(Q34996620)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

review article

1 reference

title

Diabetic flies? Using Drosophila melanogaster to understand the causes of monogenic and genetically complex diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

main subject

Drosophila melanogaster

0 references

author

Paul Lasko

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

author name string

Lasko P

series ordinal

1

1 reference

5 August 2017

publication date

1 November 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

volume

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

page(s)

358-367

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis

14 December 2019

cites work

1 reference

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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

1 reference

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Identification and characterization of the tuberous sclerosis gene on chromosome 16

21 January 2018

1 reference

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Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein

21 January 2018

1 reference

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The Drosophila melanogaster homologue of the Xeroderma pigmentosum D gene product is located in euchromatic regions and has a dynamic response to UV light-induced lesions in polytene chromosomes

21 January 2018

1 reference

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Comparative genomics of the eukaryotes

21 January 2018

1 reference

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7 January 2021

A survey of human disease gene counterparts in the Drosophila genome

1 reference

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7 January 2021

A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster

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7 January 2021

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

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7 January 2021

Genetic dissection of a neurodevelopmental pathway: Son of sevenless functions downstream of the sevenless and EGF receptor tyrosine kinases

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7 January 2021

Progress and variations in two-hybrid and three-hybrid technologies

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7 January 2021

The continuing epidemic of obesity in the United States

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7 January 2021

Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

1 reference

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7 January 2021

Development of the multiple metabolic syndrome in the ARIC cohort: joint contribution of insulin, BMI, and WHR. Atherosclerosis risk in communities

1 reference

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7 January 2021

Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.

1 reference

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7 January 2021

Hypertriglyceridemia, insulin resistance, and the metabolic syndrome

1 reference

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7 January 2021

Insulin resistance: definition and consequences

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

1 reference

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7 January 2021

A homozygous kinase-defective mutation in the insulin receptor gene in a patient with leprechaunism

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Four mutant alleles of the insulin receptor gene associated with genetic syndromes of extreme insulin resistance

1 reference

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7 January 2021

Two aberrant splicings caused by mutations in the insulin receptor gene in cultured lymphocytes from a patient with Rabson-Mendenhall's syndrome

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective postreceptor insulin resistance

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Cardiovascular risk continuum: implications of insulin resistance and diabetes.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Germline mutations in PTEN are present in Bannayan-Zonana syndrome

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The genetic basis of tuberous sclerosis.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Morphogenetic mutants detected in mitotic recombination clones

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Genetic pathways that regulate ageing in model organisms

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Flies, genes, learning, and memory

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Genetic studies of spectrin: new life for a ghost protein.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Nitric oxide and cyclic GMP regulate retinal patterning in the optic lobe of Drosophila.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Epithelial cell polarity and cell junctions in Drosophila

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The ryanodine receptor is essential for larval development in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The dystrophin / utrophin homologues in Drosophila and in sea urchin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

A thrombospondin homologue in Drosophila melanogaster: cDNA and protein structure.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

The antidepressant-sensitive dopamine transporter in Drosophila melanogaster: a primordial carrier for catecholamines.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Drosophila dumpy is a gigantic extracellular protein required to maintain tension at epidermal-cuticle attachment sites

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Hedgehog signaling in animal development: paradigms and principles

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Model organisms: new insights into ion channel and transporter function. L-type calcium channels regulate epithelial fluid transport in Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

DNA repair in Drosophila: insights from the Drosophila genome sequence.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Transforming growth factor beta signaling mediators and modulators

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Genghis Khan (Gek) as a putative effector for Drosophila Cdc42 and regulator of actin polymerization

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-0004.2002.620502.X

7 January 2021

10.1034/J.1399-0004.2002.620502.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12431248%20AND%20SRC:MED&resulttype=core&format=json

release_m64kncpa5zevjdfp4jzr7w5lr4

14 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/m64kncpa5zevjdfp4jzr7w5lr4

24 November 2022

mapped directly with Wikidata item

1 reference