(Q34948285)

5 August 2017

title

Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype (English)

1 reference

5 August 2017

1 reference

Ariane Melchior-Becker

1

1 reference

5 August 2017

Guang Dai

2

1 reference

5 August 2017

Zhaoping Ding

3

1 reference

5 August 2017

Liliana Schäfer

4

1 reference

5 August 2017

Jürgen Schrader

5

1 reference

5 August 2017

Marian F Young

6

1 reference

5 August 2017

Jens W Fischer

7

1 reference

5 August 2017

language of work or name

English

0 references

publication date

18 March 2011

1 reference

5 August 2017

number of pages

11

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

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5 August 2017

volume

286

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5 August 2017

issue

19

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5 August 2017

page(s)

17365-17375

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describes a project that uses

5 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3089578/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis

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c-Ski, Smurf2, and Arkadia as regulators of TGF-beta signaling: new targets for managing myofibroblast function and cardiac fibrosis

8 July 2018

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Extracellular matrix turnover and signaling during cardiac remodeling following MI: causes and consequences.

8 July 2018

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Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Cardiac fibroblasts: at the heart of myocardial remodeling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

The potential functional interaction of biglycan and WISP-1 in controlling differentiation and proliferation of osteogenic cells

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion

8 July 2018

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Chronic ultraviolet B irradiation causes loss of hyaluronic acid from mouse dermis because of down-regulation of hyaluronic acid synthases

8 July 2018

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Formation and function of the myofibroblast during tissue repair

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

8 July 2018

1 reference

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Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Extracellular matrix glycoprotein biglycan enhances vascular smooth muscle cell proliferation and migration

8 July 2018

1 reference

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Biglycan knockout mice: new models for musculoskeletal diseases

8 July 2018

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Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial Cells

8 July 2018

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Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Myofibroblasts and mechano-regulation of connective tissue remodelling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Evidence for a role of the JNK cascade in Smad7-mediated apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Different usage of the glycosaminoglycan attachment sites of biglycan

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Infarct scar: a dynamic tissue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

IL-1 stimulates intestinal myofibroblast COX gene expression and augments activation of Cl- secretion in T84 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Mechanism of activation of the TGF-beta receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

The alpha-smooth muscle actin-positive cells in healing human myocardial scars

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Expression and role of cyclooxygenase isoforms in alveolar and peritoneal macrophages

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Regulation of collagen secretion by ascorbic acid in 3T3 and chick embryo fibroblasts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Temporal relationships of F-actin bundle formation, collagen and fibronectin matrix assembly, and fibronectin receptor expression to wound contraction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Fibroblasts modulate intestinal secretory responses to inflammatory mediators

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Fibroblast modulation of intestinal secretory responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Glycoprotein, elastin, and collagen secretion by rat smooth muscle cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Dependence of the differentiated state on the cellular environment: modulation of collagen synthesis in tendon cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Dermatan sulfate proteoglycan biglycan as a potential selectin L/CD44 ligand involved in selective recruitment of peripheral blood CD16(-) natural killer cells into human endometrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

A role for decorin in the remodeling of myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Biglycan is required for adaptive remodeling after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Nitric oxide-generating hydrogels inhibit neointima formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

An improved method for the collagen gel contraction assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Transforming growth factor-beta 1-mediated collagen gel contraction by cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Recombinant human decorin inhibits TGF-beta1-induced contraction of collagen lattice by hypertrophic scar fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Long-term treatment with the AT1-receptor antagonist telmisartan inhibits biglycan accumulation in murine atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.192682

Hyaluronan Used for Intradermal Injections Is Incorporated into the Pericellular Matrix and Promotes Proliferation in Human Skin Fibroblasts in vitro

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

Transforming growth factor-beta1 promotes contraction of collagen gel by cardiac fibroblasts through their differentiation into myofibroblasts

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089578

TGF-beta1, TGF-beta receptor II and ED-A fibronectin expression in myofibroblast of vitreoretinopathy

26 October 2018

1 reference

12 December 2020

Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells

1 reference

12 December 2020

Angiotensin converting enzyme and myofibroblasts during tissue repair in the rat heart

1 reference

12 December 2020

Critical Role of Glutamate in a Central Leucine-rich Repeat of Decorin for Interaction with Type I Collagen

1 reference

12 December 2020

Extracellular matrix remodeling in canine and mouse myocardial infarcts

1 reference

12 December 2020

CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response

1 reference

12 December 2020

Fibroblast migration is mediated by CD44-dependent TGF beta activation

1 reference

12 December 2020

Effects of biglycan deficiency on myocardial infarct structure and mechanics

1 reference

12 December 2020

Transcriptional and posttranscriptional regulators of biglycan in cardiac fibroblasts

1 reference

12 December 2020

Ascorbate-generated endogenous extracellular matrix affects cell protein synthesis in calf aortic smooth muscle cells

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.192682

1 reference

5 August 2017

1 reference

5 August 2017

1 reference