(Q34926648)

5 August 2017

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title

Retinoic acid resistance in acute promyelocytic leukemia (English)

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5 August 2017

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1 reference

Gallagher RE

1

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5 August 2017

1 October 2002

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5 August 2017

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5 August 2017

16

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5 August 2017

1940-1958

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5 August 2017

10

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402719

5 August 2017

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cites work

Acute promyelocytic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

The molecular biology of acute promyelocytic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

All-trans retinoic acid significantly increases 5-year survival in patients with acute promyelocytic leukemia: long-term follow-up of the New York study

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

All-trans-retinoic acid in acute promyelocytic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

All-trans retinoic acid followed by chemotherapy for salvage of refractory or relapsed acute promyelocytic leukemia.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Analysis of prognostic factors in newly diagnosed acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. Japan Adult Leukemia Study Group

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Treatment of newly-diagnosed acute promyelocytic leukemia with liposomal all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Treatment of newly diagnosed and relapsed acute promyelocytic leukemia with intravenous liposomal all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Advances in the treatment of relapsed acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Association of t(15;17) and t(8;21) in the initial phase of an acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Co-expression of two FAB-specific chromosome changes, t(15;17) and t(8;21), in a case of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Aml1/ETO and Pml/RARA rearrangements in a case of AML-M2 acute myeloblastic leukemia with t(15;17)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Simultaneous PML/RAR alpha and AML 1/ETO gene rearrangements in a patient with acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Simultaneous PML/RARalpha and AML1/ETO expression with t(15;17) at onset and relapse with only t(8;21) in an acute promyelocytic leukemia patient

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Pretreatment characteristics and clinical outcome of acute promyelocytic leukaemia patients according to the PML-RAR alpha isoforms: a study of the PETHEMA group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

In vitro all-trans retinoic acid sensitivity of acute promyelocytic leukemia blasts: a novel indicator of poor patient outcome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation. APL Study Group. Acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in v

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Regulation of retinoic acid metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Variability in the oral bioavailability of all-trans-retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Phase I evaluation of all-trans retinoic acid with and without ketoconazole in adults with solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Pharmacokinetics of all-trans-retinoic acid administered on an intermittent schedule.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Participation of P450 3A enzymes in rat hepatic microsomal retinoic acid 4-hydroxylation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Modulation of all-trans retinoic acid pharmacokinetics by liarozole

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Inhibition of all-trans-retinoic acid metabolism by fluconazole in vitro and in patients with acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoic acid biosynthesis and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

The cellular retinoic acid binding proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Topical glucocorticosteroids modulate the expression of CRABP I and II in human skin differently

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Localization of the RAR interaction domain of cellular retinoic acid binding protein-II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

The novel co-activator CRABPII binds to RARalpha and RXRalpha via two nuclear receptor interacting domains and does not require the AF-2 'core'.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Nuclear Detection of Cellular Retinoic Acid Binding Proteins I and II with New Antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoic acid synthesis and expression of cellular retinol-binding protein and cellular retinoic acid-binding protein type II are concurrent with decidualization of rat uterine stromal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

1 reference

7 January 2021

Clinical study of 9-cis retinoic acid (LGD1057) in acute promyelocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoic acid-induced differentiation of the human promyelocytic leukemia cell line, HL-60, and fresh human leukemia cells in primary culture: a model for differentiation inducing therapy of leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Two distinctly regulated events, priming and triggering, during retinoid-induced maturation and resistance of NB4 promyelocytic leukemia cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

All-trans retinoic acid pharmacokinetics and bioavailability in acute promyelocytic leukemia: intracellular concentrations and biologic response relationship.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Role of P-glycoprotein in all-trans retinoic acid (ATRA) resistance in acute promyelocytic leukaemia cells: analysis of intracellular concentration of ATRA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

All-trans retinoic acid (ATRA) differentiates acute promyelocytic leukemia cells independently of P-glycoprotein (P-gp) related multidrug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Variable regulation of sensitivity to retinoic acid-induced differentiation in wild-type and retinoic acid-resistant HL-60 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Low incidence of MDR1 expression in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

P-glycoprotein (PGP), lung resistance-related protein (LRP) and multidrug resistance-associated protein (MRP) expression in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Autoinduction of retinoic acid metabolism to polar derivatives with decreased biological activity in retinoic acid-sensitive, but not in retinoic acid-resistant human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Nucleocytoplasmic transport: Ran, beta and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Transport into and out of the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Molecular determinants of nuclear receptor-corepressor interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

The language of covalent histone modifications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Regulation of chromatin structure by site-specific histone H3 methyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

A transcriptional switch mediated by cofactor methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Increasing the complexity of coactivation in nuclear receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Chromatin remodeling machines: similar motors, ulterior motives

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Selectivity of chromatin-remodelling cofactors for ligand-activated transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoid X receptor (RXR) agonist-induced activation of dominant-negative RXR-retinoic acid receptor alpha403 heterodimers is developmentally regulated during myeloid differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

The cytokines IL-3 and GM-CSF regulate the transcriptional activity of retinoic acid receptors in different in vitro models of myeloid differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Orchestration of multiple arrays of signal cross-talk and combinatorial interactions for maturation and cell death: another vision of t(15;17) preleukemic blast and APL-cell maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Mutant AF-2 domain of PML-RARalpha in retinoic acid-resistant NB4 cells: differentiation induced by RA is triggered directly through PML-RARalpha and its down-regulation in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Identification of a receptor for the morphogen retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Role of the histone deacetylase complex in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

A unique carboxy-terminus truncation mutant of the retinoic acid receptor alpha gene associated with a variant marker chromosome in a retinoic acid resistant HL-60 subline

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Alterations of differentiation, clonal proliferation, cell cycle progression and bcl-2 expression in RAR alpha-altered sublines of HL-60.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Function of RARalpha during the maturation of neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Acute promyelocytic leukaemia cells resistant to retinoic acid show further perturbation of the RAR alpha signal transduction system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Novel mutation in the PML/RARalpha chimeric gene exhibits dramatically decreased ligand-binding activity and confers acquired resistance to retinoic acid in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Syndrome of resistance to thyroid hormone: insights into thyroid hormone action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Resistance to thyroid hormone (RTH) syndrome reveals novel determinants regulating interaction of T3 receptor with corepressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Androgen receptor signaling in androgen-refractory prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402719

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402719

1 reference

PubMed ID

12357346

Dimensions Publication ID

5 August 2017

0 references

1 reference

PubMed ID

12357346