(Q34797621)

English

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo (English)

1 reference

Europe PubMed Central

4 August 2017

1 reference

based on heuristic

inferred from title

author name string

Q-y Zhu

1

1 reference

Europe PubMed Central

4 August 2017

Z Wang

2

1 reference

Europe PubMed Central

4 August 2017

C Ji

3

1 reference

Europe PubMed Central

4 August 2017

L Cheng

4

1 reference

Europe PubMed Central

4 August 2017

Y-l Yang

5

1 reference

Europe PubMed Central

4 August 2017

J Ren

6

1 reference

Europe PubMed Central

4 August 2017

Y-h Jin

7

1 reference

Europe PubMed Central

4 August 2017

Q-j Wang

8

1 reference

Europe PubMed Central

4 August 2017

X-j Gu

9

1 reference

Europe PubMed Central

4 August 2017

Z-g Bi

10

1 reference

Europe PubMed Central

4 August 2017

G Hu

11

1 reference

Europe PubMed Central

4 August 2017

Y Yang

12

1 reference

Europe PubMed Central

4 August 2017

publication date

27 January 2011

1 reference

Europe PubMed Central

4 August 2017

Cell Death and Disease

1 reference

Europe PubMed Central

4 August 2017

2

1 reference

Europe PubMed Central

4 August 2017

e117

1 reference

Europe PubMed Central

4 August 2017

https://scigraph.springernature.com/pub.10.1038/cddis.2010.96

0 references

Epigenetics and cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Histone deacetylase inhibitors in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Enhancement in anti-proliferative effects of paclitaxel in aortic smooth muscle cells upon co-administration with ceramide using biodegradable polymeric nanoparticles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

New insights on the use of desipramine as an inhibitor for acid ceramidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Protein phosphatase 1 regulates the stability of the circadian protein PER2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Biologically active sphingolipids in cancer pathogenesis and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Ganglioside/glycosphingolipid turnover: new concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Epigenetics in human disease and prospects for epigenetic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Ceramide synthesis and metabolism as a target for cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Worms gang up on bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

HDAC6 is a microtubule-associated deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Histone deacetylases specifically down-regulate p53-dependent gene activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Paclitaxel-induced apoptosis in Jurkat, a leukemic T cell line, is enhanced by ceramide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Signal transduction of stress via ceramide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Ceramide activates heterotrimeric protein phosphatase 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

8 July 2018

Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2010.96

21 January 2018

Metabolism and apoptotic properties of elevated ceramide in HT29rev cells

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2010.96

21 January 2018

Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2010.96

21 January 2018

Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein Tau.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2010.96

21 January 2018

1-phenyl-2-decanoylamino-3-morpholino-1-propanol chemosensitizes neuroblastoma cells for taxol and vincristine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077291

26 October 2018

Modulation of carcinoembryonic antigen release by glucosylceramide. Implications for HT29 cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2010.96

21 January 2018

Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21368888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide

1 reference

https://pubmed.ncbi.nlm.nih.gov/21368888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D3 and ceramide reduce the invasion of tumor cells through extracellular matrix components by elevating protein phosphatase-2A

1 reference

https://pubmed.ncbi.nlm.nih.gov/21368888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fundamental role of epigenetic events in cancer

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2010.96

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CDDIS.2010.96

1 reference

Europe PubMed Central

4 August 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

ResearchGate publication ID

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