(Q34979739)

5 August 2017

1 reference

title

Rate of generation of oxidative stress-related damage and animal longevity (English)

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5 August 2017

Gustavo Barja

1

1 reference

5 August 2017

1 November 2002

1 reference

Free Radical Biology and Medicine

5 August 2017

1 reference

5 August 2017

33

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5 August 2017

9

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5 August 2017

1167-1172

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Aging: a theory based on free radical and radiation chemistry

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

The biologic clock: the mitochondria?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

The free radical theory of aging matures

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Relationship between antioxidant defenses and longevity in different mammalian species

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Effect of Antioxidants on Life-Span of C57BL Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Effects of the Antioxidant Butylated Hydroxytoluene (BHT) on Mortality in BALB/c Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

alpha-Tocopherol increases lifespan in the rotifer Philodina

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

The effect of simultaneous administration of tocopherol and sunflower oil on the life-span of female mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Effects of the type of dietary fat at two levels of vitamin E in Wistar male rats during development and aging. I. Life span, serum biochemical parameters and pathological changes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Dietary restriction alone and in combination with oral ethoxyquin/2-mercaptoethylamine in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Brain glutathione reductase induction increases early survival and decreases lipofuscin accumulation in aging frogs.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Simultaneous induction of SOD, glutathione reductase, GSH, and ascorbate in liver and kidney correlates with survival during aging

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Susceptibility of heterozygous MnSOD gene-knockout mice to oxygen toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Targeted deletion of the cytosolic Cu/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Mitochondrial disease in superoxide dismutase 2 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

The comparative biology of longevity and lifetime energetics.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

8-oxo-deoxyguanosine levels in heart and brain mitochondrial and nuclear DNA of two mammals and three birds in relation to their different rates of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus)

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Effect of aging on mitochondrial and nuclear DNA oxidative damage in the heart and brain throughout the life-span of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Membrane fatty acid composition of tissues is related to body mass of mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: the pigeon and human case.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900910-3

7 January 2021

10.1016/S0891-5849(02)00910-3

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12398924