(Q34801607)

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O-fucose monosaccharide of Drosophila Notch has a temperature-sensitive function and cooperates with O-glucose glycan in Notch transport and Notch signaling activation

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22 February 2020

O-fucose monosaccharide of Drosophila Notch has a temperature-sensitive function and cooperates with O-glucose glycan in Notch transport and Notch signaling activation (English)

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22 February 2020

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O-fucosyltransferase 1 Dmel_CG12366

1 reference

GOA release 2020-03-11

Rumi Dmel_CG31152

1 reference

GOA release 2020-03-11

Tetsuya Okajima

9

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Europe PubMed Central

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22 February 2020

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Akira Ishio

1

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22 February 2020

Takeshi Sasamura

2

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22 February 2020

Tomonori Ayukawa

3

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22 February 2020

Junpei Kuroda

4

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22 February 2020

Hiroyuki O Ishikawa

5

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22 February 2020

Naoki Aoyama

6

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22 February 2020

Kenjiroo Matsumoto

7

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22 February 2020

Takuma Gushiken

8

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22 February 2020

Tomoko Yamakawa

10

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22 February 2020

Kenji Matsuno

11

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22 February 2020

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5 November 2014

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22 February 2020

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15

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Journal of Biological Chemistry

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22 February 2020

290

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22 February 2020

1

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Europe PubMed Central

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22 February 2020

505-519

1 reference

Europe PubMed Central

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22 February 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4281752/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Negative regulation of notch signaling by xylose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Rescue of Notch signaling in cells incapable of GDP-L-fucose synthesis by gap junction transfer of GDP-L-fucose in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Vertebrate protein glycosylation: diversity, synthesis and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Drosophila Mgr, a Prefoldin subunit cooperating with von Hippel Lindau to regulate tubulin stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Structural Insights into the Mechanism of Protein O-Fucosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Chemical synthesis, folding, and structural insights into O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Endocytic internalization routes required for delta/notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Notch signaling: the core pathway and its posttranslational regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

The canonical Notch signaling pathway: unfolding the activation mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Roles of Pofut1 and O-fucose in mammalian Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Notch signalling: a simple pathway becomes complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Notch deficiency implicated in the pathogenesis of congenital disorder of glycosylation IIc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

O-fucosylation of notch occurs in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Multiple niches for Notch in cancer: context is everything

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Glycosylation regulates Notch signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Notch signaling and inherited disease syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Ends-out, or replacement, gene targeting in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Fringe is a glycosyltransferase that modifies Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Notch signaling: cell fate control and signal integration in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

The metabolism of 6-deoxyhexoses in bacterial and animal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Multiple roles for notch in Drosophila myogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Purification and characterization of a GDP-fucose:polypeptide fucosyltransferase from Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Fringe modulates Notch-ligand interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Analysis of genetic mosaics in developing and adult Drosophila tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Dual functions of wingless in the Drosophila leg imaginal disc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Patterns of expression of cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

8 July 2018

Mammalian Notch is modified by D-Xyl-alpha1-3-D-Xyl-alpha1-3-D-Glc-beta1-O-Ser: implementation of a method to study O-glucosylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

O-linked N-acetylglucosamine is present on the extracellular domain of notch receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Regulation of notch signaling by o-linked fucose.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

The O-fucosyltransferase O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Polarized exocytosis and transcytosis of Notch during its apical localization in Drosophila epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila Leg.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

The interplay between DSL proteins and ubiquitin ligases in Notch signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Location matters: the endoplasmic reticulum and protein trafficking in dendrites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.616847

21 January 2018

Cell proliferation control by Notch signaling in Drosophila development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

26 October 2018

Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

26 October 2018

Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281752

26 October 2018

The balance between GMD and OFUT1 regulates Notch signaling pathway activity by modulating Notch stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/25378397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene targeting by homologous recombination in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/25378397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fringe-dependent separation of dorsal and ventral cells in the Drosophila wing

1 reference

https://pubmed.ncbi.nlm.nih.gov/25378397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.616847

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378397%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378397%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378397%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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