(Q35013225)

5 August 2017

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title

Polyoma virus middle T antigen and its role in identifying cancer-related molecules (English)

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5 August 2017

Stephen M Dilworth

1

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PubMed ID

12459733

5 August 2017

language of work or name

English

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publication date

1 December 2002

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5 August 2017

Nature Reviews Cancer

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5 August 2017

2

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5 August 2017

12

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5 August 2017

951-956

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https://scigraph.springernature.com/pub.10.1038/nrc946

5 August 2017

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cites work

A filterable agent, recovered from Ak leukemic extracts, causing salivary gland carcinomas in C3H mice

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Host range mutants of polyoma virus

31 March 2020

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CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS

31 March 2020

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Complementation and transformation by temperature-sensitive mutants of polyoma virus

31 March 2020

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Characterization of polyoma virus T antigen

31 March 2020

1 reference

Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus

31 March 2020

1 reference

Characterization of t antigens in polyoma-infected and transformed cells

31 March 2020

1 reference

Tumor antigen(s) in cells productively infected by wild-type polyoma virus and mutant NG-18

31 March 2020

1 reference

Tumor antigens induced by nontransforming mutants of polyoma virus

31 March 2020

1 reference

Three species of polyoma virus tumor antigens share common peptides probably near the amino termini of the proteins

31 March 2020

1 reference

Translation of polyoma virus T antigens in vitro

31 March 2020

1 reference

Coding potential and regulatory signals of the polyoma virus genome

31 March 2020

1 reference

Requirement for the C-terminal region of middle T-antigen in cellular transformation by virus

31 March 2020

1 reference

Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation

31 March 2020

1 reference

T antigen is bound to a host protein in SY40-transformed cells

31 March 2020

1 reference

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

31 March 2020

1 reference

Live or let die: the cell's response to p53

31 March 2020

1 reference

Transformation of rat embryo fibroblasts by cloned polyoma virus DNA fragments containing only part of the early region

31 March 2020

1 reference

Polyoma large tumor antigen is not required for tumorigenesis mediated by viral DNA.

31 March 2020

1 reference

Coding capacity of a 35 percent fragment of the polyoma virus genome is sufficient to initiate and maintain cellular transformation

31 March 2020

1 reference

The roles of individual polyoma virus early proteins in oncogenic transformation

31 March 2020

1 reference

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines

31 March 2020

1 reference

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

31 March 2020

1 reference

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

31 March 2020

1 reference

Polyoma virus disrupts ARF signaling to p53.

31 March 2020

1 reference

Protein kinase activity associated with the avian sarcoma virus src gene product

31 March 2020

1 reference

An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates

31 March 2020

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Phosphorylation of polyoma T antigens

31 March 2020

1 reference

Protein kinase activity associated with polyoma virus middle T antigen in vitro

31 March 2020

1 reference

Polyoma virus transforming protein associates with the product of the c-src cellular gene

31 March 2020

1 reference

Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

31 March 2020

1 reference

Tyr527 is phosphorylated in pp60c-src: implications for regulation

31 March 2020

1 reference

Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen

31 March 2020

1 reference

Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol

31 March 2020

1 reference

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

31 March 2020

1 reference

Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation

31 March 2020

1 reference

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

31 March 2020

1 reference

An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase

31 March 2020

1 reference

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

31 March 2020

1 reference

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

31 March 2020

1 reference

Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis

31 March 2020

1 reference

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

31 March 2020

1 reference

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

31 March 2020

1 reference

Association between src-kinases and the polyoma virus oncogene middle T-antigen requires PP2A and a specific sequence motif

31 March 2020

1 reference

Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc.

31 March 2020

1 reference

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

31 March 2020

1 reference

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

31 March 2020

1 reference

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

31 March 2020

1 reference

Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1.

31 March 2020

1 reference

Association of polyomavirus middle tumor antigen with 14-3-3 proteins

31 March 2020

1 reference

Host-dependent evolution of three papova viruses

31 March 2020

1 reference

Multiple forms of polyoma virus tumor antigens from infected and transformed cells

31 March 2020

1 reference

7 January 2021

Middle T antigen as primary inducer of full expression of the phenotype of transformation by polyoma virus.

1 reference

7 January 2021

Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase

1 reference

7 January 2021

A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity

1 reference

7 January 2021

Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins

1 reference

7 January 2021

Identifiers

DOI

10.1038/NRC946

1 reference

5 August 2017

1 reference

PubMed ID

12459733