(Q34907871)

English

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals

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Europe PubMed Central

PubMed publication ID

5 August 2017

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1-deoxymethylsphinganine(1+)

1 reference

ChEBI release 2020-05-28

1-deoxysphinganine(1+)

1 reference

ChEBI release 2020-05-28

1 reference

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author name string

Nicholas C Zitomer

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Trevor Mitchell

2

1 reference

Europe PubMed Central

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5 August 2017

Kenneth A Voss

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Genevieve S Bondy

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Sarah T Pruett

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ethel C Garnier-Amblard

6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Lanny S Liebeskind

7

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Hyejung Park

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Elaine Wang

9

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

M Cameron Sullards

10

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Alfred H Merrill

11

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ronald T Riley

12

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Europe PubMed Central

PubMed publication ID

5 August 2017

language of work or name

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publication date

18 December 2008

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Europe PubMed Central

PubMed publication ID

5 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

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5 August 2017

284

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Europe PubMed Central

PubMed publication ID

5 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

4786-4795

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Kinetics and metabolic specificities of Vero cells in bioreactor cultures with serum-free medium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Sphingosine-1-phosphate lyase in development and disease: sphingolipid metabolism takes flight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCzeta activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

A concise and scalable synthesis of high enantiopurity (-)-D-erythro-sphingosine using peptidyl thiol ester-boronic acid cross-coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Steroidogenic factor-1 is a sphingolipid binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Differential sensitivity of rat kidney and liver to fumonisin toxicity: organ-specific differences in toxin accumulation and sphingoid base metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Discovery and occurrence of the fumonisins: a historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Fumonisin B1 dosimetry in relation to cancer initiation in rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Fumonisin inhibition of de novo sphingolipid biosynthesis and cytotoxicity are correlated in LLC-PK1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643501

8 July 2018

Tissue sphinganine as a biomarker of fumonisin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808798200

21 January 2018

Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808798200

21 January 2018

Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808798200

21 January 2018

Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808798200

21 January 2018

A single extraction method for the analysis by liquid chromatography/tandem mass spectrometry of fumonisins and biomarkers of disrupted sphingolipid metabolism in tissues of maize seedlings.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808798200

21 January 2018

Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808798200

21 January 2018

Alteration in sphingolipid metabolism: bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices

1 reference

https://pubmed.ncbi.nlm.nih.gov/19095642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19095642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fermentation, partial purification, and use of serine palmitoyltransferase inhibitors from Isaria (= Cordyceps) sinclairii

1 reference

https://pubmed.ncbi.nlm.nih.gov/19095642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine palmitoyltransferase inhibition reverses anti-proliferative effects of ceramide synthase inhibition in cultured renal cells and suppresses free sphingoid base accumulation in kidney of BALBc mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19095642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19095642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M808798200

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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