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Statins as anti-inflammatory agents
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Statins as anti-inflammatory agents
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
main subject
inflammation
0 references
author name string
Gabriele Weitz-Schmidt
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
publication date
1 October 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
published in
Trends in Pharmacological Sciences
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
volume
23
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
page(s)
482-486
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
issue
10
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
cites work
Structural mechanism for statin inhibition of HMG-CoA reductase
1 reference
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Crossref
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Pharmacology of competitive inhibitors of HMG-CoA reductase.
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Protein prenylation: molecular mechanisms and functional consequences
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7 January 2021
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HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Stimulation of bone formation in vitro and in rodents by statins
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Crossref
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7 January 2021
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Statins as a newly recognized type of immunomodulator
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reference URL
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7 January 2021
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Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels. The Prospective Pravastatin Pooling project
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7 January 2021
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Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Statins do more than just lower cholesterol
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Disease-free intervals after partial ileal bypass in patients with coronary heart disease and hypercholesterolemia: report from the Program on the Surgical Control of the Hyperlipidemias (POSCH)
1 reference
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Crossref
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7 January 2021
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Statins for stroke: the second story?
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reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Effect of pravastatin on outcomes after cardiac transplantation.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Simvastatin reduces graft vessel disease and mortality after heart transplantation: a four-year randomized trial
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Crossref
reference URL
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7 January 2021
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Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events
1 reference
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Crossref
reference URL
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7 January 2021
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Cardiovascular disease. Does inflammation cut to the heart of the matter?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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inferred from DOI database lookup
Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemic rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Effects of pravastatin on chronic rejection of rat cardiac allografts.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Direct proinflammatory effect of C-reactive protein on human endothelial cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Inhibition of monocyte chemotactic protein-1 synthesis by statins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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HMG-CoA Reductase Inhibitors Decrease CD11b Expression and CD11b-Dependent Adhesion of Monocytes to Endothelium and Reduce Increased Adhesiveness of Monocytes Isolated From Patients With Hypercholesterolemia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Inhibitory effect of fluvastatin, an HMG-CoA reductase inhibitor, on the expression of adhesion molecules on human monocyte cell line
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Cerivastatin suppresses lipopolysaccharide-induced ICAM-1 expression through inhibition of Rho GTPase in BAEC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in pri
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Statins and monocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastatin in response to lipoproteins in human monocytes in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
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Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
retrieved
7 January 2021
based on heuristic
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Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
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Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Activators and target genes of Rel/NF-kappaB transcription factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
based on heuristic
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Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902077-1
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7 January 2021
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Identifiers
DOI
10.1016/S0165-6147(02)02077-1
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
PubMed ID
12368073
1 reference
stated in
Europe PubMed Central
PubMed ID
12368073
retrieved
5 August 2017
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