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Calmodulin binds HER2 and modulates HER2 signaling
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Europe PubMed Central
PMCID
3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
title
Calmodulin binds HER2 and modulates HER2 signaling
(English)
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Europe PubMed Central
PMCID
3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
author
David B. Sacks
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3
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Europe PubMed Central
PMCID
3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
author name string
Colin D White
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1
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Europe PubMed Central
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3079001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
Zhigang Li
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2
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3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
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18 January 2020
language of work or name
English
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publication date
24 December 2010
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Europe PubMed Central
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18 January 2020
published in
Biochimica et Biophysica Acta
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Europe PubMed Central
PMCID
3079001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
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18 January 2020
volume
1813
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Europe PubMed Central
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3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
issue
5
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Europe PubMed Central
PMCID
3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
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1074-1082
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Europe PubMed Central
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3079001
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
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18 January 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3079001/fullTextXML
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PubMed Central
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The ErbB2/Neu/HER2 receptor is a new calmodulin-binding protein.
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The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors
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Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
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Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?
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Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1
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The conformational plasticity of protein kinases
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Evidence for the direct interaction between calmodulin and the human epidermal growth factor receptor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins.
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8 July 2018
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin
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8 July 2018
Calmodulin enhances the stability of the estrogen receptor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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8 July 2018
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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8 July 2018
Ca(2+)-dependent and Ca(2+)-independent calmodulin binding sites in erythrocyte protein 4.1. Implications for regulation of protein 4.1 interactions with transmembrane proteins
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8 July 2018
Apocalmodulin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site.
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Ca2+-independent inhibition of inositol trisphosphate receptors by calmodulin: redistribution of calmodulin as a possible means of regulating Ca2+ mobilization
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8 July 2018
Sequence motifs for calmodulin recognition
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8 July 2018
Tyrosine-specific phosphorylation of calmodulin by the insulin receptor kinase purified from human placenta
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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8 July 2018
Ligand-induced functions of the epidermal growth factor receptor require the positively charged region asymmetrically distributed across plasma membrane
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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8 July 2018
Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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26 October 2018
Activated Akt signaling pathway in invasive ductal carcinoma of the breast: correlation with HER2 overexpression.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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26 October 2018
Phosphorylation of Thr654 but not Thr669 within the juxtamembrane domain of the EGF receptor inhibits calmodulin binding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
retrieved
26 October 2018
Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
retrieved
26 October 2018
A basic peptide within the juxtamembrane region is required for EGF receptor dimerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
retrieved
26 October 2018
Interactions between the juxtamembrane domain of the EGFR and calmodulin measured by surface plasmon resonance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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26 October 2018
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
retrieved
26 October 2018
Synergistic induction of apoptosis in breast cancer cells by tamoxifen and calmodulin inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
retrieved
26 October 2018
CGS 9343B, a novel, potent, and selective inhibitor of calmodulin activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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26 October 2018
Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
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26 October 2018
In VitroInteraction of Estradiol Receptor with Ca2+-Calmodulin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079001
retrieved
9 December 2018
Antagonistic effect of triphenylethylenic antiestrogens on the association of estrogen receptor to calmodulin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The juxtamembrane region of the epidermal growth factor receptor is required for phosphorylation of Galpha(s)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The insulin receptor contains a calmodulin-binding domain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Calmodulin inhibits the epidermal growth factor receptor tyrosine kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Estradiol derivatives bearing the side-chain of tamoxifen antagonize the association between the estrogen receptor and calmodulin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective inhibition of HER2 inhibits AKT signal transduction and prolongs disease-free survival in a micrometastasis model of ovarian carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21185879
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBAMCR.2010.12.016
1 reference
stated in
Europe PubMed Central
PMCID
3079001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PMCID
3079001
1 reference
stated in
Europe PubMed Central
PMCID
3079001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PubMed ID
21185879
1 reference
stated in
Europe PubMed Central
PMCID
3079001
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21185879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
ResearchGate publication ID
49709457
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