(Q34919524)

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The hexosamine biosynthesis inhibitor azaserine prevents endothelial inflammation and dysfunction under hyperglycemic condition through antioxidant effects

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

The hexosamine biosynthesis inhibitor azaserine prevents endothelial inflammation and dysfunction under hyperglycemic condition through antioxidant effects (English)

1 reference

Europe PubMed Central

5 August 2017

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1 reference

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ChEBI release 2020-05-28

author name string

Angana Gupta Rajapakse

1

1 reference

Europe PubMed Central

5 August 2017

Xiu-Fen Ming

2

1 reference

Europe PubMed Central

5 August 2017

João M Carvas

3

1 reference

Europe PubMed Central

5 August 2017

Zhihong Yang

4

1 reference

Europe PubMed Central

5 August 2017

publication date

9 January 2009

1 reference

Europe PubMed Central

5 August 2017

American Journal of Physiology Heart and Circulatory Physiology

1 reference

Europe PubMed Central

5 August 2017

296

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Europe PubMed Central

5 August 2017

3

1 reference

Europe PubMed Central

5 August 2017

H815-22

1 reference

Europe PubMed Central

5 August 2017

Hyperglycemia and the O-GlcNAc transferase in rat aortic smooth muscle cells: elevated expression and altered patterns of O-GlcNAcylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

The pathobiology of diabetic complications: a unifying mechanism

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Biochemistry and molecular cell biology of diabetic complications

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Hexosamines, insulin resistance, and the complications of diabetes: current status

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Vascular adhesion molecules in atherosclerosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

The mechanisms of inhibitory actions of gliclazide on neutrophils-endothelial cells adhesion and surface expression of endothelial adhesion molecules mediated by a high glucose concentration

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

The relationship between plasma asymmetrical dimethyl-L-arginine and inflammation and adhesion molecule levels in subjects with normal, impaired, and diabetic glucose tolerance

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

The hexosamine signaling pathway: deciphering the "O-GlcNAc code"

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Resveratrol blocks high glucose-induced mitochondrial reactive oxygen species production in bovine aortic endothelial cells: role of phase 2 enzyme induction?

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Intermittent high glucose enhances ICAM-1, VCAM-1 and E-selectin expression in human umbilical vein endothelial cells in culture: the distinct role of protein kinase C and mitochondrial superoxide production

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: direct measurements and formation of hydrogen peroxide and peroxynitrite

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Synergistic relationship between hyperglycaemia and inflammation with respect to clinical outcomes in non-ST-elevation acute coronary syndromes: analyses from OPUS-TIMI 16 and TACTICS-TIMI 18.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Expression of bovine and mouse endothelial cell antioxidant enzymes following TNF-alpha exposure

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti-oxidant alpha-lipoic acid.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Hyperglycemia potentiates the proatherogenic effects of C-reactive protein: reversal with rosiglitazone.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00756.2008

21 January 2018

Identifiers

10.1152/AJPHEART.00756.2008

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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