(Q34980492)

5 August 2017

1 reference

title

Detecting gene-gene interactions that underlie human diseases (English)

1 reference

5 August 2017

Heather J Cordell

1

1 reference

5 August 2017

publication date

1 June 2009

1 reference

5 August 2017

published in

Nature Reviews Genetics

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5 August 2017

volume

10

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5 August 2017

issue

6

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5 August 2017

page(s)

392-404

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Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis

5 August 2017

cites work

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Using biological networks to search for interacting loci in genome-wide association studies

8 July 2018

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8 July 2018

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

8 July 2018

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A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies

8 July 2018

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A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis

8 July 2018

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Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies

8 July 2018

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Tests for gene-environment interaction from case-control data: a novel study of type I error, power and designs

8 July 2018

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Pattern-based mining strategy to detect multi-locus association and gene x environment interaction

8 July 2018

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From classical genetics to quantitative genetics to systems biology: modeling epistasis

8 July 2018

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A complete classification of epistatic two-locus models

8 July 2018

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Genome-wide prediction of functional gene-gene interactions inferred from patterns of genetic differentiation in mice and men.

8 July 2018

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An ensemble learning approach jointly modeling main and interaction effects in genetic association studies

8 July 2018

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Information-theoretic metrics for visualizing gene-environment interactions

8 July 2018

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TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

8 July 2018

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8 July 2018

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Detecting association using epistatic information

8 July 2018

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A whole-genome association study of major determinants for host control of HIV-1

8 July 2018

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Evaporative cooling feature selection for genotypic data involving interactions

8 July 2018

1 reference

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Allelic association studies of genome wide association data can reveal errors in marker position assignments

8 July 2018

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

8 July 2018

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

8 July 2018

1 reference

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Genome-wide association study identifies novel breast cancer susceptibility loci

8 July 2018

1 reference

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A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence

8 July 2018

1 reference

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

8 July 2018

1 reference

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A unified model for functional and statistical epistasis and its application in quantitative trait Loci analysis.

8 July 2018

1 reference

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Bias in random forest variable importance measures: illustrations, sources and a solution

8 July 2018

1 reference

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Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Test for interaction between two unlinked loci

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Machine learning for detecting gene-gene interactions: a review

8 July 2018

1 reference

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A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

8 July 2018

1 reference

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GPNN: power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease

8 July 2018

1 reference

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A testing framework for identifying susceptibility genes in the presence of epistasis

8 July 2018

1 reference

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A novel method to identify gene-gene effects in nuclear families: the MDR-PDT.

8 July 2018

1 reference

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Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis

8 July 2018

1 reference

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Modeling quantitative trait Loci and interpretation of models

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Screening large-scale association study data: exploiting interactions using random forests

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Computational analysis of gene-gene interactions using multifactor dimensionality reduction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Detecting epistatic interactions contributing to quantitative traits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Mathematical multi-locus approaches to localizing complex human trait genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

New strategies for identifying gene-gene interactions in hypertension

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

A perspective on epistasis: limits of models displaying no main effect

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Selecting SNPs in two-stage analysis of disease association data: a model-free approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Choosing a retrospective design to assess joint genetic and environmental contributions to risk

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Multilocus linkage tests based on affected relative pairs.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Case-only design to measure gene-gene interaction.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

The language of gene interaction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Epistasis and its contribution to genetic variance components.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Biological Models and Statistical Interactions: an Example from Multistage Carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Effect modification and the limits of biological inference from epidemiologic data.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Two-locus models of disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Interactions in epidemiology: relevance, identification, and estimation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Sufficient cause interactions and statistical interactions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

RET Gly691Ser mutation is associated with primary vesicoureteral reflux in the French-Canadian population from Quebec.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Comparison of approaches for machine-learning optimization of neural networks for detecting gene-gene interactions in genetic epidemiology

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Sample size requirements for indirect association studies of gene-environment interactions (G x E).

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Exploiting gene-environment independence for analysis of case-control studies: an empirical Bayes-type shrinkage estimator to trade-off between bias and efficiency

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Detecting high-order interactions of single nucleotide polymorphisms using genetic programming

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

An entropy-based approach for testing genetic epistasis underlying complex diseases

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Exploration of gene-gene interaction effects using entropy-based methods.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Bayesian inference of epistatic interactions in case-control studies.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Allelic penetrance approach as a tool to model two-locus interaction in complex binary traits

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Identification of a two-loci epistatic interaction associated with susceptibility to rheumatoid arthritis through reverse engineering and multifactor dimensionality reduction.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Penalized logistic regression for detecting gene interactions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

A Bayesian toolkit for genetic association studies.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Variance component analysis of polymorphic metabolic systems

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Genome-wide strategies for detecting multiple loci that influence complex diseases.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene-gene and gene-environment interactions, and parent-of-origin effects.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Sample size requirements for association studies of gene-gene interaction

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Sequence analysis using logic regression.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Use of classification trees for association studies

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Epistasis and pleiotropy as natural properties of transcriptional regulation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Renin–angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: Detection of high order gene–gene interaction

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Identifying SNPs predictive of phenotype using random forests

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

MDR and PRP: A Comparison of Methods for High-Order Genotype-Phenotype Associations

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872761

Exploiting gene-environment interaction to detect genetic associations

9 December 2018

1 reference

The Correlation between Relatives on the Supposition of Mendelian Inheritance

31 March 2020

1 reference

How to model a complex trait. 2. Analysis with two disease loci

31 March 2020

1 reference

Statistical Methods in Medical Research

31 March 2020

1 reference

A complete enumeration and classification of two-locus disease models

31 March 2020

1 reference

Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies

31 March 2020

1 reference

Case-Only Design to Measure Gene-Gene Interaction

31 March 2020

1 reference

Strategy for Detecting Susceptibility Genes with Weak or No Marginal Effect

31 March 2020

1 reference

Generalized Cross-Validation as a Method for Choosing a Good Ridge Parameter

31 March 2020

1 reference

Ridge Estimators in Logistic Regression

31 March 2020

1 reference

31 March 2020

Least angle regression

1 reference

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

31 March 2020

1 reference

Identifying interacting SNPs using Monte Carlo logic regression

31 March 2020

1 reference

Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions

31 March 2020

1 reference

Tuning ReliefF for Genome-Wide Genetic Analysis

31 March 2020

1 reference

Bayesian analysis of allelic penetrance models for complex binary traits

31 March 2020

1 reference

Generalized Linear Models

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRG2579

1 reference

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference