(Q34835690)

4 August 2017

title

Impact of gene expression noise on organismal fitness and the efficacy of natural selection (English)

1 reference

4 August 2017

Zhi Wang

1

1 reference

4 August 2017

Jianzhi Zhang

series ordinal

2

1 reference

4 August 2017

language of work or name

English

0 references

publication date

4 April 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

108

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4 August 2017

issue

16

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4 August 2017

page(s)

E67-76

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Impact of translational error-induced and error-free misfolding on the rate of protein evolution

4 August 2017

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Living with noisy genes: how cells function reliably with inherent variability in gene expression

8 July 2018

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8 July 2018

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Plasticity of genetic interactions in metabolic networks of yeast

8 July 2018

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8 July 2018

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8 July 2018

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Increased cell-to-cell variation in gene expression in ageing mouse heart

8 July 2018

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Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

8 July 2018

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Chance and necessity in the evolution of minimal metabolic networks

8 July 2018

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Transcriptional noise and cellular heterogeneity in mammalian macrophages

8 July 2018

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Origins of extrinsic variability in eukaryotic gene expression

8 July 2018

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Noise in gene expression: origins, consequences, and control

8 July 2018

1 reference

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Stochasticity in gene expression: from theories to phenotypes

8 July 2018

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Noise propagation in gene networks

8 July 2018

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Gene regulation at the single-cell level

8 July 2018

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Genome-scale models of microbial cells: evaluating the consequences of constraints

8 July 2018

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Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model

8 July 2018

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Control of stochasticity in eukaryotic gene expression

8 July 2018

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Noise minimization in eukaryotic gene expression

8 July 2018

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Summing up the noise in gene networks

8 July 2018

1 reference

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Flux coupling analysis of genome-scale metabolic network reconstructions.

8 July 2018

1 reference

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Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Dosage sensitivity and the evolution of gene families in yeast

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Increased noise as an effect of haploinsufficiency of the tumor-suppressor gene neurofibromatosis type 1 in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Stochastic gene expression in a single cell

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Systematic screen for human disease genes in yeast

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Metabolic modelling of microbes: the flux-balance approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Regulation of noise in the expression of a single gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Engineering stability in gene networks by autoregulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

The molecular basis of dominance.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Natural selection for within-generation variance in offspring number II. Discrite haploid models

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Stochastic switching as a survival strategy in fluctuating environments

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Evolution of chromosome organization driven by selection for reduced gene expression noise

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Adaptive evolution of bacterial metabolic networks by horizontal gene transfer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Metabolic gene-deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Large-scale evaluation of in silico gene deletions in Saccharomyces cerevisiae

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080991

Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast

26 October 2018

1 reference

12 December 2020

Effects on phenotypic variability of directional selection arising through genetic differences in residual variability

1 reference

12 December 2020

Energy costs constrain the evolution of gene expression

1 reference

12 December 2020

Energy constraints on the evolution of gene expression

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1100059108

1 reference

4 August 2017

0 references

1 reference

4 August 2017

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