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The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

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scholarly article

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Europe PubMed Central

4 August 2017

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Europe PubMed Central

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis (English)

1 reference

Europe PubMed Central

4 August 2017

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Alzheimer's disease

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multiple sclerosis

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1 reference

based on heuristic

inferred from title

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author name string

Alireza Minagar

1

1 reference

Europe PubMed Central

4 August 2017

Paul Shapshak

2

1 reference

Europe PubMed Central

4 August 2017

Robert Fujimura

3

1 reference

Europe PubMed Central

4 August 2017

Ray Ownby

4

1 reference

Europe PubMed Central

4 August 2017

Melvin Heyes

5

1 reference

Europe PubMed Central

4 August 2017

Carl Eisdorfer

6

1 reference

Europe PubMed Central

4 August 2017

publication date

1 October 2002

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Europe PubMed Central

4 August 2017

number of pages

11

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inferred from page(s)

Journal of the Neurological Sciences

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Europe PubMed Central

4 August 2017

202

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Europe PubMed Central

4 August 2017

1-2

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Europe PubMed Central

4 August 2017

13-23

1 reference

Europe PubMed Central

4 August 2017

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

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7 January 2021

Cytotoxicity of microglia

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7 January 2021

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7 January 2021

Microglia: Intrinsic immuneffector cell of the brain

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7 January 2021

Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

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Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells.

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MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by gamma-interferon

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7 January 2021

B7/BB-1 antigen expression on adult human microglia studied in vitro and in situ

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7 January 2021

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

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Interactions of the nervous and immune systems in development, normal brain homeostasis, and disease.

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Epidemiology of human immunodeficiency virus encephalopathy in the United States

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The AIDS dementia complex: I. Clinical features

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AIDS dementia complex with generalized myoclonus.

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Paroxysmal dyskinesias in patients with HIV infection.

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Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature

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Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study.

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Early penetration of the blood-brain-barrier by HIV.

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Macrophage Activation Factors in the Brains of AIDS Patients

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Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebrospinal fluid during acute and chronic infection

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Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome.

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Patterns of neurodegeneration in HIV encephalitis

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Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

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Pathology of HIV-1 infection of the central nervous system. A review

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

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The macrophage in the persistence and pathogenesis of HIV infection

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Early viral brain invasion in iatrogenic human immunodeficiency virus infection

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Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia

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Cytokine expression in the brain during the acquired immunodeficiency syndrome

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Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

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AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines.

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Nitric oxide: first in a new class of neurotransmitters

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Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

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7 January 2021

Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients

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Increased ratio of quinolinic acid to kynurenic acid in cerebrospinal fluid of D retrovirus-infected rhesus macaques: relationship to clinical and viral status.

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Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome

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7 January 2021

Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms

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Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease

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7 January 2021

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

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Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry.

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7 January 2021

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

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7 January 2021

Induction of tryptophan degradation in vitro and in vivo: a gamma-interferon-stimulated activity

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7 January 2021

Negative correlation between blood cell counts and serum neopterin concentration in patients with HIV-1 infection

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7 January 2021

Human macrophages degrade tryptophan upon induction by interferon-gamma

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Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes

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7 January 2021

Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues.

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7 January 2021

HIV-1 infection of subcortical astrocytes in the pediatric central nervous system.

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7 January 2021

Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry

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7 January 2021

Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry

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7 January 2021

Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia.

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7 January 2021

Restricted expression of HIV1 in human astrocytes: molecular basis for viral persistence in the CNS.

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Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways

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7 January 2021

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases

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7 January 2021

Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis

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7 January 2021

Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human neurons

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Human Astrocytes Stimulate HIV-1 Expression in a Chronically Infected Promonocyte Clone via Interleukin-6

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7 January 2021

Cytokines and the nervous system. I: Expression and recognition

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TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier.

1 reference

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7 January 2021

The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid

1 reference

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7 January 2021

Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia

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7 January 2021

Overexpression of nerve growth factor and basic fibroblast growth factor in AIDS dementia complex.

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7 January 2021

Free radicals induce gene expression of NGF and bFGF in rat astrocyte culture

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7 January 2021

bFGF and FGFR-3 immunoreactivity in the rat brain following systemic kainic acid administration at convulsant doses: localization of bFGF and FGFR-3 in reactive astrocytes, and FGFR-3 in reactive microglia.

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7 January 2021

Astrocytes in infectious and immune-mediated diseases of the central nervous system.

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7 January 2021

Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine

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7 January 2021

Alzheimer's disease: genotypes, phenotypes, and treatments

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities

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7 January 2021

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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7 January 2021

Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity

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7 January 2021

Notch and presenilins in vertebrates and invertebrates: implications for neuronal development and degeneration

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7 January 2021

Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain.

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7 January 2021

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

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7 January 2021

The role of the immune system in neurodegenerative disorders

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7 January 2021

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

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7 January 2021

beta-Amyloid induces increased release of interleukin-1 beta from lipopolysaccharide-activated human monocytes

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7 January 2021

Interaction of Alzheimer beta-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha

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7 January 2021

beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate

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7 January 2021

Activation of macrophages by Alzheimer beta amyloid peptide.

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7 January 2021

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

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7 January 2021

Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function.

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7 January 2021

Specific domains of beta-amyloid from Alzheimer plaque elicit neuron killing in human microglia.

1 reference

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7 January 2021

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

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7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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7 January 2021

Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways

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7 January 2021

Activation of nuclear factor-kappa B by beta-amyloid peptides and interferon-gamma in murine microglia

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7 January 2021

Inflammatory Signals Induce Neurotrophin Expression in Human Microglial Cells

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7 January 2021

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

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7 January 2021

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

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7 January 2021

Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease

1 reference

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7 January 2021

Glial-derived proteins activate cultured astrocytes and enhance beta amyloid-induced glial activation.

1 reference

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7 January 2021

Redox regulation of lipopolysaccharide (LPS)-induced interleukin-8 (IL-8) gene expression mediated by NF kappa B and AP-1 in human astrocytoma U373 cells.

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7 January 2021

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

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7 January 2021

Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release.

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7 January 2021

Selective killing of cholinergic neurons by microglial activation in basal forebrain mixed neuronal/glial cultures.

1 reference

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7 January 2021

Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: a role for transforming growth factor beta

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7 January 2021

Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease.

1 reference

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7 January 2021

Is there a balance between microglia and astrocytes in regulating Th1/Th2-cell responses and neuropathologies?

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7 January 2021

The adhesion molecule and cytokine profile of multiple sclerosis lesions

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7 January 2021

CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

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7 January 2021

Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines

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7 January 2021

Induction of primary T cell responses by human glial cells

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7 January 2021

Inducible expression of H-2 and Ia antigens on brain cells.

1 reference

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7 January 2021

Human astrocytes are only partially competent antigen presenting cells. Possible implications for lesion development in multiple sclerosis.

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7 January 2021

Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells

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7 January 2021

T cell subsets in multiple sclerosis. Gradients at plaque borders and differences in nonplaque regions.

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7 January 2021

On classification of post-mortem multiple sclerosis plaques for neuroscientists.

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7 January 2021

Nature of the reversible white matter lesion in multiple sclerosis. Effects of acute inflammation on myelinated tissue studied in the rabbit eye

1 reference

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7 January 2021

Dual implication of 2',3'-cyclic nucleotide 3' phosphodiesterase as major autoantigen and C3 complement-binding protein in the pathogenesis of multiple sclerosis

1 reference

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7 January 2021

Microglia induce CD4 T lymphocyte final effector function and death

1 reference

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7 January 2021

Astrocytes promote process outgrowth by adult human oligodendrocytes in vitro through interaction between bFGF and astrocyte extracellular matrix

1 reference

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7 January 2021

Interleukin-4 and -5 as modulators of nerve growth factor synthesis/secretion in astrocytes

1 reference

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7 January 2021

Apoptosis of inflammatory cells in immune control of the nervous system: role of glia

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7 January 2021

Microglial phagocytosis is modulated by pro- and anti-inflammatory cytokines.

1 reference

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7 January 2021

Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis

1 reference

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7 January 2021

The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The neurobiology of human immunodeficiency virus infections

1 reference

https://api.crossref.org/works/10.1016%2FS0022-510X%2802%2900207-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain macrophages: neurotoxic or neurotrophic effector cells?

1 reference

https://api.crossref.org/works/10.1016%2FS0022-510X%2802%2900207-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Innate and acquired immunity in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0022-510X%2802%2900207-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of microglia in plaque formation in senile dementia of the Alzheimer type. An immunohistochemical study.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-510X%2802%2900207-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ultrastructural studies of the cells forming amyloid fibers in classical plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-510X%2802%2900207-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-1 beta and tumor necrosis factor-alpha induce expression of alpha 1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-kappa B.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0022-510X(02)00207-1

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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