(Q34957062)

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Three checkpoints in lupus development: central tolerance in adaptive immunity, peripheral amplification by innate immunity and end-organ inflammation

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scholarly article

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

Three checkpoints in lupus development: central tolerance in adaptive immunity, peripheral amplification by innate immunity and end-organ inflammation (English)

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Europe PubMed Central

5 August 2017

author name string

H Kanta

1

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Europe PubMed Central

5 August 2017

C Mohan

2

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Europe PubMed Central

5 August 2017

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5 March 2009

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Europe PubMed Central

5 August 2017

Genes and Immunity

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Europe PubMed Central

5 August 2017

10

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Europe PubMed Central

5 August 2017

5

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Europe PubMed Central

5 August 2017

390-396

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Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.1038/gene.2009.6

0 references

Genetic dissection of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Genetics of clinical expression in SLE.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Genetics of human systemic lupus erythematosus: the emerging picture

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https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Delineating the genetic basis of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Synovium as a source of increased amino-terminal parathyroid hormone-related protein expression in rheumatoid arthritis. A possible role for locally produced parathyroid hormone-related protein in the pathogenesis of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2.

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https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

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https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Genetics of systemic autoimmunity in mouse models of lupus

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https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Regulation of B cell tolerance by the lupus susceptibility gene Ly108.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Augmentation of NZB autoimmune phenotypes by the Sle1c murine lupus susceptibility interval.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Dendritic cells and the control of immunity

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Type I interferons in host defense

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Intracellular pattern recognition receptors in the host response

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The centromeric region of chromosome 7 from MRL mice (Lmb3) is an epistatic modifier of Fas for autoimmune disease expression.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Aberrant phenotype and function of myeloid dendritic cells in systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

A y chromosome associated factor in strain bxsb producing accelerated autoimmunity and lymphoproliferation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Effect of the BXSB Y chromosome accelerating gene on autoantibody production

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Disruption of mutually negative regulatory feedback loop between interferon-inducible p202 protein and the E2F family of transcription factors in lupus-prone mice

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Effects of MHC and gender on lupus-like autoimmunity in Nba2 congenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Antibodies to DNA.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Nephritogenic autoantibodies in lupus: current concepts and continuing controversies

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3).

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Familial occurrence of systemic vasculitis and rapidly progressive glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The familial risk of end-stage renal disease in African Americans

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Familial predisposition to nephropathy in African-Americans with non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Familial clustering of end-stage renal disease in blacks with lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Kidney disease in the first-degree relatives of African-Americans with hypertensive end-stage renal disease

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Experimental anti-GBM disease as a tool for studying spontaneous lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The genetics of SLE: an update in the light of genome-wide association studies

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Predominant autoantibody production by early human B cell precursors

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Defective B cell tolerance checkpoints in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

PTPN22: setting thresholds for autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Polygenic control of susceptibility to murine systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

21 January 2018

Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

CD19 hyperexpression augments Sle1-induced humoral autoimmunity but not clinical nephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic susceptibility to systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

The Y chromosome from autoimmune BXSB/MpJ mice induces a lupus-like syndrome in (NZW x C57BL/6)F1 male mice, but not in C57BL/6 male mice

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Epistatic modifiers of autoimmunity in a murine model of lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

PD-1: an inhibitory immunoreceptor involved in peripheral tolerance

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2009.6

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/GENE.2009.6

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Europe PubMed Central

5 August 2017

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1 reference

Europe PubMed Central

5 August 2017

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