(Q34891145)

5 August 2017

title

Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2 (English)

1 reference

5 August 2017

1 reference

James W Antoon

1

1 reference

5 August 2017

Martin D White

2

1 reference

5 August 2017

Evelyn M Slaughter

3

1 reference

5 August 2017

Jennifer L Driver

4

1 reference

5 August 2017

Hafez S Khalili

5

1 reference

5 August 2017

Steven Elliott

6

1 reference

5 August 2017

Charles D Smith

7

1 reference

5 August 2017

Matthew E Burow

8

1 reference

5 August 2017

Barbara S Beckman

9

1 reference

5 August 2017

publication date

1 April 2011

1 reference

Cancer Biology and Therapy

5 August 2017

published in

1 reference

5 August 2017

volume

11

1 reference

5 August 2017

issue

7

1 reference

5 August 2017

page(s)

678-689

1 reference

Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

A novel sphingosine kinase inhibitor induces autophagy in tumor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Novel D: -erythro N-octanoyl sphingosine analogs as chemo- and endocrine-resistant breast cancer therapeutics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Sphingolipids as determinants of apoptosis and chemoresistance in the MCF-7 cell model system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Identification of the potent phytoestrogen glycinol in elicited soybean (Glycine max).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Role for sphingosine kinase 1 in colon carcinogenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Roles of bioactive sphingolipids in cancer biology and therapeutics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Gene expression profiling of breast cancer cells in response to gemcitabine: NF-kappaB pathway activation as a potential mechanism of resistance.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

The NF-kappaB/IkappaB signaling system: a molecular target in breast cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Discovery and evaluation of inhibitors of human sphingosine kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

NF-kappaB and breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Apoptosis, p53, and tumor cell sensitivity to anticancer agents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084971

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCBT.11.7.14903

Novel ceramide analogs as potential chemotherapeutic agents in breast cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCBT.11.7.14903

NF-kappa B-mediated chemoresistance in breast cancer cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCBT.11.7.14903

Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21307639

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CBT.11.7.14903

1 reference

release_tl5mh3lnfndkhagdqh6zsnrx7i

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tl5mh3lnfndkhagdqh6zsnrx7i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3084971

1 reference

5 August 2017

1 reference