(Q35012075)

5 August 2017

1 reference

title

Regulation of early lymphocyte development by E2A family proteins (English)

1 reference

5 August 2017

Stephen Greenbaum

1

1 reference

PubMed ID

12457613

5 August 2017

Yuan Zhuang

series ordinal

2

1 reference

5 August 2017

1 December 2002

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5 August 2017

Seminars in Immunology

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5 August 2017

14

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5 August 2017

405-414

1 reference

5 August 2017

6

1 reference

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

B-cell-specific DNA binding by an E47 homodimer

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

An intermolecular disulfide bond stabilizes E2A homodimers and is required for DNA binding at physiological temperatures

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Phosphorylation of E47 as a potential determinant of B-cell-specific activity

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Two isoforms of protein disulfide isomerase alter the dimerization status of E2A proteins by a redox mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

The basic helix-loop-helix transcription factor E2-2 is involved in T lymphocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Both E12 and E47 allow commitment to the B cell lineage

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Functional replacement of the mouse E2A gene with a human HEB cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Localization of E2A mRNA expression in developing and adult rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Restricted expression of E2A protein in primary human tissues correlates with proliferation and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Pan/E2A expression precedes immunoglobulin heavy-chain expression during B lymphopoiesis in nontransformed cells, and Pan/E2A proteins are not detected in myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Early thymocyte development is regulated by modulation of E2A protein activity

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Post-transcriptional regulation of E2A proteins via lipopolysaccharide and CD40 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Constitutive expression of the Id1 gene impairs mouse B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Development of the primary antibody repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Identification and characterization of two functional domains within the murine heavy-chain enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Repression of the immunoglobulin heavy chain 3' enhancer by helix-loop-helix protein Id3 via a functionally important E47/E12 binding site: implications for developmental control of enhancer function.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

E47 activates the Ig-heavy chain and TdT loci in non-B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Terminal deoxynucleotidyl transferase and repertoire development

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Promotion of cell cycle progression by basic helix-loop-helix E2A

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Failure of B-cell differentiation in mice lacking the transcription factor EBF.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Overlapping expression of early B-cell factor and basic helix-loop-helix proteins as a mechanism to dictate B-lineage-specific activity of the lambda5 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

E2A and HEB activate the pre-TCR alpha promoter during immature T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Positive and negative regulation of V(D)J recombination by the E2A proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.

1 reference

https://api.crossref.org/works/10.1016%2FS1044532302000751

7 January 2021

10.1016/S1044532302000751

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12457613