(Q34951563)

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Mitochondrial transcription factor A, an endogenous danger signal, promotes TNFα release via RAGE- and TLR9-responsive plasmacytoid dendritic cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Mitochondrial transcription factor A, an endogenous danger signal, promotes TNFα release via RAGE- and TLR9-responsive plasmacytoid dendritic cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

toll-like receptor

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1 reference

based on heuristic

inferred from title

author name string

Mark W Julian

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Guohong Shao

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Zachary C Vangundy

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Tracey L Papenfuss

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Elliott D Crouser

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

language of work or name

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publication date

12 August 2013

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Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

e72354

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 August 2013

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April 2022 Public Data File from Crossref

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0 references

Toll-like receptor 9 processing: the key event in Toll-like receptor 9 activation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3741150

8 July 2018

Mitochondria: master regulators of danger signalling

1 reference

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8 July 2018

Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3741150

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Mitochondrial transcription factor A is a proinflammatory mediator in hemorrhagic shock

1 reference

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Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma

1 reference

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DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature

1 reference

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Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE).

1 reference

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Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones

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Mitochondria in innate immune responses

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Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

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HMGB1 is a therapeutic target for sterile inflammation and infection

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Compartment-specific control of signaling from a DNA-sensing immune receptor.

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Type I IFN and TNFα cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance.

1 reference

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Type I interferon: friend or foe?

1 reference

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A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

1 reference

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Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands

1 reference

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8 July 2018

Intracellular toll-like receptors

1 reference

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8 July 2018

Circulating mitochondrial DAMPs cause inflammatory responses to injury

1 reference

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Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion

1 reference

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Endosomes: a legitimate platform for the signaling train

1 reference

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Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.

1 reference

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A genomic score prognostic of outcome in trauma patients

1 reference

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Late endosome/lysosome-localized Rab7b suppresses TLR9-initiated proinflammatory cytokine and type I IFN production in macrophages

1 reference

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Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3741150

8 July 2018

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3741150

8 July 2018

Antigen-presentation properties of plasmacytoid dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3741150

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PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

1 reference

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The systemic inflammatory response induced by trauma is reflected by multiple phenotypes of blood neutrophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3741150

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

1 reference

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Mitochondrial transcription factor A (TFAM): roles in maintenance of mtDNA and cellular functions

1 reference

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Human monocyte-derived dendritic cells express TLR9 and react directly to the CpG-A oligonucleotide D19.

1 reference

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Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis

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Submitochondrial localization of the mitochondrial isoform of folylpolyglutamate synthetase in CCRF-CEM human T-lymphoblastic leukemia cells

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Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR

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Plasmacytoid dendritic cells: linking innate and adaptive immunity

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

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1 reference

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1 reference

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Similarity of human mitochondrial transcription factor 1 to high mobility group proteins

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Identifiers

10.1371/JOURNAL.PONE.0072354

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

2013PLoSO...872354J

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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