(Q34906959)

5 August 2017

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title

Novel strategies for targeting the dimerization interface of HIV protease with cross-linked interfacial peptides (English)

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5 August 2017

Michael J Bowman

1

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5 August 2017

Jean Chmielewski

series ordinal

2

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5 August 2017

publication date

1 January 2002

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5 August 2017

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5 August 2017

volume

66

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5 August 2017

issue

2

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5 August 2017

page(s)

126-133

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

5 August 2017

cites work

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Active human immunodeficiency virus protease is required for viral infectivity

21 January 2018

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Trans-dominant inhibitory human immunodeficiency virus type 1 protease monomers prevent protease activation and virion maturation

21 January 2018

1 reference

Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design

21 January 2018

1 reference

Approaches to the design of effective HIV-1 protease inhibitors

21 January 2018

1 reference

Inhibitors of HIV-1 protease: a major success of structure-assisted drug design

21 January 2018

1 reference

HIV-1 protease inhibitors. A review for clinicians

21 January 2018

1 reference

A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

21 January 2018

1 reference

Indinavir-associated lipodystrophy.

21 January 2018

1 reference

Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance

21 January 2018

1 reference

Inhibiting the assembly of protein-protein interfaces.

21 January 2018

1 reference

Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

21 January 2018

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Identification of a clinical isolate of HIV-1 with an isoleucine at position 82 of the protease which retains susceptibility to protease inhibitors

21 January 2018

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Dissociation and association of the HIV-1 protease dimer subunits: equilibria and rates.

21 January 2018

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Comparison of inhibitor binding in HIV-1 protease and in non-viral aspartic proteases: the role of the flap

21 January 2018

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Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases

21 January 2018

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Inhibition of HIV-1 protease by short peptides derived from the terminal segments of the protease

21 January 2018

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Lipopeptides as dimerization inhibitors of HIV-1 protease

21 January 2018

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Design, synthesis, and evaluation of conformationally constrained tongs, new inhibitors of HIV-1 protease dimerization

21 January 2018

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Design and synthesis of new inhibitors of HIV-1 protease dimerization with conformationally constrained templates

21 January 2018

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Small-Molecule Inhibitors of HIV-1 Protease Dimerization Derived from Cross-Linked Interfacial Peptides This work was supported by NIH (GM52739) and NSF (9457372-CHE).

21 January 2018

1 reference

A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo

21 January 2018

1 reference

Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface

21 January 2018

1 reference

Inhibiting the dimeric restriction endonuclease EcoRI using interfacial helical peptides

21 January 2018

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Synthetic interface peptides as inactivators of multimeric enzymes: inhibitory and conformational properties of three fragments from Lactobacillus casei thymidylate synthase

21 January 2018

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Selective disruption of protein aggregation by cyclodextrin dimers

21 January 2018

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Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

21 January 2018

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Synthetic peptides as inactivators of multimeric enzymes: inhibition of Plasmodium falciparum triosephosphate isomerase by interface peptides

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIP.10232

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5 August 2017

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