(Q34995405)

5 August 2017

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title

Recent advances in the brain-to-blood efflux transport across the blood-brain barrier (English)

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5 August 2017

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Ken-ichi Hosoya

1

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5 August 2017

Sumio Ohtsuki

series ordinal

2

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5 August 2017

Tetsuya Terasaki

series ordinal

3

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5 August 2017

language of work or name

English

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publication date

1 November 2002

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International Journal of Pharmaceutics

5 August 2017

published in

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5 August 2017

volume

248

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5 August 2017

issue

1-2

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5 August 2017

page(s)

15-29

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Neurotransmitter transporters: three distinct gene families.

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Newly developed rat brain pericyte cell line, TR-PCT1, responds to transforming growth factor-beta1 and beta-glycerophosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Polarity of the Blood-Brain Barrier: Neutral Amino Acid Transport into Isolated Brain Capillaries

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Gene expression of taurine transporter and taurine biosynthetic enzymes in brain of rats with acute or chronic hyperosmotic plasma. A comparative study with gene expression of myo-inositol transporter, betaine transporter and sorbitol biosynthetic e

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

A one-step procedure for isolation of poly(A)+ mRNA from isolated brain capillaries and endothelial cells in culture

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

GABA transporter heterogeneity: pharmacology and cellular localization

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Coculture of astroglial and vascular endothelial cells as apposing layers enhances the transcellular transport of hypoxanthine.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Uptake and efflux of the peptidic delta-opioid receptor agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Brain-to-blood efflux transport of estrone-3-sulfate at the blood-brain barrier in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

mRna expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Astrocytes induce blood–brain barrier properties in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

In vivo evidence for brain-to-blood efflux transport of valproic acid across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Efflux of a suppressive neurotransmitter, GABA, across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain

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https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Blood—Brain Barrier Genomics

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Oatp2 mediates bidirectional organic solute transport: a role for intracellular glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve: in vivo evidence for two distinct astrocyte lineages

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Conditionally immortalized cell lines with differentiated functions established from temperature-sensitive T-antigen transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Na(+)-dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) of the blood-brain barrier. A mechanism for glutamate removal

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Phenobarbital and phenytoin in neonatal seizures: metabolism and tissue distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Blood-brain barrier biology and methodology

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Vector-mediated drug delivery to the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Fine structural localization of a blood-brain barrier to exogenous peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Neutral amino acid transport characterization of isolated luminal and abluminal membranes of the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

The multispecific organic anion transporter (OAT) family.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Establishment of SV40-tsA58 transgenic rats as a source of conditionally immortalized cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

GAT2/BGT-1 as a system responsible for the transport of gamma-aminobutyric acid at the mouse blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

cDNA cloning and functional characterization of rat intestinal monocarboxylate transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

The blood-brain barrier efflux transporters as a detoxifying system for the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Conditionally immortalized cell lines as a new in vitro model for the study of barrier functions.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Restricted transport of 3'-azido-3'-deoxythymidine and dideoxynucleosides through the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Acidic amino acid transport characteristics of a newly developed conditionally immortalized rat type 2 astrocyte cell line (TR-AST).

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Cloning and functional identification of a neuronal glutamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Localization of norepinephrine and serotonin transporter in mouse brain capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Actions of dehydroepiandrosterone and its sulfate in the central nervous system: effects on cognition and emotion in animals and humans

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Vascular pericytes not only regulate growth, but also preserve prostacyclin-producing ability and protect against lipid peroxide-induced injury of co-cultured endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

Rapid transferrin efflux from brain to blood across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0378-5173%2802%2900457-X

7 January 2021

10.1016/S0378-5173(02)00457-X

Identifiers

DOI

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5 August 2017

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