(Q34992939)

5 August 2017

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title

Other transcription factors and hypopituitarism (English)

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5 August 2017

Laurie E Cohen

1

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5 August 2017

Sally Radovick

series ordinal

2

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5 August 2017

publication date

1 December 2002

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Reviews in Endocrine and Metabolic Disorders

5 August 2017

published in

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5 August 2017

volume

3

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5 August 2017

issue

4

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5 August 2017

page(s)

301-311

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https://scigraph.springernature.com/pub.10.1023/a:1020997423195

5 August 2017

exact match

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12 December 2020

Functional analyses of two newly identified PITX2 mutants reveal a novel molecular mechanism for Axenfeld-Rieger syndrome

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12 December 2020

NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene

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12 December 2020

Defective retinoic acid regulation of the Pit-1 gene enhancer: a novel mechanism of combined pituitary hormone deficiency

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12 December 2020

Dosage requirement of Pitx2 for development of multiple organs

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12 December 2020

Combined pituitary hormone deficiency caused by a novel mutation of a highly conserved residue (F88S) in the homeodomain of PROP-1

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12 December 2020

Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival

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12 December 2020

A novel E250X mutation of the PIT1 gene in a patient with combined pituitary hormone deficiency

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12 December 2020

Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility

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12 December 2020

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

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12 December 2020

Transcription Factors and Hypopituitarism

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12 December 2020

LHX3 transcription factor mutations associated with combined pituitary hormone deficiency impair the activation of pituitary target genes

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12 December 2020

A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally

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12 December 2020

Function of Rieger syndrome gene in left-right asymmetry and craniofacial development

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12 December 2020

Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism

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12 December 2020

How many homeobox genes does it take to make a pituitary gland?

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12 December 2020

Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain

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12 December 2020

Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development.

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12 December 2020

The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities

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12 December 2020

Specification of pituitary cell lineages by the LIM homeobox gene Lhx3

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12 December 2020

Otlx2, an Otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain

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12 December 2020

Linkage mapping of the gene for the LIM-homeoprotein LIM3 (locus Lhx3) to mouse Chromosome 2

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12 December 2020

The homeodomain protein, Pit-1/GHF-1, is capable of binding to and activating cell-specific elements of both the growth hormone and prolactin gene promoters

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12 December 2020

Combined pituitary hormone deficiency caused by compound heterozygosity for two novel mutations in the POU domain of the Pit1/POU1F1 gene

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12 December 2020

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions

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12 December 2020

Pituitary-directed leukemia inhibitory factor transgene causes Cushing's syndrome: neuro-immune-endocrine modulation of pituitary development

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12 December 2020

Longitudinal imaging reveals pituitary enlargement preceding hypoplasia in two brothers with combined pituitary hormone deficiency attributable to PROP1 mutation

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12 December 2020

Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain

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12 December 2020

Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia

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12 December 2020

Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis

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12 December 2020

Heritable disorders of pituitary development

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12 December 2020

Identification of a dominant negative homeodomain mutation in Rieger syndrome

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12 December 2020

Genomic structure, chromosomal localization, and expression pattern of the human LIM-homeobox3 (LHX 3) gene

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12 December 2020

The Ames dwarf gene, df, is required early in pituitary ontogeny for the extinction of Rpx transcription and initiation of lineage-specific cell proliferation.

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12 December 2020

A new mutation of the gene encoding the transcription factor Pit-1 is responsible for combined pituitary hormone deficiency.

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12 December 2020

Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription

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12 December 2020

Cretinism with combined hormone deficiency caused by a mutation in the PIT1 gene

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12 December 2020

Adrenocorticotropin deficiency in combined pituitary hormone deficiency patients homozygous for a novel PROP1 deletion

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12 December 2020

Syndromic short stature in patients with a germline mutation in the LIM homeobox LHX4.

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12 December 2020

The PROP1 2-base pair deletion is a common cause of combined pituitary hormone deficiency

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12 December 2020

Pro239Ser: a novel recessive mutation of the Pit-1 gene in seven Middle Eastern children with growth hormone, prolactin, and thyrotropin deficiency

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12 December 2020

A new step understood in the cascade of tissue-specific regulators orchestrating pituitary lineage determination: the Prophet of Pit-1 (Prop-1).

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12 December 2020

Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family

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12 December 2020

A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency

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12 December 2020

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

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12 December 2020

Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19.

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12 December 2020

The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3.

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12 December 2020

Clinical and biochemical phenotype of familial anterior hypopituitarism from mutation of the PROP1 gene

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12 December 2020

Role of GHF-1 in the regulation of the rat growth hormone gene promoter by thyroid hormone and retinoic acid receptors

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12 December 2020

Multistep signaling requirements for pituitary organogenesis in vivo

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12 December 2020

Multistep control of pituitary organogenesis.

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12 December 2020

Dissection of functional domains of the pituitary-specific transcription factor GHF-1.

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12 December 2020

A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins

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12 December 2020

Mutations in PROP1 cause familial combined pituitary hormone deficiency

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12 December 2020

P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development

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12 December 2020

A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene.

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12 December 2020

Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome

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12 December 2020

Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor

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12 December 2020

Pitx2 determines left-right asymmetry of internal organs in vertebrates.

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12 December 2020

Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors

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12 December 2020

Phenotypic variability in familial combined pituitary hormone deficiency caused by a PROP1 gene mutation resulting in the substitution of Arg-->Cys at codon 120 (R120C)

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12 December 2020

Compound heterozygous deletion of the PROP-1 gene in children with combined pituitary hormone deficiency

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12 December 2020

A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons

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12 December 2020

The PTX family of homeodomain transcription factors during pituitary developments.

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12 December 2020

A mutational hot spot in the Prop-1 gene in Russian children with combined pituitary hormone deficiency

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12 December 2020

Mutations in the Pit-1 gene in children with combined pituitary hormone deficiency

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12 December 2020

Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope.

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12 December 2020

A model for the development of the hypothalamic-pituitary axis: transcribing the hypophysis

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12 December 2020

Human Prop-1: cloning, mapping, genomic structure. Mutations in familial combined pituitary hormone deficiency

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12 December 2020

Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency

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12 December 2020

A "hot spot" in the Pit-1 gene responsible for combined pituitary hormone deficiency: clinical and molecular correlates.

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12 December 2020

Impaired adrenocorticotropin-adrenal axis in combined pituitary hormone deficiency caused by a two-base pair deletion (301-302delAG) in the prophet of Pit-1 gene

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12 December 2020

The Ames dwarf gene is required for Pit-1 gene activation.

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12 December 2020

Expression of GHF-1 protein in mouse pituitaries correlates both temporally and spatially with the onset of growth hormone gene activity

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12 December 2020

Ligand-dependent, Pit-1/growth hormone factor-1 (GHF-1)-independent transcriptional stimulation of rat growth hormone gene expression by thyroid hormone receptors in vitro

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12 December 2020

Longitudinal hormonal and pituitary imaging changes in two females with combined pituitary hormone deficiency due to deletion of A301,G302 in the PROP1 gene

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12 December 2020

Central hypothyroidism reveals compound heterozygous mutations in the Pit-1 gene

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12 December 2020

Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues

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12 December 2020

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

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12 December 2020

Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development

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12 December 2020

The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis

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12 December 2020

Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene

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12 December 2020

Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation.

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12 December 2020

Synergistic activation of the rat growth hormone promoter by Pit-1 and the thyroid hormone receptor

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12 December 2020

Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression

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12 December 2020

Combined pituitary hormone deficiency due to the F135C human Pit-1 (pituitary-specific factor 1) gene mutation: functional and structural correlates

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12 December 2020

P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1.

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12 December 2020

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.

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12 December 2020

Identifiers

DOI

10.1023/A:1020997423195

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Dimensions Publication ID

5 August 2017

1011233747

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