(Q34880830)

5 August 2017

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title

Benefit and risks of local anesthetics in infants and children (English)

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5 August 2017

Joel B Gunter

1

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5 August 2017

1 January 2002

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5 August 2017

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5 August 2017

4

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5 August 2017

10

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5 August 2017

649-672

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https://scigraph.springernature.com/pub.10.2165/00128072-200204100-00003

5 August 2017

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cites work

Continuous extrapleural paravertebral infusion of bupivacaine for post-thoracotomy analgesia in young infants

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Ropivacaine in children.

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Comparison of ropivacaine with bupivacaine for paediatric caudal block.

21 January 2018

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Caudal anaesthesia with 0.375% ropivacaine or 0.375% bupivacaine in paediatric patients.

21 January 2018

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Pharmacokinetics of the enantiomers of bupivacaine following intravenous administration of the racemate

21 January 2018

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Comparison of S(-)-bupivacaine with racemic (RS)-bupivacaine in supraclavicular brachial plexus block.

21 January 2018

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Extradural S(-)-bupivacaine: comparison with racemic RS-bupivacaine.

21 January 2018

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Accidents following extradural analgesia in children. The results of a retrospective study

21 January 2018

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12 December 2020

Continuous paravertebral block in children. Initial experience

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12 December 2020

Transient neurologic toxicity after hyperbaric subarachnoid anesthesia with 5% lidocaine

1 reference

12 December 2020

Toxicological and local anaesthetic effects of optically active isomers of two local anaesthetic compounds.

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12 December 2020

Local anesthetic serum concentrations after penile nerve block in children

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12 December 2020

Continuous extradural anaesthesia in children. Clinical and haemodynamic implications.

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12 December 2020

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12 December 2020

Low-dose lidocaine intravenous regional anesthesia for forearm fractures in children

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12 December 2020

Caudal analgesia: a simple and safe technique in paediatric surgery.

1 reference

12 December 2020

Efficacy of an epidural test dose in children anesthetized with halothane.

1 reference

12 December 2020

Percutaneous inguinal block for the outpatient management of post-herniorrhaphy pain in children.

1 reference

12 December 2020

Detection of intravascular injection of regional anaesthetics in children.

1 reference

12 December 2020

Modern concepts of paediatric analgesia

1 reference

12 December 2020

Cardiovascular collapse in an infant after caudal anesthesia with a lidocaine-epinephrine solution.

1 reference

12 December 2020

1 reference

12 December 2020

Clonidine-mepivacaine mixture vs plain mepivacaine in paediatric surgery.

1 reference

12 December 2020

Femoral nerve blockade in children using bupivacaine.

1 reference

12 December 2020

Postoperative apnea, bradycardia, and oxygen desaturation in formerly premature infants: prospective comparison of spinal and general anesthesia.

1 reference

12 December 2020

Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers

1 reference

12 December 2020

Toxicity of bupivacaine and ropivacaine in relation to free plasma concentrations in pregnant rats: a comparative study.

1 reference

12 December 2020

Pharmacokinetics and cardiovascular effects of bupivacaine during epidural anesthesia in children with Duchenne muscular dystrophy.

1 reference

12 December 2020

Anaesthetic management of the child with myotonic dystrophy: epidural anaesthesia as an alternative to general anaesthesia.

1 reference

12 December 2020

Simulation of an epidural test dose with intravenous isoproterenol in sevoflurane- and halothane-anesthetized children.

1 reference

12 December 2020

Pediatric regional anesthesia: beyond the caudal

1 reference

12 December 2020

Convulsions Associated With Pediatric Regional Anesthesia

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12 December 2020

Pharmacokinetics of ropivacaine following caudal analgesia in children.

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12 December 2020

Toxicity of lidocaine in adult, newborn, and fetal sheep.

1 reference

12 December 2020

Comparison of the fascia iliaca compartment block with the 3-in-1 block in children

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12 December 2020

Pharmacokinetics and metabolism of the anilide local anaesthetics in neonates. 11 Etidocaine

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12 December 2020

Serum concentrations of bupivacaine during prolonged continuous paravertebral infusion in young infants

1 reference

12 December 2020

Post-tonsillectomy infiltration with bupivacaine reduces immediate postoperative pain in children

1 reference

12 December 2020

The plasma concentration of lidocaine's principal metabolite increases during continuous epidural anesthesia in infants and children.

1 reference

12 December 2020

Evaluating T-wave amplitude as a guide for detecting intravascular injection of a test dose in anesthetized children.

1 reference

12 December 2020

The comparative toxicity of ropivacaine and bupivacaine at equipotent doses in rats.

1 reference

12 December 2020

Methemoglobinemia associated with a prilocaine-lidocaine cream.

1 reference

12 December 2020

1,000 consecutive blocks in a children's hospital: How to manage them safely.

1 reference

12 December 2020

Plasma bupivacaine concentrations during caudal analgesia and ilioinguinal-iliohypogastric nerve block in children.

1 reference

12 December 2020

Ropivacaine pharmacokinetics after caudal block in 1-8 year old children

1 reference

12 December 2020

Myocardial and cerebral drug concentrations and the mechanisms of death after fatal intravenous doses of lidocaine, bupivacaine, and ropivacaine in the sheep.

1 reference

12 December 2020

Perioperative changes in alpha 1-acid glycoprotein concentrations in infants undergoing major surgery

1 reference

12 December 2020

Improved outcome utilizing spinal anesthesia in high-risk infants

1 reference

12 December 2020

Bupivacaine in children: pharmacokinetics following caudal anesthesia.

1 reference

12 December 2020

Recovery after paediatric daycase herniotomy performed under spinal anaesthesia.

1 reference

12 December 2020

Transient neurologic symptom (TNS) following intrathecal ropivacaine.

1 reference

12 December 2020

Bupivacaine 0.125% produces motor block and weakness with fentanyl epidural analgesia in children.

1 reference

12 December 2020

Plasma bupivacaine concentrations in children during caudal epidural analgesia.

1 reference

12 December 2020

Continuous caudal anesthesia for inguinal hernia repair in former preterm infants.

1 reference

12 December 2020

Lumbar plexus block in children: a comparison of two procedures in 50 patients

1 reference

12 December 2020

Dilution of spinal lidocaine does not alter the incidence of transient neurologic symptoms

1 reference

12 December 2020

1 reference

12 December 2020

Pediatric regional anesthesia.

1 reference

12 December 2020

Duration of spinal anesthesia in infants less than one year of age. Comparison of three hyperbaric techniques.

1 reference

12 December 2020

Simulation of an epidural test dose with intravenous epinephrine in sevoflurane-anesthetized children.

1 reference

12 December 2020

Brachial plexus anesthesia in pediatric patients.

1 reference

12 December 2020

Caudal anesthesia for neonatal anoperineal and rectal operations

1 reference

12 December 2020

Systemic toxicity and resuscitation in bupivacaine-, levobupivacaine-, or ropivacaine-infused rats

1 reference

12 December 2020

Influence of midazolam on the plasma concentrations of mepivacaine after lumbar epidural injection in children.

1 reference

12 December 2020

The effective use of intrapleural bupivacaine for analgesia after thoracic and subcostal incisions in children.

1 reference

12 December 2020

Continuous epidural butorphanol relieves pruritus associated with epidural morphine infusions in children.

1 reference

12 December 2020

Infants tolerate spinal anesthesia with minimal overall autonomic changes: analysis of heart rate variability in former premature infants undergoing hernia repair.

1 reference

12 December 2020

The neurotoxicity of drugs given intrathecally (spinal)

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12 December 2020

Acute toxicity of ropivacaine compared with that of bupivacaine.

1 reference

12 December 2020

The pharmacokinetics of epidural ropivacaine in infants and young children

1 reference

12 December 2020

The influence of age on the cardiovascular toxicity of intravenous bupivacaine in young dogs

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12 December 2020

Pediatric neuraxial blockade

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12 December 2020

Bupivacaine for caudal analgesia in infants and children: the optimal effective concentration.

1 reference

12 December 2020

Continuous regional anaesthesia in infants.

1 reference

12 December 2020

Inadvertent administration of intravenous ropivacaine in a child

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12 December 2020

Caudal and epidural anaesthesia with ropivacaine in children

1 reference

12 December 2020

Arterial and venous plasma levels of bupivacaine following peripheral nerve blocks

1 reference

12 December 2020

Seizures secondary to oral viscous lidocaine

1 reference

12 December 2020

Intravenous regional anesthesia in the treatment of forearm and wrist fractures and dislocations in children.

1 reference

12 December 2020

A comparison of the cardiovascular effects of levobupivacaine and rac-bupivacaine following intravenous administration to healthy volunteers

1 reference

12 December 2020

A comparison of the electrocardiographic cardiotoxic effects of racemic bupivacaine, levobupivacaine, and ropivacaine in anesthetized swine.

1 reference

12 December 2020

Plasma bupivacaine concentrations following ilioinguinal-iliohypogastric nerve blockade in children.

1 reference

12 December 2020

Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.

1 reference

12 December 2020

Inverse relationship between age-dependent erythrocyte activity of methaemoglobin reductase and prilocaine-induced methaemoglobinaemia during infancy.

1 reference

12 December 2020

Caudal block with 4 mg x kg-1 (1.6 ml x kg-1) of bupivacaine 0.25% in children undergoing surgical correction of congenital pyloric stenosis

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12 December 2020

Lumbar epidural anesthesia for operative and postoperative pain relief in infants and young children

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12 December 2020

Local anesthetics for the pediatric patient

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12 December 2020

Femoral and lateral femoral cutaneous nerve block for muscle biopsies in children

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12 December 2020

Trans-sacral extradural anesthesia in pediatrics

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12 December 2020

Cardiovascular and central nervous system effects of intravenous levobupivacaine and bupivacaine in sheep.

1 reference

12 December 2020

Comparison of ring block, dorsal penile nerve block, and topical anesthesia for neonatal circumcision: a randomized controlled trial.

1 reference

12 December 2020

Mini-dose Bier block intravenous regional anesthesia in the emergency department treatment of pediatric upper-extremity injuries.

1 reference

12 December 2020

Accidental intravenous levobupivacaine

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12 December 2020

Epidural analgesia for major neonatal surgery

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12 December 2020

Lessons from 1100 pediatric caudal blocks in a teaching hospital

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12 December 2020

Ventricular tachycardia and brief cardiovascular collapse in two infants after caudal anesthesia using a bupivacaine-epinephrine solution

1 reference

12 December 2020

Outpatient treatment of upper extremity injuries in childhood using intravenous regional anaesthesia

1 reference

12 December 2020

Cardiovascular criteria for epidural test dosing in sevoflurane- and halothane-anesthetized children.

1 reference

12 December 2020

Caudal anaesthesia in children and spread of 1 per cent lignocaine. A statistical study.

1 reference

12 December 2020

Plasma concentrations of bupivacaine after combined spinal epidural anaesthesia in infants and neonates.

1 reference

12 December 2020

Methaemoglobinaemia in children treated with prilocaine-lignocaine cream

1 reference

12 December 2020

Efficacy of adrenaline, lignocaine-adrenaline and isoprenaline as a test dose in halothane-anaesthetized lambs.

1 reference

12 December 2020

Free and total bupivacaine plasma concentrations after continuous epidural anaesthesia in infants and children.

1 reference

12 December 2020

Left ventricular functions are not impaired after lumbar epidural anaesthesia in young children.

1 reference

12 December 2020

Use of continuous retropleural bupivacaine in postoperative pain management for pediatric thoracotomy

1 reference

12 December 2020

Complications of continuous epidural infusions for postoperative analgesia in children

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12 December 2020

The dose-response of caudal ropivacaine in children.

1 reference

12 December 2020

Regional anaesthesia in paediatric surgery.

1 reference

12 December 2020

Complications during spinal anesthesia in infants: high spinal blockade.

1 reference

12 December 2020

Levobupivacaine for ilioinguinal/iliohypogastric nerve block in children.

1 reference

12 December 2020

Effective pain relief with continuous intrapleural bupivacaine after thoracotomy in infants and children

1 reference

12 December 2020

Local anaesthetic effect of topical amethocaine gel in neonates: randomised controlled trial

1 reference

12 December 2020

Safety of lidocaine-prilocaine cream in the treatment of preterm neonates.

1 reference

12 December 2020

Evaluating hemodynamic and T wave criteria of simulated intravascular test doses using bupivacaine or isoproterenol in anesthetized children.

1 reference

12 December 2020

1995 Gaston Labat Lecture. Ropivacaine. White knight or dark horse?

1 reference

12 December 2020

Effects of age on the serum concentration of alpha 1-acid glycoprotein and the binding of lidocaine in pediatric patients.

1 reference

12 December 2020

Intravenous regional anesthesia: a safe and cost-effective outpatient anesthetic for upper extremity fracture treatment in children.

1 reference

12 December 2020

Rapid onset of seizures following aspiration of viscous lidocaine

1 reference

12 December 2020

Caudal analgesia in children. Five hundred cases for procedures below the diaphragm.

1 reference

12 December 2020

Electrocardiographic and hemodynamic changes associated with unintentional intravascular injection of bupivacaine with epinephrine in infants.

1 reference

12 December 2020

The lumbosacral epidural block: a modified Taylor approach for abdominal urologic surgery in children.

1 reference

12 December 2020

Neurologic complications of spinal and epidural anesthesia

1 reference

12 December 2020

Spinal anaesthesia for inguinal hernia repair in high-risk neonates.

1 reference

12 December 2020

The influence of midazolam on the plasma concentrations of bupivacaine and lidocaine after caudal injection of a mixture of the local anesthetics in children

1 reference

12 December 2020

Lumbar and thoracic epidural anesthesia for urologic and upper abdominal surgery in infants and children.

1 reference

12 December 2020

Prilocaine-induced methemoglobinemia in a newborn infant.

1 reference

12 December 2020

The pharmacokinetics of bupivacaine following interpleural nerve block in infants of very low birthweight.

1 reference

12 December 2020

Single-dose caudal anesthesia for major intraabdominal operations in high-risk infants.

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12 December 2020

Clearance and metabolism of mepivacaine in the human neonate.

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12 December 2020

Plasma bupivacaine concentrations after axillary block in children.

1 reference

12 December 2020

Bupivacaine for intercostal nerve blocks in children: blood concentrations and pharmacokinetics

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12 December 2020

Plasma concentrations of bupivacaine in neonates after continuous epidural infusion.

1 reference

12 December 2020

Intravenous isoproterenol as a marker for epidural test-dosing in children.

1 reference

12 December 2020

Recurrent seizures following mucosal application of TAC.

1 reference

12 December 2020

[Use of EMLA cream in premature and full-term newborn infants. Study of efficacy and tolerance]

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12 December 2020

Continuous epidural infusion of bupivacaine for postoperative pain relief in children.

1 reference

12 December 2020

Caudal block in children: ropivacaine compared with bupivacaine

1 reference

12 December 2020

Pharmacokinetics of 0.2% ropivacaine and 0.2% bupivacaine following caudal blocks in children.

1 reference

12 December 2020

Transient neurologic symptoms after spinal anesthesia: an epidemiologic study of 1,863 patients

1 reference

12 December 2020

The pharmacokinetics of caudal ropivacaine 0.2% in children. A study of infants aged less than 1 year and toddlers aged 1-5 years undergoing inguinal hernia repair.

1 reference

12 December 2020

Chloroprocaine for epidural anesthesia in infants and children.

1 reference

12 December 2020

Pharmacokinetics of bupivacaine during postoperative epidural infusion: enantioselectivity and role of protein binding

1 reference

12 December 2020

Pharmacokinetics and analgesic effect of ropivacaine following ilioinguinal/iliohypogastric nerve block in children

1 reference

12 December 2020

Ropivacaine 0.25% compared with bupivacaine 0.25% by the caudal route.

1 reference

12 December 2020

Transient neurologic symptoms after epidural analgesia in a five-year-old child

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12 December 2020

Toxicity of local anesthetics in infants and children

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12 December 2020

Sciatic nerve blocks in children: comparison of the posterior, anterior, and lateral approaches in 180 pediatric patients.

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12 December 2020

Optimum concentration of bupivacaine for combined caudal--general anesthesia in children

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12 December 2020

Continuous Infusion of Bupivacaine Via Intrapleural Catheter for Analgesia after Thoracotomy in Children

1 reference

12 December 2020

Simulation of an epidural test dose with intravenous isoproterenol in awake and in halothane-anesthetized children

1 reference

12 December 2020

Pharmacokinetics of bupivacaine following intraoperative intercostal nerve block in neonates and in infants aged less than 6 months.

1 reference

12 December 2020

Ropivacaine vs bupivacaine in major surgery in infants.

1 reference

12 December 2020

Caudal anesthesia in pediatric surgery: success rate and adverse effects in 750 consecutive patients.

1 reference

12 December 2020

Stereospecific effect of bupivacaine isomers on atrioventricular conduction in the isolated perfused guinea pig heart.

1 reference

12 December 2020

Lumbar epidural anaesthesia for inguinal hernia repair in low birth weight infants

1 reference

12 December 2020

Developmental neurophysiology of mammalian peripheral nerves and age-related differential sensitivity to local anaesthetic.

1 reference

12 December 2020

Epidural anaesthesia through caudal catheters for inguinal herniotomies in awake ex-premature babies.

1 reference

12 December 2020

Bupivacaine-induced cardiac toxicity in neonates: successful treatment with intravenous phenytoin.

1 reference

12 December 2020

Spinal anesthesia reduces the hazard of apnea in high-risk infants.

1 reference

12 December 2020

Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine.

1 reference

12 December 2020

Smaller children have greater bupivacaine plasma concentrations after ilioinguinal block.

1 reference

12 December 2020

Caudal anesthesia in the awake, high-risk infant.

1 reference

12 December 2020

Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics.

1 reference

12 December 2020

Spinal anesthesia for gastrostomy in an infant with nemaline myopathy.

1 reference

12 December 2020

Local anaesthetic agents in infancy

1 reference

12 December 2020

Circumcision supplemented by dorsal penile nerve block with 0.75% ropivacaine: a complication.

1 reference

12 December 2020

Dosage of lidocaine for caudal anesthesia in infants and children

1 reference

12 December 2020

Plasma cholinesterase activity in newborns and infants.

1 reference

12 December 2020

Spinal anesthesia in premature infants recovering from respiratory distress syndrome.

1 reference

12 December 2020

Methaemoglobin formation after the use of EMLA cream in term neonates.

1 reference

12 December 2020

Lidocaine plasma concentrations in pediatric patients after providing airway topical anesthesia from a calibrated device.

1 reference

12 December 2020

Prolonged seizures associated with the use of viscous lidocaine

1 reference

12 December 2020

Continuous epidural anesthesia in children under 1 year of age

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12 December 2020

Intravenous lidocaine overdosage in a child.

1 reference

12 December 2020

Combined spinal and epidural anaesthesia for major abdominal surgery in infants.

1 reference

12 December 2020

Oral clonidine premedication does not change efficacy of simulated epidural test dose in sevoflurane-anesthetized children

1 reference

12 December 2020

Adverse effects of regional anaesthesia in children.

1 reference

12 December 2020

Epidural and subarachnoid blockade in children.

1 reference

12 December 2020

Efficacy of simulated epinephrine-containing epidural test dose after intravenous atropine during isoflurane anesthesia in children.

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12 December 2020

Spinal anaesthesia in infants and children

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12 December 2020

Local anesthetics in the management of acute pain in children

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12 December 2020

Blood concentrations of lidocaine, mepivacaine and bupivacaine during caudal analgesia in children.

1 reference

12 December 2020

Ropivacaine in paediatric surgery: preliminary results.

1 reference

12 December 2020

Eutectic mixture of local anesthetics (EMLA): what is it? What does it do?

1 reference

12 December 2020

Caudal ropivacaine in infants: population pharmacokinetics and plasma concentrations

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12 December 2020

Pharmacokinetics of bupivacaine following caudal anesthesia in infants.

1 reference

12 December 2020

Toxicity--seizures in an infant caused by (or related to) oral viscous lidocaine use

1 reference

12 December 2020

Toxicity of local anesthetics in the fetus and the newborn

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12 December 2020

The minimum local anesthetic concentration of ropivacaine for caudal analgesia in children

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12 December 2020

Ropivacaine: is it time for children?

1 reference

12 December 2020

Pharmacokinetics of the enantiomers of bupivacaine and mepivacaine after epidural administration of the racemates.

1 reference

12 December 2020

Comparison of ropivacaine 0.1% and 0.2% with bupivacaine 0.2% for single-shot caudal anaesthesia in children

1 reference

12 December 2020

Plasma concentrations of prilocaine and lidocaine and methaemoglobin formation in infants after epicutaneous application of a 5% lidocaine-prilocaine (EMLA).

1 reference

12 December 2020

Epidemiology and morbidity of regional anesthesia in children: a one-year prospective survey of the French-Language Society of Pediatric Anesthesiologists.

1 reference

12 December 2020

Continuous paravertebral block for postthoracotomy analgesia in children

1 reference

12 December 2020

Spinal anaesthesia in newborns: total and free bupivacaine plasma concentration.

1 reference

12 December 2020

Adequacy of caudal analgesia in children after penoscrotal and inguinal surgery using 0.5 or 1.0 ml.kg-1 bupivacaine 0.125%.

1 reference

12 December 2020

Caudal epidural anesthesia in conscious premature and high-risk infants.

1 reference

12 December 2020

A grand mal convulsion in a child in association with a continuous epidural infusion of bupivacaine

1 reference

12 December 2020

A comparison of epidural levobupivacaine 0.75% with racemic bupivacaine for lower abdominal surgery

1 reference

12 December 2020

Regional anesthesia in children: what have we learned?

1 reference

12 December 2020

Plasma bupivacaine concentrations associated with continuous extradural infusions in babies.

1 reference

12 December 2020

Pharmacokinetics of lignocaine in children following caudal anaesthesia.

1 reference

12 December 2020

Bupivacaine toxicity secondary to continuous caudal epidural infusion in children

1 reference

12 December 2020

Local anaesthetic techniques in paediatric surgery

1 reference

12 December 2020

Spinal anaesthesia for paediatric day-case surgery: a double-blind, randomized, parallel group, prospective comparison of isobaric and hyperbaric bupivacaine.

1 reference

12 December 2020

Seizures Occurring in Pediatric Patients Receiving Continuous Infusion of Bupivacaine

1 reference

12 December 2020

Neurologic evaluation of infant and adult rats before and after sciatic nerve blockade.

1 reference

12 December 2020

Regional anesthesia in children

1 reference

12 December 2020

Successful resuscitation following massive bupivacaine overdose.

1 reference

12 December 2020

A risk-benefit assessment of topical percutaneous local anaesthetics in children

1 reference

12 December 2020

Evaluation of caudal anaesthesia performed in conscious ex-premature infants for inguinal herniotomies

1 reference

12 December 2020

Blockade of the sciatic nerve in the popliteal fossa: a system for standardization in children.

1 reference

12 December 2020

Effects of caudal block with mepivacaine on resting ventilation and ventilatory response to carbon dioxide in sedated children.

1 reference

12 December 2020

Lidocaine pharmacokinetics in children during general anesthesia.

1 reference

12 December 2020

Spinal anesthesia for surgery in the high-risk infant.

1 reference

12 December 2020

Bupivacaine plasma concentrations during continuous epidural anesthesia in infants and children.

1 reference

12 December 2020

10.2165/00128072-200204100-00003

Identifiers

DOI

1 reference

PubMed ID

12269841

Dimensions Publication ID

5 August 2017

0 references

1 reference

PubMed ID

12269841