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Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila.
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3089465
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20 January 2020
title
Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila
(English)
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Europe PubMed Central
PMCID
3089465
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245036%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
main subject
Drosophila
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author
Klaus Förstemann
series ordinal
2
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Europe PubMed Central
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3089465
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245036%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
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Julia V Hartig
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1
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Europe PubMed Central
PMCID
3089465
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245036%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
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English
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17 January 2011
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3089465
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20 January 2020
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Nucleic Acids Research
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3089465
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20 January 2020
volume
39
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Europe PubMed Central
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3089465
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retrieved
20 January 2020
page(s)
3836-3851
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Europe PubMed Central
PMCID
3089465
reference URL
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20 January 2020
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9
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Europe PubMed Central
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3089465
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20 January 2020
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Creative Commons Attribution-NonCommercial 2.5 Generic
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4 October 2016
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cites work
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Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins
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Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila
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Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila
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Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
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Structure of the human Dicer-TRBP complex by electron microscopy
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Structural insights into RNA processing by the human RISC-loading complex
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RETRACTED: Identification of an RNA-dependent RNA polymerase in Drosophila involved in RNAi and transposon suppression
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8 July 2018
Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences
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8 July 2018
Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
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8 July 2018
Characterization of the TRBP domain required for dicer interaction and function in RNA interference
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8 July 2018
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
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Small RNAs as guardians of the genome
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8 July 2018
Biogenesis of small RNAs in animals
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8 July 2018
Small silencing RNAs: an expanding universe
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8 July 2018
An epigenetic role for maternally inherited piRNAs in transposon silencing
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8 July 2018
Endogenous small interfering RNAs in animals
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8 July 2018
Monitoring miRNA-mediated silencing in Drosophila melanogaster S2-cells
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8 July 2018
Autoinhibition of human dicer by its internal helicase domain
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8 July 2018
Endogenous RNA interference provides a somatic defense against Drosophila transposons
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8 July 2018
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster
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8 July 2018
Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
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PubMed Central
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8 July 2018
An endogenous small interfering RNA pathway in Drosophila
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PubMed Central
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8 July 2018
The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
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8 July 2018
Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
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8 July 2018
Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes
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PubMed Central
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8 July 2018
Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.
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8 July 2018
piRNAs--the ancient hunters of genome invaders
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8 July 2018
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
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8 July 2018
The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC.
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8 July 2018
CaSpeR5, a family of Drosophila transgenesis and shuttle vectors with improved multiple cloning sites
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8 July 2018
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
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8 July 2018
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
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8 July 2018
A distinct small RNA pathway silences selfish genetic elements in the germline
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PubMed Central
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8 July 2018
Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
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8 July 2018
RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
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8 July 2018
The role of PACT in the RNA silencing pathway
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
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8 July 2018
A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye
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8 July 2018
Evidence for maternally transmitted small interfering RNA in the repression of transposition in Drosophila virilis
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8 July 2018
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
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8 July 2018
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
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8 July 2018
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
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8 July 2018
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
1 reference
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8 July 2018
Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells
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8 July 2018
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
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8 July 2018
RISC assembly defects in the Drosophila RNAi mutant armitage.
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8 July 2018
Asymmetry in the assembly of the RNAi enzyme complex
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8 July 2018
R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway
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8 July 2018
bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
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8 July 2018
New and old roles of the double-stranded RNA-binding domain
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8 July 2018
The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans
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PubMed Central
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8 July 2018
ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos
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PubMed Central
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8 July 2018
The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)
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PubMed Central
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8 July 2018
Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression
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8 July 2018
Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs
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8 July 2018
TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR
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8 July 2018
Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR
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8 July 2018
Transposon defense in Drosophila somatic cells: a model for distinction of self and non-self in the genome.
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26 October 2018
Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway
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26 October 2018
Functional analysis of dicer-2 missense mutations in the siRNA pathway of Drosophila
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26 October 2018
Functional anatomy of the Drosophila microRNA-generating enzyme.
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26 October 2018
The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells.
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26 October 2018
A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
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26 October 2018
The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089465
retrieved
26 October 2018
Identifiers
DOI
10.1093/NAR/GKQ1324
1 reference
stated in
Europe PubMed Central
PMCID
3089465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PMCID
3089465
1 reference
stated in
Europe PubMed Central
PMCID
3089465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PubMed ID
21245036
1 reference
stated in
Europe PubMed Central
PMCID
3089465
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245036%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
ResearchGate publication ID
49765026
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