(Q34980375)

English

Contribution of protein binding to the pharmacokinetics of the ghrelin receptor agonist TZP-101 in healthy volunteers and adults with symptomatic gastroparesis: two randomized, double-blind studies and a binding profile study

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Contribution of protein binding to the pharmacokinetics of the ghrelin receptor agonist TZP-101 in healthy volunteers and adults with symptomatic gastroparesis: two randomized, double-blind studies and a binding profile study (English)

1 reference

Europe PubMed Central

5 August 2017

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

William Wargin

1

1 reference

Europe PubMed Central

5 August 2017

Helmut Thomas

2

1 reference

Europe PubMed Central

5 August 2017

Lilian Clohs

3

1 reference

Europe PubMed Central

5 August 2017

Carl St-Louis

4

1 reference

Europe PubMed Central

5 August 2017

Niels Ejskjaer

5

1 reference

Europe PubMed Central

5 August 2017

Maria Gutierrez

6

1 reference

Europe PubMed Central

5 August 2017

Laura Shaughnessy

7

1 reference

Europe PubMed Central

5 August 2017

Gordana Kosutic

8

1 reference

Europe PubMed Central

5 August 2017

publication date

1 January 2009

1 reference

Europe PubMed Central

5 August 2017

Clinical Drug Investigation

1 reference

Europe PubMed Central

5 August 2017

29

1 reference

Europe PubMed Central

5 August 2017

6

1 reference

Europe PubMed Central

5 August 2017

409-418

1 reference

Europe PubMed Central

5 August 2017

Altered pharmacokinetics of a novel anticancer drug, UCN-01, caused by specific high affinity binding to alpha1-acid glycoprotein in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prokinetic effects of a new ghrelin receptor agonist TZP-101 in a rat model of postoperative ileus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin gastrokinetic action in patients with neurogenic gastroparesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical practice. Diabetic gastroparesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of gastroparesis: a multidisciplinary clinical review

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution and plasma pharmacokinetics of UCN-01 at steady-state and following bolus administration in rats: influence of human alpha1-acid glycoprotein binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential binding of disopyramide and warfarin enantiomers to human alpha(1)-acid glycoprotein variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alpha1-acid glycoprotein on the clinical pharmacokinetics of 7-hydroxystaurosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone secretagogues derived from NN703 with hydrazidesas c-terminal

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interspecies differences in plasma protein binding of MS-275, a novel histone deacetylase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of ghrelin on gastric emptying and meal-related symptoms in idiopathic gastroparesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin enhances gastric motility through direct stimulation of intrinsic neural pathways and capsaicin-sensitive afferent neurones in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in protein binding of drugs: implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin agonist (TZP-101): safety, pharmacokinetics and pharmacodynamic evaluation in healthy volunteers: a phase I, first-in-human study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of UCN-01 development: a lesson in the importance of clinical pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered glycosylation of alpha1-acid glycoprotein in patients with inflammation and diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin stimulates motility in the small intestine of rats through intrinsic cholinergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular functional study on the interactions of drugs with plasma proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged postoperative ileus-definition, risk factors, and predictors after surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-1-acid glycoprotein concentration and the protein binding of disopyramide in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin receptor agonist (TZP-101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19432500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00044011-200929060-00004

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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