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Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
title
Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
main subject
hemopoiesis
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author
Ivan Maillard
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
author name string
Stephanie Y Jo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
Eric M Granowicz
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
Dafydd Thomas
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
Jay L Hess
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
language of work or name
English
0 references
publication date
25 February 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
published in
Blood
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
117
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
issue
18
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
page(s)
4759-4768
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
cites work
Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes
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PubMed Central
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MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia
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Early mammalian erythropoiesis requires the Dot1L methyltransferase
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PubMed Central
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8 July 2018
Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development
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Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)
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Misguided transcriptional elongation causes mixed lineage leukemia
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Menin regulates the function of hematopoietic stem cells and lymphoid progenitors
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H3K79 methylation profiles define murine and human MLL-AF4 leukemias
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The PHD fingers of MLL block MLL fusion protein-mediated transformation
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The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure
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Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.
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DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells
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8 July 2018
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia
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8 July 2018
A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification
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8 July 2018
The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling
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8 July 2018
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model
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8 July 2018
Profile of histone lysine methylation across transcribed mammalian chromatin
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8 July 2018
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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8 July 2018
hDOT1L links histone methylation to leukemogenesis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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8 July 2018
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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8 July 2018
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization
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PubMed Central
reference URL
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8 July 2018
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
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8 July 2018
Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
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8 July 2018
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain
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PubMed Central
reference URL
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8 July 2018
Dot1p modulates silencing in yeast by methylation of the nucleosome core
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PubMed Central
reference URL
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8 July 2018
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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8 July 2018
Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae
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8 July 2018
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
1 reference
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PubMed Central
reference URL
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8 July 2018
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.
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8 July 2018
Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis.
1 reference
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8 July 2018
The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.
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26 October 2018
The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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26 October 2018
ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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26 October 2018
New insights to the MLL recombinome of acute leukemias
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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26 October 2018
A reliable lacZ expression reporter cassette for multipurpose, knockout-first alleles
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3100687
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26 October 2018
Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21398221
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1182/BLOOD-2010-12-327668
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PMC publication ID
3100687
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed publication ID
21398221
1 reference
stated in
Europe PubMed Central
PMC publication ID
3100687
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398221%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
ResearchGate publication ID
50376403
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