(Q34829321)

4 August 2017

Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes (English)

1 reference

4 August 2017

0 references

D Amsen

1

1 reference

4 August 2017

C Revilla Calvo

series ordinal

2

1 reference

4 August 2017

B A Osborne

series ordinal

3

1 reference

4 August 2017

A M Kruisbeek

series ordinal

4

1 reference

4 August 2017

language of work or name

English

0 references

publication date

1 January 1999

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

1 reference

4 August 2017

96

1 reference

4 August 2017

622-627

1 reference

4 August 2017

2

1 reference

Impaired negative selection in CD28-deficient mice.

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Positive selection of T cells: fastidious or promiscuous?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Positive selection of thymocytes bearing alpha beta T cell receptors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Apoptosis by death factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Induction of the early growth response (Egr) family of transcription factors during thymic selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Negative selection in the thymus includes semimature T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

CD28-B7 interactions function to co-stimulate clonal deletion of double-positive thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

T cell receptor antagonist peptides induce positive selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Intrathymic and extrathymic tolerance in bone marrow chimeras

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Involvement of p21ras distinguishes positive and negative selection in thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Differential T cell costimulatory requirements in CD28-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Positive selection of thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

An essential role for gp39, the ligand for CD40, in thymic selection.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Deletion of high-avidity T cells by thymic epithelium

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Identification of a monoclonal antibody specific for a murine T3 polypeptide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Positive selection of CD4+ T cells mediated by MHC class II-bearing stromal cell in the thymic cortex.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Positive selection of the T cell repertoire: where and when does it occur?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Transactivation by AP-1 is a molecular target of T cell clonal anergy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Deletion of antigen-specific immature thymocytes by dendritic cells requires LFA-1/ICAM interactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Identification and distribution of the costimulatory receptor CD28 in the mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Selective requirement for MAP kinase activation in thymocyte differentiation.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Thymic expression of the transcription factor Nur77 rescues the T cell but not the B cell abnormality of gld/gld mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Identification of an alternative CTLA-4 ligand costimulatory for T cell activation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Two signals are required for negative selection of CD4+CD8+ thymocytes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15186

Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Raf regulates positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Alternative pathways for the selection of antigen-specific peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Positive and negative thymocyte selection induced by different concentrations of a single peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.2.622

Identity of cells that imprint H-2-restricted T-cell specificity in the thymus

21 January 2018

1 reference

12 December 2020

B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes

1 reference

12 December 2020

Clonal deletion of V beta 5+ T cells by transgenic I-E restricted to thymic medullary epithelium

1 reference

12 December 2020

CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance

1 reference

12 December 2020

Induction of thymocyte deletion by purified single peptide/major histocompatibility complex ligands

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.2.622

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference