(Q34944459)

5 August 2017

1 reference

title

Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors (English)

1 reference

5 August 2017

Neelu Kaila

1

1 reference

5 August 2017

Bert E Thomas

series ordinal

2

1 reference

5 August 2017

publication date

1 November 2002

1 reference

Medicinal Research Reviews

5 August 2017

published in

1 reference

5 August 2017

volume

22

1 reference

5 August 2017

issue

6

1 reference

5 August 2017

page(s)

566-601

1 reference

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140.

5 August 2017

cites work

1 reference

Identification of an inducible endothelial-leukocyte adhesion molecule

21 January 2018

1 reference

A cell-surface molecule involved in organ-specific homing of lymphocytes

21 January 2018

1 reference

Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo

21 January 2018

1 reference

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

21 January 2018

1 reference

Mechanisms that regulate the function of the selectins and their ligands

21 January 2018

1 reference

PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus

21 January 2018

1 reference

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding

21 January 2018

1 reference

Tyrosine sulfation of P-selectin glycoprotein ligand-1 is required for high affinity binding to P-selectin

21 January 2018

1 reference

Sequential contribution of L- and P-selectin to leukocyte rolling in vivo

21 January 2018

1 reference

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

21 January 2018

1 reference

Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice

21 January 2018

1 reference

Selectinminus signCarbohydrate Interactions: From Natural Ligands to Designed Mimics

21 January 2018

1 reference

Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines.

21 January 2018

1 reference

Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1

21 January 2018

1 reference

Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion

21 January 2018

1 reference

The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding.

21 January 2018

1 reference

The complement binding-like domains of the murine homing receptor facilitate lectin activity

21 January 2018

1 reference

A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion

21 January 2018

1 reference

Structure of a C-type mannose-binding protein complexed with an oligosaccharide

21 January 2018

1 reference

Structure of a legume lectin with an ordered N-linked carbohydrate in complex with lactose

21 January 2018

1 reference

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

21 January 2018

1 reference

Structure of a selectin-like mutant of mannose-binding protein complexed with sialylated and sulfated Lewis(x) oligosaccharides

21 January 2018

1 reference

Structure-Activity Relationships of Sialyl Lewis x-Containing Oligosaccharides. 1. Effect of Modifications of the Fucose Moiety

21 January 2018

1 reference

Structure-function studies on selectin carbohydrate ligands. Modifications to fucose, sialic acid and sulphate as a sialic acid replacement

21 January 2018

1 reference

Synthesis of sialyl Lewis(x) mimics. Modifications of the 6-position of galactose

21 January 2018

1 reference

Structural requirements for the carbohydrate ligand of E-selectin

21 January 2018

1 reference

Studies on selectin blocker. 3. Investigation of the carbohydrate ligand sialyl Lewis X recognition site of P-selectin

21 January 2018

1 reference

Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders

21 January 2018

1 reference

Application of homonuclear 3D NMR experiments and 1D analogs to study the conformation of sialyl Lewis(x) bound to E-selectin

21 January 2018

1 reference

A single amino acid residue can determine the ligand specificity of E-selectin

21 January 2018

1 reference

Rational design and synthesis of small molecule, non-oligosaccharide selectin inhibitors: (alpha-D-mannopyranosyloxy)biphenyl-substituted carboxylic acids

21 January 2018

1 reference

Selectin-ligand interactions revealed by molecular dynamics simulation in solution

21 January 2018

1 reference

Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides

21 January 2018

1 reference

Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides

21 January 2018

1 reference

Studies on selectin blockers. 6. Discovery of homologous fucose sugar unit necessary for E-selectin binding

21 January 2018

1 reference

Design and synthesis of a new sialyl Lewis X mimetic: how selective are the selectin receptors?

21 January 2018

1 reference

Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity

21 January 2018

1 reference

Design and synthesis of sialyl Lewis x mimics as E-selectin inhibitors

21 January 2018

1 reference

Exploration of beta-turn scaffolding motifs as components of sialyl Le(X) mimetics and their relevance to P-selectin

21 January 2018

1 reference

Pharmacology of selectin inhibitors in ischemia/reperfusion states

21 January 2018

1 reference

Selectin inhibition: synthesis and evaluation of novel sialylated, sulfated and fucosylated oligosaccharides, including the major capping group of GlyCAM-1.

21 January 2018

1 reference

Synthesis and biological evaluation of a potent E-selectin antagonist

21 January 2018

1 reference

Synthesis and biological evaluation of a sialyl Lewis X mimic with significantly improved E-selectin inhibition

21 January 2018

1 reference

Synthesis of the C-glycoside analogue of a novel sialyl Lewis X mimetic

21 January 2018

1 reference

Spiroketal glycomimetics: the synthesis of a conformationally restrained Sialyl Lewis X mimic

21 January 2018

1 reference

Synthesis of E-selectin inhibitors: Use of an aryl-cyclohexyl ether as a disaccharide scaffold

21 January 2018

1 reference

Synthesis of novel 6-amido-6-deoxy-l-galactose derivatives as sialyl Lewis X mimetics

21 January 2018

1 reference

Isolation and characterization of natural protein-associated carbohydrate ligands for E-selectin

21 January 2018

1 reference

Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269).

21 January 2018

1 reference

Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction

21 January 2018

1 reference

Generation of C-Glycoside Peptide Ligands for Cell Surface Carbohydrate Receptors Using a Four-Component Condensation on Solid Support

21 January 2018

1 reference

Multivalent sialyl Lewis x ligands of definite structures as inhibitors of E-selectin mediated cell adhesion

21 January 2018

1 reference

Syntheses and some applications of chemically defined multivalent glycoconjugates

21 January 2018

1 reference

Polymerized liposome assemblies: bifunctional macromolecular selectin inhibitors mimicking physiological selectin ligands

21 January 2018

1 reference

Novel mimics of sialyl Lewis X: design, synthesis and biological activity of a series of 2- and 3-malonate substituted galactoconjugates

21 January 2018

1 reference

Peptide mimicking sialyl-Lewis(a) with anti-inflammatory activity

21 January 2018

1 reference

Beta-C-mannosides as selectin inhibitors

21 January 2018

1 reference

Stable-Isotope-Assisted NMR Studies on13C-Enriched Sialyl Lewisxin Solution and Bound to E-Selectin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.10018

1 reference

5 August 2017

1 reference