(Q34926575)

5 August 2017

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title

On the road to reading the RNA-interference code (English)

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5 August 2017

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Haruhiko Siomi

1

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5 August 2017

Mikiko C Siomi

series ordinal

2

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5 August 2017

language of work or name

English

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publication date

1 January 2009

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5 August 2017

number of pages

9

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inferred from page(s)

published in

Nature

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5 August 2017

volume

457

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5 August 2017

issue

7228

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5 August 2017

page(s)

396-404

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The impact of next-generation sequencing technology on genetics

5 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE07754

Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes

21 January 2018

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12 December 2020

P bodies: at the crossroads of post-transcriptional pathways

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12 December 2020

An endogenous small interfering RNA pathway in Drosophila

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12 December 2020

A mammalian microRNA expression atlas based on small RNA library sequencing

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12 December 2020

Selective blockade of microRNA processing by Lin28

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12 December 2020

Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila

1 reference

12 December 2020

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

1 reference

12 December 2020

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

1 reference

12 December 2020

Conserved ribonuclease, Eri1, negatively regulates heterochromatin assembly in fission yeast

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12 December 2020

Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

1 reference

12 December 2020

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

1 reference

12 December 2020

The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila

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12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

12 December 2020

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

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12 December 2020

SMAD proteins control DROSHA-mediated microRNA maturation

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12 December 2020

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

1 reference

12 December 2020

Molecular basis for target RNA recognition and cleavage by human RISC.

1 reference

12 December 2020

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

1 reference

12 December 2020

Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells

1 reference

12 December 2020

A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila

1 reference

12 December 2020

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

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12 December 2020

Principles of microRNA-target recognition

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12 December 2020

RETRACTED: Secondary siRNAs result from unprimed RNA synthesis and form a distinct class

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12 December 2020

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

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12 December 2020

MicroRNA biogenesis: coordinated cropping and dicing

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12 December 2020

Small non-coding RNAs in animal development

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12 December 2020

Mechanisms of gene silencing by double-stranded RNA

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12 December 2020

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

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12 December 2020

An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster.

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12 December 2020

Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation

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12 December 2020

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

1 reference

12 December 2020

Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation

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12 December 2020

Perspective: machines for RNAi

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12 December 2020

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

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12 December 2020

Messenger-RNA-binding proteins and the messages they carry

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12 December 2020

Crystal structure of Argonaute and its implications for RISC slicer activity

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12 December 2020

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

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12 December 2020

Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends

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12 December 2020

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

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12 December 2020

Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway.

1 reference

12 December 2020

Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline

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12 December 2020

RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing

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12 December 2020

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

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12 December 2020

Target mimicry provides a new mechanism for regulation of microRNA activity

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12 December 2020

MicroRNAs and the advent of vertebrate morphological complexity

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12 December 2020

Distinct populations of primary and secondary effectors during RNAi in C. elegans

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12 December 2020

Conserved themes in small-RNA-mediated transposon control

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12 December 2020

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi

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12 December 2020

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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12 December 2020

Structure of the guide-strand-containing argonaute silencing complex

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12 December 2020

RNA helicase A interacts with RISC in human cells and functions in RISC loading

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12 December 2020

The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs

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12 December 2020

PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans

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12 December 2020

Kinetic analysis of the RNAi enzyme complex

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12 December 2020

A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase

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12 December 2020

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

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12 December 2020

Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans

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12 December 2020

Small RNAs in viral infection and host defense

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12 December 2020

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

1 reference

12 December 2020

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

1 reference

12 December 2020

The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members

1 reference

12 December 2020

Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

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12 December 2020

A distinct small RNA pathway silences selfish genetic elements in the germline

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12 December 2020

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

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12 December 2020

Common logic of transcription factor and microRNA action

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12 December 2020

Asymmetry in the assembly of the RNAi enzyme complex

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12 December 2020

3' end mRNA processing: molecular mechanisms and implications for health and disease

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12 December 2020

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

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12 December 2020

A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.

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12 December 2020

A novel class of small RNAs bind to MILI protein in mouse testes

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12 December 2020

The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC.

1 reference

12 December 2020

Developmentally regulated piRNA clusters implicate MILI in transposon control

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12 December 2020

Functional siRNAs and miRNAs Exhibit Strand Bias

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12 December 2020

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

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12 December 2020

Intronic microRNA precursors that bypass Drosha processing

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12 December 2020

In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans

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12 December 2020

Characterization of the piRNA Complex from Rat Testes

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12 December 2020

Single processing center models for human Dicer and bacterial RNase III

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12 December 2020

Argonaute proteins: key players in RNA silencing

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12 December 2020

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

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12 December 2020

Structural determinants of RNA recognition and cleavage by Dicer

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12 December 2020

Sorting of Drosophila small silencing RNAs

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12 December 2020

The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

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12 December 2020

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

1 reference

12 December 2020

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

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12 December 2020

Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide

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12 December 2020

Specialization and evolution of endogenous small RNA pathways

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12 December 2020

Processing of primary microRNAs by the Microprocessor complex

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12 December 2020

The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated

1 reference

12 December 2020

Argonaute2 is the catalytic engine of mammalian RNAi

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12 December 2020

Slicer function of Drosophila Argonautes and its involvement in RISC formation

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12 December 2020

Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome

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12 December 2020

The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs

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12 December 2020

A protein sensor for siRNA asymmetry

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12 December 2020

The Microprocessor complex mediates the genesis of microRNAs

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12 December 2020

A germline-specific class of small RNAs binds mammalian Piwi proteins

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12 December 2020

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

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12 December 2020

Antiviral immunity directed by small RNAs

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12 December 2020

Argonautes confront new small RNAs

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12 December 2020

Identifiers

DOI

10.1038/NATURE07754

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Dimensions Publication ID

5 August 2017

1040500341

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