4 August 2017

publication date

1 July 2008

1 reference

4 August 2017

1 reference

4 August 2017

volume

5

1 reference

4 August 2017

issue

3

1 reference

4 August 2017

page(s)

470-480

1 reference

The brain's default network: anatomy, function, and relevance to disease

4 August 2017

cites work

1 reference

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Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

8 July 2018

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Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies

8 July 2018

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GLUT1 deficiency syndrome--2007 update

8 July 2018

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Cerebral metabolic adaptation and ketone metabolism after brain injury.

8 July 2018

1 reference

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Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Autophagy and neurodegeneration: when the cleaning crew goes on strike

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Neuroprotective and disease-modifying effects of the ketogenic diet

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

D-beta-hydroxybutyrate protects dopaminergic SH-SY5Y cells in a rotenone model of Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Apolipoprotein (apo) E4 and Alzheimer's disease: unique conformational and biophysical properties of apoE4 can modulate neuropathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Early detection of Alzheimer's disease using neuroimaging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Brain work and brain imaging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Axonal transport and Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

The ketogenic diet: from molecular mechanisms to clinical effects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Acetoacetate protects neuronal cells from oxidative glutamate toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

When is a high fat diet not a high fat diet?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Seizure control and acceptance of the ketogenic diet in GLUT1 deficiency syndrome: a 2- to 5-year follow-up of 15 children enrolled prospectively

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Energetic basis of brain activity: implications for neuroimaging.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Increased amyloid- levels in APPSWE transgenic mice treated chronically with a physiological high-fat high-cholesterol diet

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Expression, regulation, and functional role of glucose transporters (GLUTs) in brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Effect of beta-hydroxybutyrate, a cerebral function improving agent, on cerebral hypoxia, anoxia and ischemia in mice and rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Ketone bodies, potential therapeutic uses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Longitudinal SPECT study in Alzheimer's disease: relation to apolipoprotein E polymorphism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Cerebral blood flow and metabolism in schizophrenia. The effects of barbiturate semi-narcosis, insulin coma and electroshock. 1948.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Insulin, ketone bodies, and mitochondrial energy transduction.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Physiological roles of ketone bodies as substrates and signals in mammalian tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Medium-chain triglycerides: an update

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Positron emission tomographic studies of aging and Alzheimer disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Brain Metabolism during Fasting*

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes.

8 July 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

High carbohydrate diets and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

The ketogenic diet increases mitochondrial uncoupling protein levels and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Beta-hydroxybutyrate, a cerebral function improving agent, protects rat brain against ischemic damage caused by permanent and transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Effects of beta-hydroxybutyrate on cognition in memory-impaired adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

The protective effect of a ketogenic diet on kainic acid-induced hippocampal cell death in the male ICR mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

D-beta-hydroxybutyrate is neuroprotective against hypoxia in serum-free hippocampal primary cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Increased cerebral uptake and oxidation of exogenous betaHB improves ATP following traumatic brain injury in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.05.004

Ketone bodies stimulate chaperone-mediated autophagy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084248

Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18625458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apolipoprotein E and Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18625458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased plasma beta-hydroxybutyrate, preserved cerebral energy metabolism, and amelioration of brain damage during neonatal hypoxia ischemia with dexamethasone pretreatment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18625458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NURT.2008.05.004

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference