(Q34811742)

4 August 2017

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title

Studies of biomolecular conformations and conformational dynamics by mass spectrometry (English)

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4 August 2017

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Igor A Kaltashov

1

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PubMed ID

12210613

4 August 2017

Stephen J Eyles

series ordinal

2

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4 August 2017

1 January 2002

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Mass Spectrometry Reviews

4 August 2017

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4 August 2017

21

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4 August 2017

37-71

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4 August 2017

1

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PubMed ID

12210613

describes a project that uses

4 August 2017

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Characterization of the interface structure of enzyme-inhibitor complex by using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

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Pulsed-alkylation mass spectrometry for the study of protein folding and dynamics: development and application to the study of a folding/unfolding intermediate of bacterial luciferase

21 January 2018

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21 January 2018

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A new crosslinker for mass spectrometric analysis of the quaternary structure of protein complexes

21 January 2018

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Primary structure effects on peptide group hydrogen exchange

21 January 2018

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Protein folding intermediates: native-state hydrogen exchange

21 January 2018

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Solution structure and dynamics of biomolecules from Raman optical activity.

21 January 2018

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Chemical cross-linking with thiol-cleavable reagents combined with differential mass spectrometric peptide mapping--a novel approach to assess intermolecular protein contacts

21 January 2018

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Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry

21 January 2018

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Solvent effects on the conformation of the transmembrane peptide gramicidin A: insights from electrospray ionization mass spectrometry

21 January 2018

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21 January 2018

Conformational disease

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Touring the landscapes: partially folded proteins examined by hydrogen exchange

21 January 2018

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Examining the conformational dynamics of macromolecules with time-resolved synchrotron X-ray ‘footprinting’

21 January 2018

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Folding of malate dehydrogenase inside the GroEL-GroES cavity

21 January 2018

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Ultraviolet resonance Raman examination of horse apomyoglobin acid unfolding intermediates.

21 January 2018

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Intrinsic tryptophans of CRABPI as probes of structure and folding

21 January 2018

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Local breathing and global unfolding in hydrogen exchange of barnase and its relationship to protein folding pathways

21 January 2018

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An evaluation of the use of hydrogen exchange at equilibrium to probe intermediates on the protein folding pathway

21 January 2018

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Hydrogen exchange at equilibrium: a short cut for analysing protein-folding pathways?

21 January 2018

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On the use of chemically derived distance constraints in the prediction of protein structure with myoglobin as an example

21 January 2018

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Some tenets pertaining to electrospray ionization mass spectrometry

21 January 2018

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beta -Helical polymers from isocyanopeptides

21 January 2018

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Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.

21 January 2018

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Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry

21 January 2018

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From Levinthal to pathways to funnels

21 January 2018

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Understanding protein folding via free-energy surfaces from theory and experiment

21 January 2018

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Detection of multiple protein conformational ensembles in solution via deconvolution of charge-state distributions in ESI MS.

21 January 2018

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Understanding how proteins fold: the lysozyme story so far.

21 January 2018

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Is Apomyoglobin a Molten Globule? Structural Characterization by NMR

21 January 2018

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Protein hydrogen exchange studied by the fragment separation method.

21 January 2018

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Structure and energy change in hemoglobin by hydrogen exchange labeling

21 January 2018

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Hydrogen exchange: the modern legacy of Linderstrøm-Lang

21 January 2018

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Protein folding intermediates and pathways studied by hydrogen exchange

21 January 2018

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Observation of the noncovalent assembly and disassembly pathways of the chaperone complex MtGimC by mass spectrometry

21 January 2018

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Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy

21 January 2018

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Identification of the binding surface on beta-lactamase for GroEL by limited proteolysis and MALDI-mass spectrometry

21 January 2018

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Structures of apomyoglobin's various acid-destabilized forms

21 January 2018

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Perspectives for mass spectrometry and functional proteomics

21 January 2018

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Significant hydrogen exchange protection in GroEL-bound DHFR is maintained during iterative rounds of substrate cycling

21 January 2018

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Dynamics of iron release from transferrin N-lobe studied by electrospray ionization mass spectrometry

21 January 2018

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The palmitoyl groups of lung surfactant protein C reduce unfolding into a fibrillogenic intermediate

21 January 2018

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Mass spectrometry and proteomics

21 January 2018

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Selective bridging of bis-cysteinyl residues by arsonous acid derivatives as an approach to the characterization of protein tertiary structures and folding pathways by mass spectrometry

21 January 2018

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Evidence for an obligatory intermediate in the folding of interleukin-1 beta

21 January 2018

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Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange

21 January 2018

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Kinetic intermediates in the folding of gaseous protein ions characterized by electron capture dissociation mass spectrometry

21 January 2018

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Phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of methylesterase CheB.

21 January 2018

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Evidence for identity between the equilibrium unfolding intermediate and a transient folding intermediate: a comparative study of the folding reactions of alpha-lactalbumin and lysozyme

21 January 2018

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Direct evidence by H/D exchange and ESI-MS for transient unproductive domain interaction in the refolding of an antibody scFv fragment

21 January 2018

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Conformational changes in proteins probed by hydrogen-exchange electrospray-ionization mass spectrometry

21 January 2018

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Site-specific amide hydrogen/deuterium exchange in E. coli thioredoxins measured by electrospray ionization mass spectrometry.

21 January 2018

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Acid-induced denaturation of myoglobin studied by time-resolved electrospray ionization mass spectrometry.

21 January 2018

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Equilibrium unfolding of proteins monitored by electrospray ionization mass spectrometry: distinguishing two-state from multi-state transitions

21 January 2018

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Characterization of intermolecular beta-sheet peptides by mass spectrometry and hydrogen isotope exchange

21 January 2018

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Dynamics of cellular retinoic acid binding protein I on multiple time scales with implications for ligand binding

21 January 2018

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Reconstitution of acid-denatured holomyoglobin studied by time-resolved electrospray ionization mass spectrometry.

21 January 2018

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Antiviral agent blocks breathing of the common cold virus.

21 January 2018

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Infrared multiphoton dissociation of large multiply charged ions for biomolecule sequencing

21 January 2018

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The energetics of T4 lysozyme reveal a hierarchy of conformations

21 January 2018

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Solvent-induced conformational changes of polypeptides probed by electrospray-ionization mass spectrometry

21 January 2018

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Studying noncovalent protein complexes by electrospray ionization mass spectrometry

21 January 2018

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Millisecond radiolytic modification of peptides by synchrotron X-rays identified by mass spectrometry

21 January 2018

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Electrospray-assisted modification of proteins: a radical probe of protein structure.

21 January 2018

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Determination of macromolecular folding and structure by synchrotron x-ray radiolysis techniques.

21 January 2018

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Measurement of amide hydrogen exchange by MALDI-TOF mass spectrometry

21 January 2018

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Solvent accessibility of the thrombin-thrombomodulin interface

21 January 2018

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Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance

21 January 2018

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Detection of transient protein folding populations by mass spectrometry

21 January 2018

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Protein complexes and analysis of their assembly by mass spectrometry

21 January 2018

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Isotope-tagged cross-linking reagents. A new tool in mass spectrometric protein interaction analysis

21 January 2018

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Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium.

21 January 2018

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Characterization of the oligomeric states of insulin in self-assembly and amyloid fibril formation by mass spectrometry

21 January 2018

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Theory of protein folding: the energy landscape perspective

21 January 2018

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A kinetic folding intermediate probed by native state hydrogen exchange

21 January 2018

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Spectroscopic methods for analysis of protein secondary structure

21 January 2018

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Molecular structures from low angle X-ray and neutron scattering studies

21 January 2018

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Measurements of protein stability by H/D exchange and matrix-assisted laser desorption/ionization mass spectrometry using picomoles of material

21 January 2018

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Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method

21 January 2018

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Conformational issues in the characterization of proteins

21 January 2018

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Kinetic and equilibrium intermediates in protein folding

21 January 2018

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From computer simulations to human disease: emerging themes in protein folding

21 January 2018

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A generic strategy to analyze the spatial organization of multi-protein complexes by cross-linking and mass spectrometry.

21 January 2018

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Modeling deuterium exchange behavior of ERK2 using pepsin mapping to probe secondary structure.

21 January 2018

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Conformation of GroEL-bound alpha-lactalbumin probed by mass spectrometry.

21 January 2018

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Protein folding kinetics by combined use of rapid mixing techniques and NMR observation of individual amide protons

21 January 2018

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An experimental procedure for increasing the structural resolution of chemical hydrogen-exchange measurements on proteins: Application to ribonuclease S peptide

21 January 2018

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Disassembly of intact multiprotein complexes in the gas phase

21 January 2018

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Detection and selective dissociation of intact ribosomes in a mass spectrometer

21 January 2018

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On the maximum charge state and proton transfer reactivity of peptide and protein ions formed by electrospray ionization

21 January 2018

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Different subdomains are most protected from hydrogen exchange in the molten globule and native states of human alpha-lactalbumin

21 January 2018

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Time-resolved synchrotron X-ray "footprinting", a new approach to the study of nucleic acid structure and function: application to protein-DNA interactions and RNA folding.

21 January 2018

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The renaissance of fluorescence resonance energy transfer

21 January 2018

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Probing the non-covalent structure of proteins by amide hydrogen exchange and mass spectrometry

21 January 2018

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The concept of a random coil. Residual structure in peptides and denatured proteins

21 January 2018

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Effects of pH on the kinetic reaction mechanism of myoglobin unfolding studied by time-resolved electrospray ionization mass spectrometry.

21 January 2018

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Protein surface topology-probing by selective chemical modification and mass spectrometric peptide mapping.

21 January 2018

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Absence of stable intermediates on the folding pathway of barnase

21 January 2018

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How common is the funnel-like energy landscape in protein-protein interactions?

21 January 2018

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Protein folding via binding and vice versa.

21 January 2018

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Folding funnels, binding funnels, and protein function

21 January 2018

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Quench-flow experiments combined with mass spectrometry show apomyoglobin folds through and obligatory intermediate

21 January 2018

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Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsids

21 January 2018

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Deuterium exchange of alpha-helices and beta-sheets as monitored by electrospray ionization mass spectrometry

21 January 2018

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A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase

21 January 2018

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Detecting structural changes in viral capsids by hydrogen exchange and mass spectrometry

21 January 2018

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Trapping of intermediates during the refolding of recombinant human epidermal growth factor (hEGF) by cyanylation, and subsequent structural elucidation by mass spectrometry

21 January 2018

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A novel methodology for assignment of disulfide bond pairings in proteins

21 January 2018

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Optimization of the cleavage reaction for cyanylated cysteinyl proteins for efficient and simplified mass mapping

21 January 2018

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High throughput protein fold identification by using experimental constraints derived from intramolecular cross-links and mass spectrometry.

21 January 2018

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Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

21 January 2018

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In vivo formation of allosteric aspartate transcarbamoylase containing circularly permuted catalytic polypeptide chains: implications for protein folding and assembly

21 January 2018

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Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process

21 January 2018

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Cavity formation before stable hydrogen bonding in the folding of a β-clam protein

21 January 2018

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Two conformational states of β-lactamase bound to GroEL: a biophysical characterization 1 1Edited by A. R. Fersht

21 January 2018

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Advantages of External Accumulation for Electron Capture Dissociation in Fourier Transform Mass Spectrometry

21 January 2018

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Origin of the Absorption Band at 1,550 cm.−1 in Proteins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MAS.10017

1 reference

4 August 2017

1 reference

PubMed ID

12210613