(Q34802735)

4 August 2017

title

Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity (English)

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4 August 2017

Sang Seop Lee

1

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4 August 2017

Eun-Young Cha

2

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4 August 2017

Hyun-Ju Jung

3

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4 August 2017

Ji-Hong Shon

4

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4 August 2017

Eun-Young Kim

5

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4 August 2017

Chang-Woo Yeo

6

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4 August 2017

Jae-Gook Shin

7

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4 August 2017

language of work or name

English

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publication date

1 August 2008

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4 August 2017

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4 August 2017

volume

48

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4 August 2017

issue

2

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4 August 2017

page(s)

635-645

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The influence of enzyme induction on polymorphic sparteine oxidation

4 August 2017

cites work

1 reference

Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth.

21 January 2018

1 reference

7 January 2021

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion

1 reference

7 January 2021

Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences

1 reference

7 January 2021

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

1 reference

7 January 2021

Transcriptional Activation of CYP2C9, CYP1A1, and CYP1A2 by Hepatocyte Nuclear Factor 4 Requires Coactivators Peroxisomal Proliferator Activated Receptor- Coactivator 1 and Steroid Receptor Coactivator 1

1 reference

7 January 2021

Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha

1 reference

7 January 2021

Transcriptional regulation of human CYP2C genes: functional comparison of CYP2C9 and CYP2C18 promoter regions

1 reference

7 January 2021

Characterization of the human cytochrome P4502D6 promoter. A potential role for antagonistic interactions between members of the nuclear receptor family

1 reference

7 January 2021

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

1 reference

7 January 2021

The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4alpha on the disposition of debrisoquine in the mouse.

1 reference

7 January 2021

Pharmacogenetics of the major polymorphic metabolizing enzymes.

1 reference

7 January 2021

Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity

1 reference

7 January 2021

Genetic polymorphism of CYP2C9 in a Vietnamese Kinh population

1 reference

7 January 2021

Haploview: analysis and visualization of LD and haplotype maps

1 reference

7 January 2021

Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity

1 reference

7 January 2021

Evaluation of probe drugs and pharmacokinetic metrics for CYP2D6 phenotyping

1 reference

7 January 2021

Determination of dextromethorphan and dextrorphan in human plasma by liquid chromatography/tandem mass spectrometry

1 reference

7 January 2021

High performance liquid chromatography determination of dextromethorphan and its metabolites in urine using solid-phase extraction.

1 reference

7 January 2021

Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA

1 reference

7 January 2021

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

1 reference

7 January 2021

Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

1 reference

7 January 2021

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

1 reference

7 January 2021

Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients

1 reference

7 January 2021

The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes.

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.22396

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release_dcrui2orebe2vax5e6a4vtz5oi

4 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dcrui2orebe2vax5e6a4vtz5oi

24 November 2022

mapped directly with Wikidata item

1 reference