(Q34997371)

5 August 2017

title

Rational discovery of novel nuclear hormone receptor antagonists (English)

1 reference

5 August 2017

M Schapira

1

1 reference

5 August 2017

B M Raaka

series ordinal

2

1 reference

5 August 2017

H H Samuels

series ordinal

3

1 reference

5 August 2017

R Abagyan

series ordinal

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 February 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

1 reference

5 August 2017

volume

97

1 reference

5 August 2017

issue

3

1 reference

5 August 2017

page(s)

1008-1013

1 reference

NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Future trends: a new generation of retinoids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

RARalpha antagonist Ro 41-5253 inhibits proliferation and induces apoptosis in breast-cancer cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Atomic structure of progesterone complexed with its receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Conformational adaptation of agonists to the human nuclear receptor RAR gamma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Flexible protein-ligand docking by global energy optimization in internal coordinates.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Molecular basis of agonism and antagonism in the oestrogen receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Dopamine neuron agenesis in Nurr1-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

RU486 (mifepristone): mechanisms of action and clinical uses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Identification of a retinoic acid receptor alpha subtype specific agonist

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Molecular docking programs successfully predict the binding of a beta-lactamase inhibitory protein to TEM-1 beta-lactamase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Detailed ab initio prediction of lysozyme-antibody complex with 1.6 A accuracy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.3.1008

The nuclear receptor ligand-binding domain: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.3.1008

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.3.1008

Apoptosis induction and potent antiestrogen receptor-negative breast cancer activity in vivo by a retinoid antagonist.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15503

Recent advances in systemic therapy for breast cancer

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.3.1008

A canonical structure for the ligand-binding domain of nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.3.1008

Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.3.1008

Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10655475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

EM-800, a novel antiestrogen, acts as a pure antagonist of the transcriptional functions of estrogen receptors alpha and beta

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10655475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10655475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.97.3.1008

1 reference

journals/pnas/SchapiraRSA00

5 August 2017

0 references

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

5 August 2017

1 reference