(Q35015406)

5 August 2017

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title

Ibuprofen: pharmacology, efficacy and safety (English)

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5 August 2017

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K D Rainsford

1

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5 August 2017

21 November 2009

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5 August 2017

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5 August 2017

17

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5 August 2017

275-342

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5 August 2017

6

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https://scigraph.springernature.com/pub.10.1007/s10787-009-0016-x

5 August 2017

0 references

cites work

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Stereoselective disposition of ibuprofen enantiomers in human cerebrospinal fluid

21 January 2018

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Single-dose pharmacokinetics of ibuprofen and acetaminophen in febrile children

21 January 2018

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Stereoselective disposition of ibuprofen in patients with compromised renal haemodynamics

21 January 2018

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The effect of glucose and galactose toxicity on myo-inositol transport and metabolism in human skin fibroblasts in culture

21 January 2018

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Ibuprofen kinetics in plasma and synovial fluid of arthritic patients

21 January 2018

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Variability in the stereoselective disposition of ibuprofen in patients with rheumatoid arthritis

21 January 2018

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Efficacy and tolerability of lumiracoxib, a highly selective cyclo-oxygenase-2 (COX2) inhibitor, in the management of pain and osteoarthritis

21 January 2018

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Resolution of inflammation: prostaglandin E2 dissociates nuclear trafficking of individual NF-kappaB subunits (p65, p50) in stimulated rheumatoid synovial fibroblasts.

21 January 2018

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Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study

21 January 2018

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The aspirin-ibuprofen interaction in rheumatoid arthritis

21 January 2018

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Nonsteroidal antiinflammatory drugs and acute renal failure in elderly persons

21 January 2018

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The impact of ibuprofen on the efficacy of antihypertensive treatment with hydrochlorothiazide in elderly persons

21 January 2018

1 reference

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Ibuprofen or acetaminophen for the acute treatment of migraine in children: a double-blind, randomized, placebo-controlled, crossover study.

21 January 2018

1 reference

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A major role for prostacyclin in nitric oxide-induced ocular vasorelaxation in the piglet.

21 January 2018

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Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis

21 January 2018

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The use of COX-2 inhibitors for acute dental pain: A second look

21 January 2018

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Cyclooxygenase-2 modulates afferent arteriolar responses to increases in pressure.

21 January 2018

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The Site of Inversion of R(–)-Ibuprofen: Studies Using Rat In-situ Isolated Perfused Intestine/liver Preparations

21 January 2018

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Do nonsteroidal anti-inflammatory drugs affect blood pressure? A meta-analysis

21 January 2018

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Pharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile children

21 January 2018

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Lack of effect of gender and oral contraceptive steroids on the pharmacokinetics of (R)-ibuprofen in humans

21 January 2018

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The correlation between blood levels of ibuprofen and clinical analgesic response

21 January 2018

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21 January 2018

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Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study

21 January 2018

1 reference

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Effect of ibuprofen on platelet function in normal subjects and hemophiliac patients

21 January 2018

1 reference

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Ibuprofen and paracetamol: relative safety in non-prescription dosages

21 January 2018

1 reference

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Biliary elimination of non-steroidal anti-inflammatory drugs in patients

21 January 2018

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Analgesic dose-response relationship of ibuprofen 50, 100, 200, and 400 mg after surgical removal of third molars: a single-dose, randomized, placebo-controlled, and double-blind study of 304 patients

21 January 2018

1 reference

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The stereoselective disposition of the enantiomers of ibuprofen in blood, blister and synovial fluid

21 January 2018

1 reference

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An evaluation of different ibuprofen preparations in the control of postoperative pain after third molar surgery

21 January 2018

1 reference

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Use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs in high doses increases mortality and risk of reinfarction in patients with prior myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Observations on the gastric mucosa of rheumatic patients before and after ibuprofen administration as studied by the pentagastrin test, endoscopy, and light and electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Ibuprofen, acetaminophen, and placebo treatment of febrile children

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Protein binding of non-steroidal anti-inflammatory drugs in plasma and synovial fluid of arthritic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Renal effects of over-the-counter analgesics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10787-009-0016-X

Risk of serious upper gastrointestinal toxicity with over-the-counter nonaspirin nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

12 December 2020

Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock.

1 reference

12 December 2020

Antipyretic analgesics: nonsteroidal antiinflammatory drugs, selective COX-2 inhibitors, paracetamol and pyrazolinones.

1 reference

12 December 2020

The prevalence of ibuprofen-sensitive asthma in children: a randomized controlled bronchoprovocation challenge study

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of enantiomers of ibuprofen and flurbiprofen after oral administration

1 reference

12 December 2020

Clinical pharmacokinetics of drugs used in juvenile arthritis

1 reference

12 December 2020

Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers

1 reference

12 December 2020

Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells

1 reference

12 December 2020

A case-control study of necrotizing fasciitis during primary varicella

1 reference

12 December 2020

The medical management of chronic arthritis in childhood

1 reference

12 December 2020

30-Day Mortality After Peptic Ulcer Perforation Among Users of Newer Selective Cox-2 Inhibitors and Traditional NSAIDs: A Population-Based Study

1 reference

12 December 2020

NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide.

1 reference

12 December 2020

Effects of acetaminophen and ibuprofen on renal function in the stressed kidney

1 reference

12 December 2020

Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee

1 reference

12 December 2020

Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Kinetic basis for selective inhibition of cyclo-oxygenases

1 reference

12 December 2020

Tubular necrosis after non-steroidal anti-inflammatory agents and acute alcoholic intoxication

1 reference

12 December 2020

Aspirin, ibuprofen, and mortality after myocardial infarction: retrospective cohort study

1 reference

12 December 2020

Peptic ulcer in the very old patients

1 reference

12 December 2020

Single dose oral ibuprofen for acute postoperative pain in adults

1 reference

12 December 2020

Hepatotoxicity of non-narcotic analgesics

1 reference

12 December 2020

Pharmacokinetics of ibuprofen enantiomers in children with cystic fibrosis

1 reference

12 December 2020

Tolerability of ibuprofen, aspirin and paracetamol for the treatment of cold and flu symptoms and sore throat pain

1 reference

12 December 2020

Gastrointestinal tract bleeding associated with naproxen sodium vs ibuprofen

1 reference

12 December 2020

Prophylaxis with acetaminophen or ibuprofen for prevention of local reactions to the fifth diphtheria-tetanus toxoids-acellular pertussis vaccination: a randomized, controlled trial.

1 reference

12 December 2020

Single-dose, placebo-controlled comparative study of ibuprofen and acetaminophen antipyresis in children

1 reference

12 December 2020

Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib

1 reference

12 December 2020

Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis. A prospective observational cohort study

1 reference

12 December 2020

Is there an interaction between the cardiovascular protective effects of low-dose aspirin and ibuprofen?

1 reference

12 December 2020

Tripterine inhibits the expression of adhesion molecules in activated endothelial cells.

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding

1 reference

12 December 2020

Assessment of ibuprofen-associated nephrotoxicity in renal dysfunction

1 reference

12 December 2020

An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial

1 reference

12 December 2020

Drug interactions and consequences of sodium restriction

1 reference

12 December 2020

Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and after study

1 reference

12 December 2020

Cerebrospinal fluid distribution of ibuprofen after intravenous administration in children.

1 reference

12 December 2020

Human pharmacokinetics of ibuprofen enantiomers following different doses and formulations: intestinal chiral inversion.

1 reference

12 December 2020

Renal adaptation to stress: a possible role of endothelin release and prostaglandin modulation in the human subject

1 reference

12 December 2020

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial

1 reference

12 December 2020

Incidence of gastroduodenal ulcers associated with valdecoxib compared with that of ibuprofen and diclofenac in patients with osteoarthritis

1 reference

12 December 2020

Adverse drug interactions involving common prescription and over-the-counter analgesic agents

1 reference

12 December 2020

Pharmacokinetics of the R(-) and S(+) enantiomers of ibuprofen in the serum and synovial fluid of arthritis patients

1 reference

12 December 2020

Cutaneous reactions to drugs. An analysis of spontaneous reports in four Italian regions

1 reference

12 December 2020

Discovery, mechanisms of action and safety of ibuprofen

1 reference

12 December 2020

An evidence-based approach to the gastrointestinal safety profile of COX-2-selective anti-inflammatories

1 reference

12 December 2020

Pharmacokinetics and bioinversion of ibuprofen enantiomers in humans

1 reference

12 December 2020

Evaluation of trismus, bite force, and pressure algometry after third molar surgery: a placebo-controlled study of ibuprofen

1 reference

12 December 2020

Non-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use

1 reference

12 December 2020

Development of new pain management strategies.

1 reference

12 December 2020

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study

1 reference

12 December 2020

Comparative efficacy and tolerance of ibuprofen syrup and acetaminophen syrup in children with pyrexia associated with infectious diseases and treated with antibiotics

1 reference

12 December 2020

Clinical pharmacology of lumiracoxib, a second-generation cyclooxygenase 2 selective inhibitor

1 reference

12 December 2020

Clinical consequences of cytochrome P450 2C9 polymorphisms

1 reference

12 December 2020

Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2.

1 reference

12 December 2020

[Ibuprofen in childhood: evidence-based review of efficacy and safety].

1 reference

12 December 2020

Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2.

1 reference

12 December 2020

Epidemiology of adverse drug reactions in the elderly by drug class

1 reference

12 December 2020

Role of cyclooxygenase-2 in the prolonged regulation of renal function

1 reference

12 December 2020

Antipyretic drugs for children

1 reference

12 December 2020

Risk factors for adverse events in analgesic drug users: results from the PAIN study

1 reference

12 December 2020

Serious skin reactions and selective COX-2 inhibitors: a case series from prescription-event monitoring in England

1 reference

12 December 2020

Stereoselective pharmacokinetics of ibuprofen and its lysinate from suppositories in rabbits

1 reference

12 December 2020

Antirheumatic drug therapy in the elderly: a case of failure to identify the correct issues?

1 reference

12 December 2020

Mechanisms of the nephrotoxicity of non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Randomized controlled noninferiority trial to compare extended release acetaminophen and ibuprofen for the treatment of ankle sprains

1 reference

12 December 2020

Invasive group A streptococcal infection and nonsteroidal antiinflammatory drug use among children with primary varicella

1 reference

12 December 2020

A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure

1 reference

12 December 2020

Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use.

1 reference

12 December 2020

Challenge-based clinical patterns of 223 Spanish patients with nonsteroidal anti-inflammatory-drug-induced-reactions

1 reference

12 December 2020

Effect of absorption rate on pharmacokinetics of ibuprofen in relation to chiral inversion in humans

1 reference

12 December 2020

Appropriate use of nonprescription analgesics in pediatric patients

1 reference

12 December 2020

The IPSO study: ibuprofen, paracetamol study in osteoarthritis. A randomised comparative clinical study comparing the efficacy and safety of ibuprofen and paracetamol analgesic treatment of osteoarthritis of the knee or hip.

1 reference

12 December 2020

A comparative endoscopic evaluation of the damaging effects of nonsteroidal anti-inflammatory agents on the gastric and duodenal mucosa

1 reference

12 December 2020

OTC analgesics and drug interactions: clinical implications

1 reference

12 December 2020

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study

1 reference

12 December 2020

Evaluation of the efficacy and dose-response relationship of dexibuprofen (S(+)-ibuprofen) in patients with osteoarthritis of the hip and comparison with racemic ibuprofen using the WOMAC osteoarthritis index.

1 reference

12 December 2020

Necrotizing soft tissue infections reported with nonsteroidal antiinflammatory drugs.

1 reference

12 December 2020

Arthritis medicines and cardiovascular events--"house of coxibs".

1 reference

12 December 2020

Clinical pharmacology of predisintegrated ibuprofen 800 mg tablets: an endoscopic and pharmacokinetic study

1 reference

12 December 2020

The balance between severe cardiovascular and gastrointestinal events among users of selective and non-selective non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Systematic review: the lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Apoptosis in ibuprofen-induced Stevens-Johnson syndrome.

1 reference

12 December 2020

Absorption kinetics of rectally and orally administered ibuprofen

1 reference

12 December 2020

Ibuprofen liquigel for oral surgery pain

1 reference

12 December 2020

Efficacy and safety of over-the-counter analgesics in the treatment of common cold and flu

1 reference

12 December 2020

Dose-response in direct comparisons of different doses of aspirin, ibuprofen and paracetamol (acetaminophen) in analgesic studies

1 reference

12 December 2020

A controlled study comparing the effects of nabumetone, ibuprofen, and ibuprofen plus misoprostol on the upper gastrointestinal tract mucosa.

1 reference

12 December 2020

Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports

1 reference

12 December 2020

The stereoselective uptake of ibuprofen enantiomers into adipose tissue

1 reference

12 December 2020

A randomized trial of the efficacy and tolerability of the COX-2 inhibitor rofecoxib vs ibuprofen in patients with osteoarthritis. Rofecoxib/Ibuprofen Comparator Study Group

1 reference

12 December 2020

Toxicity of antirheumatic medications in children with juvenile arthritis

1 reference

12 December 2020

Renal function after short-term ibuprofen use in infants and children

1 reference

12 December 2020

Nonsteroidal Antiinflammatory Drugs and Acute Myocardial Infarction in Patients with No Major Risk Factors

1 reference

12 December 2020

Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis

1 reference

12 December 2020

Clinical pharmacokinetics in infants and children. A reappraisal

1 reference

12 December 2020

Implications of NSAID therapy in elderly patients

1 reference

12 December 2020

Ibuprofen and asthma in paediatric populations: clinical concern or clinical reality?

1 reference

12 December 2020

Dosage of salicylates for children with juvenile rheumatoid arthritis. A prospective clinical trial with three different preparations of acetylsalicylic acid

1 reference

12 December 2020

Pharmacokinetics of ibuprofen

1 reference

12 December 2020

Hepatic drug metabolism in cystic fibrosis: recent developments and future directions

1 reference

12 December 2020

A randomized trial to determine the change in alanine aminotransferase during 10 days of paracetamol (acetaminophen) administration in subjects who consume moderate amounts of alcohol.

1 reference

12 December 2020

Ibuprofen in the management of Still's disease

1 reference

12 December 2020

Involvement of peripheral cyclooxygenase-1 and cyclooxygenase-2 in inflammatory pain

1 reference

12 December 2020

Endoscopic evaluation of the effect of ketoprofen, ibuprofen and aspirin on the gastroduodenal mucosa

1 reference

12 December 2020

Risk of skin reactions when using ibuprofen-based medicines

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drug-associated upper gastrointestinal lesions in rheumatoid arthritis patients. Relationships to gastric histology, Helicobacter pylori infection, and other risk factors for peptic ulcer.

1 reference

12 December 2020

An evaluation of preoperative ibuprofen for treatment of pain associated with orthodontic separator placement

1 reference

12 December 2020

Symptomatic treatment of migraine in children: a systematic review of medication trials

1 reference

12 December 2020

[Protective effects of ranitidine in ibuprofen gastroduodenopathy. An endoscopic controlled double blind study]

1 reference

12 December 2020

Effects of the antifungals voriconazole and fluconazole on the pharmacokinetics of s-(+)- and R-(-)-Ibuprofen

1 reference

12 December 2020

Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review

1 reference

12 December 2020

The safety profile of nonprescription ibuprofen in multiple-dose use: a meta-analysis

1 reference

12 December 2020

Asthma morbidity after the short-term use of ibuprofen in children

1 reference

12 December 2020

When a randomised controlled trial is needed to assess drug safety. The case of paediatric ibuprofen

1 reference

12 December 2020

Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and Ibuprofen in the treatment of osteoarthritis of the knee

1 reference

12 December 2020

Down-regulation of nitric oxide production by ibuprofen in human volunteers.

1 reference

12 December 2020

Inhibition of cyclooxygenase-1 and -2 by R(-)- and S(+)-ibuprofen

1 reference

12 December 2020

Risk of serious NSAID-related gastrointestinal events during long-term exposure: a systematic review

1 reference

12 December 2020

Cyclooxygenase inhibitors and the antiplatelet effects of aspirin

1 reference

12 December 2020

The safety of ibuprofen suspension in children

1 reference

12 December 2020

Pharmacokinetics of rectal drug administration, Part II. Clinical applications of peripherally acting drugs, and conclusions

1 reference

12 December 2020

Effect of ibuprofen in patients with severe sepsis: a randomized, double-blind, multicenter study. The Ibuprofen Study Group

1 reference

12 December 2020

Morning versus evening dosing of ibuprofen using conventional and time-controlled release formulations

1 reference

12 December 2020

Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases

1 reference

12 December 2020

Cyclooxygenase-independent actions of cyclooxygenase inhibitors

1 reference

12 December 2020

Safety profile of ibuprofen suspension in young children

1 reference

12 December 2020

Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice

1 reference

12 December 2020

Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury

1 reference

12 December 2020

Intrasubject variability in bioequivalence studies illustrated by the example of ibuprofen

1 reference

12 December 2020

Enhanced analgesia and suppression of plasma beta-endorphin by the S(+)-isomer of ibuprofen.

1 reference

12 December 2020

Pharmacokinetics of ibuprofen in febrile children

1 reference

12 December 2020

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

1 reference

12 December 2020

A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis

1 reference

12 December 2020

Preoperative acetaminophen vs ibuprofen for control of pain after orthodontic separator placement.

1 reference

12 December 2020

Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain

1 reference

12 December 2020

Hypothermia in a child secondary to ibuprofen

1 reference

12 December 2020

Review article: drug hepatotoxicity

1 reference

12 December 2020

Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison

1 reference

12 December 2020

Cardiovascular effects of the selective cyclooxygenase-2 inhibitors

1 reference

12 December 2020

Pharmacokinetics of non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen

1 reference

12 December 2020

Autoradiographic and biochemical observations on the distribution of non-steroid anti-inflammatory drugs

1 reference

12 December 2020

COX-2 controversy: where are we and where do we go from here?

1 reference

12 December 2020

NSAIDs-induced gastrointestinal damage. Review

1 reference

12 December 2020

Age and renal prostaglandin inhibition during exercise and heat stress

1 reference

12 December 2020

Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat

1 reference

12 December 2020

Fracture risk associated with use of nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, and acetaminophen and the effects of rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Determinants of the short-term gastric damage caused by NSAIDs in man.

1 reference

12 December 2020

Cardiovascular risk profile of antirheumatic agents in patients with osteoarthritis and rheumatoid arthritis

1 reference

12 December 2020

Ibuprofen: effect on inducible nitric oxide synthase.

1 reference

12 December 2020

A quantitative circular dichroic investigation of the binding of the enantiomers of ibuprofen and naproxen to human serum albumin

1 reference

12 December 2020

Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition

1 reference

12 December 2020

Concentrations of ibuprofen in serum and synovial fluid from patients with arthritis [proceedings]

1 reference

12 December 2020

Effect of high-dose ibuprofen in patients with cystic fibrosis.

1 reference

12 December 2020

Pain-mediated altered absorption and metabolism of ibuprofen: an explanation for decreased serum enantiomer concentration after dental surgery

1 reference

12 December 2020

Are selective COX 2 inhibitors superior to traditional non steroidal anti-inflammatory drugs?

1 reference

12 December 2020

Acute treatment of paediatric migraine: a meta-analysis of efficacy.

1 reference

12 December 2020

Parents' fear regarding fever and febrile seizures

1 reference

12 December 2020

Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function

1 reference

12 December 2020

Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports

1 reference

12 December 2020

Potential for drug-drug interactions in patients taking analgesics for mild-to-moderate pain and low-dose aspirin for cardioprotection

1 reference

12 December 2020

Cytokine profile in human skin in response to experimental inflammation, noxious stimulation, and administration of a COX-inhibitor: a microdialysis study

1 reference

12 December 2020

Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin?

1 reference

12 December 2020

Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Gastrointestinal complications of prescription and over-the-counter nonsteroidal anti-inflammatory drugs: a view from the ARAMIS database. Arthritis, Rheumatism, and Aging Medical Information System.

1 reference

12 December 2020

Ibuprofen suspension in the treatment of juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group

1 reference

12 December 2020

Ibuprofen: a journey from prescription to over-the-counter use

1 reference

12 December 2020

Paracetamol (acetaminophen) pack size restrictions and poisoning severity: time trends in enquiries to a UK poisons centre.

1 reference

12 December 2020

Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal antiinflammatory drugs

1 reference

12 December 2020

Lumiracoxib in the management of osteoarthritis and acute pain

1 reference

12 December 2020

Comparing efficacy and tolerability of ibuprofen and paracetamol in fever

1 reference

12 December 2020

Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations

1 reference

12 December 2020

Efficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis

1 reference

12 December 2020

Ibuprofen and cardiovascular safety: where do we stand?

1 reference

12 December 2020

Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis

1 reference

12 December 2020

A multicentre, long-term evaluation of the safety and efficacy of ibuprofen syrup in children with juvenile chronic arthritis

1 reference

12 December 2020

Individual patient meta-analysis of single-dose rofecoxib in postoperative pain

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene

1 reference

12 December 2020

The relationship between the pharmacokinetics of ibuprofen enantiomers and the dose of racemic ibuprofen in humans

1 reference

12 December 2020

Upper gastrointestinal adverse drug reactions and cyclo-oxygenase-2 inhibitors (celecoxib and rofecoxib): a case/non-case study from the French Pharmacovigilance Database

1 reference

12 December 2020

Inhibition of cytokine production and adhesion molecule expression by ibuprofen is without effect on transendothelial migration of monocytes

1 reference

12 December 2020

Equivalent antipyretic activity of ibuprofen and paracetamol in febrile children

1 reference

12 December 2020

Allergy and intolerance to nonsteroidal anti-inflammatory agents

1 reference

12 December 2020

Perioperative pharmacokinetics of ibuprofen enantiomers after rectal administration

1 reference

12 December 2020

Effect of dosage form on stereoisomeric inversion of ibuprofen in volunteers

1 reference

12 December 2020

Therapeutically relevant differences in the pharmacokinetical and pharmaceutical behavior of ibuprofen lysinate as compared to ibuprofen acid

1 reference

12 December 2020

Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma

1 reference

12 December 2020

Myth: parenteral ketorolac provides more effective analgesia than oral ibuprofen.

1 reference

12 December 2020

Comparison of Multidose Ibuprofen and Acetaminophen Therapy in Febrile Children

1 reference

12 December 2020

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

1 reference

12 December 2020

Use of ibuprofen in paediatric populations

1 reference

12 December 2020

Randomized, controlled trial of ibuprofen syrup administered during febrile illnesses to prevent febrile seizure recurrences

1 reference

12 December 2020

Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Drug-induced liver disease

1 reference

12 December 2020

Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients

1 reference

12 December 2020

Cardiovascular safety of lumiracoxib: a meta-analysis of all randomized controlled trials > or =1 week and up to 1 year in duration of patients with osteoarthritis and rheumatoid arthritis

1 reference

12 December 2020

The use of non-steroidal anti-inflammatory drugs in paediatric rheumatic diseases

1 reference

12 December 2020

The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents

1 reference

12 December 2020

Randomized, double-blind, multicenter, controlled trial of ibuprofen versus acetaminophen (paracetamol) and placebo for treatment of symptoms of tonsillitis and pharyngitis in children

1 reference

12 December 2020

Effects of chronic NSAIDs on gastric mucosal injury related to mucosal prostanoids, and plasma drug concentrations in human volunteers

1 reference

12 December 2020

Effects of ibuprofen on plasma endothelin levels and some vital parameters during endotoxin shock in rabbits

1 reference

12 December 2020

Optimal assessment of gastrointestinal side effects induced by non-steroidal anti-inflammatory drugs. Endoscopic lesions, faecal blood loss, and symptoms not necessarily correlated, as observed after naproxen and oxindanac in healthy volunteers.

1 reference

12 December 2020

Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population

1 reference

12 December 2020

What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs

1 reference

12 December 2020

Population pharmacokinetics of high dose ibuprofen in cystic fibrosis

1 reference

12 December 2020

The effects of nonselective non-aspirin non-steroidal anti-inflammatory medications on the risk of nonfatal myocardial infarction and their interaction with aspirin

1 reference

12 December 2020

Cyclooxygenase-1 and Cyclooxygenase-2 Selectivity of Widely Used Nonsteroidal Anti-Inflammatory Drugs

1 reference

12 December 2020

A dose ranging study of ibuprofen suspension as an antipyretic

1 reference

12 December 2020

Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction

1 reference

12 December 2020

Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly

1 reference

12 December 2020

An endoscopic comparison of the effects of etodolac, indomethacin, ibuprofen, naproxen, and placebo on the gastrointestinal mucosa

1 reference

12 December 2020

Experimental pain in healthy human subjects: gender differences in nociception and in response to ibuprofen.

1 reference

12 December 2020

Spinal prostaglandin formation and pain perception following thoracotomy: a role for cyclooxygenase-2.

1 reference

12 December 2020

Acetaminophen for osteoarthritis

1 reference

12 December 2020

Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects

1 reference

12 December 2020

Ibuprofen in the management of osteoarthrosis of the hip

1 reference

12 December 2020

Pharmacokinetics of common analgesics, anti-inflammatories and antipyretics in children

1 reference

12 December 2020

Clinical efficacy and differential inhibition of menstrual fluid prostaglandin F2alpha in a randomized, double-blind, crossover treatment with placebo, acetaminophen, and ibuprofen in primary dysmenorrhea

1 reference

12 December 2020

Efficacy of ibuprofen in pediatric patients with fever

1 reference

12 December 2020

The effect of preemptive and/or postoperative ibuprofen therapy for orthodontic pain

1 reference

12 December 2020

A general overview of the use of ibuprofen in paediatrics

1 reference

12 December 2020

Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient

1 reference

12 December 2020

Treatment of knee osteoarthritis: relationship of clinical features of joint inflammation to the response to a nonsteroidal antiinflammatory drug or pure analgesic

1 reference

12 December 2020

Selecting nonprescription analgesics.

1 reference

12 December 2020

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

1 reference

12 December 2020

Upper gastrointestinal bleeding associated with the use of NSAIDs: newer versus older agents.

1 reference

12 December 2020

Risk of acute liver injury associated with the use of drugs: a multicentre population survey

1 reference

12 December 2020

Cohort study of hepatotoxicity associated with nimesulide and other non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Developmental aspects of human hepatic drug glucuronidation in young children and adults

1 reference

12 December 2020

The case for an adverse interaction between aspirin and non-steroidal anti-inflammatory drugs: is it time to believe the hype?

1 reference

12 December 2020

A real time quantitative PCR analysis and correlation of COX-1 and COX-2 enzymes in inflamed dental pulps following administration of three different NSAIDs

1 reference

12 December 2020

COX-dependent mechanisms involved in the antinociceptive action of NSAIDs at central and peripheral sites

1 reference

12 December 2020

French guidelines for the diagnosis and management of migraine in adults and children

1 reference

12 December 2020

A comparative study of two dosage levels of ibuprofen syrup in children with pyrexia

1 reference

12 December 2020

Ibuprofen use in children: a benefit or a risk?

1 reference

12 December 2020

Tolerance and pharmacology of ibuprofen

1 reference

12 December 2020

Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions

1 reference

12 December 2020

Paracetamol and ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial.

1 reference

12 December 2020

Stereoselectivity and enantiomer-enantiomer interactions in the binding of ibuprofen to human serum albumin.

1 reference

12 December 2020

Ibuprofen as a pre-emptive analgesic is as effective as rofecoxib for mandibular third molar surgery

1 reference

12 December 2020

Ibuprofen and gastrointestinal safety: a dose-duration-dependent phenomenon

1 reference

12 December 2020

Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations

1 reference

12 December 2020

Role of Cyclooxygenase-2-Derived Metabolites and NO in Renal Response to Bradykinin

1 reference

12 December 2020

Temperature, age, and recurrence of febrile seizure

1 reference

12 December 2020

The murky waters of the coxibs: a review of the current state of play

1 reference

12 December 2020

Introduction - The coxib controversies

1 reference

12 December 2020

A randomized trial measuring fecal blood loss after treatment with rofecoxib, ibuprofen, or placebo in healthy subjects

1 reference

12 December 2020

Review of the analgesic efficacy of ibuprofen

1 reference

12 December 2020

Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.

1 reference

12 December 2020

The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1.

1 reference

12 December 2020

Migraine and headache in childhood

1 reference

12 December 2020

Renovascular effects of nonprescription ibuprofen in elderly hypertensive patients with mild renal impairment

1 reference

12 December 2020

Comparison of the efficacy and safety of nonprescription doses of naproxen and naproxen sodium with ibuprofen, acetaminophen, and placebo in the treatment of primary dysmenorrhea: a pooled analysis of five studies

1 reference

12 December 2020

The pharmacokinetics of ibuprofen suspension, chewable tablets, and tablets in children with cystic fibrosis.

1 reference

12 December 2020

Comparison of rofecoxib, celecoxib, and naproxen on renal function in elderly subjects receiving a normal-salt diet

1 reference

12 December 2020

Over the counter non-steroidal anti-inflammatory drugs and risk of gastrointestinal bleeding

1 reference

12 December 2020

Ibuprofen in the treatment of rheumatoid arthritis and osteo-arthritis

1 reference

12 December 2020

Antipyretic treatment in young children with fever: acetaminophen, ibuprofen, or both alternating in a randomized, double-blind study

1 reference

12 December 2020

Hypersensitivity to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)

1 reference

12 December 2020

Measurement of clinical response to anti-inflammatory drug therapy in rheumatoid arthritis

1 reference

12 December 2020

Pharmacologic treatment of acute migraine attack in children

1 reference

12 December 2020

Use of nonsteroidal anti-inflammatory drugs in infants. A survey of members of the Association of Paediatric Anaesthetists of Great Britain and Ireland

1 reference

12 December 2020

The relative toxicity of nonsteroidal antiinflammatory drugs

1 reference

12 December 2020

Statistical meta-analysis of multicenter clinical studies of ibuprofen with regard to cohort size

1 reference

12 December 2020

Upregulation of ICAM-1 expression in bronchial epithelial cells by airway secretions in bronchiectasis.

1 reference

12 December 2020

Pharmacokinetics of S(+)- and R(-)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis.

1 reference

12 December 2020

Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells

1 reference

12 December 2020

Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association

1 reference

12 December 2020

Antipyretic efficacy of ibuprofen vs acetaminophen

1 reference

12 December 2020

Dose-response of minor analgesics in acute pain

1 reference

12 December 2020

Gastrointestinal complications of over-the-counter nonsteroidal antiinflammatory drugs

1 reference

12 December 2020

Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells

1 reference

12 December 2020

Risks and benefits of nonsteroidal anti-inflammatory drugs in children: a comparison with paracetamol

1 reference

12 December 2020

Management of chronic musculoskeletal pain in the elderly: opinions on oral medication use.

1 reference

12 December 2020

Risk of hospitalization for angio-oedema among users of newer COX-2 selective inhibitors and other nonsteroidal anti-inflammatory drugs

1 reference

12 December 2020

Early presentation with angioedema and urticaria in cross-reactive hypersensitivity to nonsteroidal antiinflammatory drugs among young, Asian, atopic children

1 reference

12 December 2020

[Focus on the safety of ibuprofen at the analgesic-antipyretic dose]

1 reference

12 December 2020

Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen

1 reference

12 December 2020

A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children

1 reference

12 December 2020

Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs

1 reference

12 December 2020

Renal targeting of a non-steroidal anti-inflammatory drug: effects on renal prostaglandin synthesis in the rat

1 reference

12 December 2020

Comparative evaluation of antipyretic activity of ibuprofen and aspirin in children with pyrexia of varied aetiology

1 reference

12 December 2020

Use of nonsteroidal anti-inflammatory drugs and risk of fractures

1 reference

12 December 2020

Review of ibuprofen for osteoarthritis.

1 reference

12 December 2020

Failing the public health--rofecoxib, Merck, and the FDA.

1 reference

12 December 2020

Efficacy of low-dose ibuprofen in acute migraine treatment: systematic review and meta-analysis

1 reference

12 December 2020

Ibuprofen as an over-the-counter drug: is there a risk for renal injury?

1 reference

12 December 2020

Perioperative acute renal failure associated with preoperative intake of ibuprofen

1 reference

12 December 2020

Inhibition of the renin-angiotensin system upregulates cyclooxygenase-2 expression in the macula densa

1 reference

12 December 2020

Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.

1 reference

12 December 2020

A randomized clinical trial: should the child with transient synovitis of the hip be treated with nonsteroidal anti-inflammatory drugs?

1 reference

12 December 2020

Pharmacokinetic-Pharmacodynamic Modelling of the antipyretic effect of two oral formulations of ibuprofen

1 reference

12 December 2020

Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals

1 reference

12 December 2020

Over-the-counter analgesics and antipyretics: a critical assessment

1 reference

12 December 2020

Emergency department visits for acetaminophen overdose: a Canadian population-based epidemiologic study (1997-2002)

1 reference

12 December 2020

Potential benefits of ibuprofen in the treatment of viral respiratory infections

1 reference

12 December 2020

Subgroup analyses to determine cardiovascular risk associated with nonsteroidal antiinflammatory drugs and coxibs in specific patient groups.

1 reference

12 December 2020

Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells

1 reference

12 December 2020

Best evidence topic report. Non-steroidal anti-inflammatory drugs and exacerbations of asthma in children.

1 reference

12 December 2020

Acute renal failure after treatment with non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Epidemiology of nonsteroidal anti-inflammatory drug-associated gastrointestinal injury

1 reference

12 December 2020

Assessing the effects of non-steroidal anti-inflammatory drugs on antihypertensive drug therapy using post-marketing surveillance database

1 reference

12 December 2020

Cyclooxygenase inhibition reveals synergistic action of vasoconstrictors on mesangial cell growth

1 reference

12 December 2020

[Severe renal adverse events with arylcarboxylic non-steroidal anti-inflammatory drugs: results of a eight-year French national survey]

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care

1 reference

12 December 2020

Is any one analgesic superior for episodic tension-type headache?

1 reference

12 December 2020

Fever phobia revisited: have parental misconceptions about fever changed in 20 years?

1 reference

12 December 2020

Ibuprofen elevates immunoreactive beta-endorphin levels in humans during surgical stress.

1 reference

12 December 2020

Over-the-counter oral nonsteroidal anti-inflammatory drugs: a pharmacoepidemiologic study in southern Italy

1 reference

12 December 2020

Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells

1 reference

12 December 2020

Analgesic efficacy of celecoxib in postoperative oral surgery pain: a single-dose, two-center, randomized, double-blind, active- and placebo-controlled study

1 reference

12 December 2020

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial

1 reference

12 December 2020

Characterization of the protein binding of chiral drugs by high-performance affinity chromatography. Interactions of R- and S-ibuprofen with human serum albumin

1 reference

12 December 2020

Effect of age on ibuprofen pharmacokinetics and antipyretic response

1 reference

12 December 2020

A search for sex differences in response to analgesia

1 reference

12 December 2020

Antipyretic activity of ibuprofen and paracetamol in children with pyrexia

1 reference

12 December 2020

Ibuprofen administration attenuates serum TNF-alpha levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation

1 reference

12 December 2020

Pain control: non-steroidal anti-inflammatory agents.

1 reference

12 December 2020

Evaluation of risk profiles for gastrointestinal and cardiovascular adverse effects in nonselective NSAID and COX-2 inhibitor users: a cohort study using pharmacy dispensing data in The Netherlands.

1 reference

12 December 2020

Allergic and pseudoallergic reactions to analgesics, antipyretics and non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

The safety of acetaminophen and ibuprofen among children younger than two years old.

1 reference

12 December 2020

Ibuprofen interferes with the efficacy of antihypertensive drugs. A randomized, double-blind, placebo-controlled trial of ibuprofen compared with acetaminophen

1 reference

12 December 2020

Safety profile of over-the-counter naproxen sodium

1 reference

12 December 2020

Nonsteroidal antiinflammatory drugs after acute myocardial infarction

1 reference

12 December 2020

Gastrointestinal safety and tolerance of ibuprofen at maximum over-the-counter dose

1 reference

12 December 2020

COX2 selective NSAIDs and renal function: gain without pain?

1 reference

12 December 2020

Defining the problem of treating the patient with hypertension and arthritis pain

1 reference

12 December 2020

Osteoarthritis: symptoms, signs and source of pain

1 reference

12 December 2020

Oral analgesics for acute nonspecific pain

1 reference

12 December 2020

Severity of knee pain does not predict a better response to an antiinflammatory dose of ibuprofen than to analgesic therapy in patients with osteoarthritis

1 reference

12 December 2020

Evaluation of ibuprofen versus aspirin and paracetamol on efficacy and comfort in children with fever

1 reference

12 December 2020

Isolation and characterization of major phase I and II metabolites of ibuprofen

1 reference

12 December 2020

Genetic and molecular factors in drug-induced liver injury: a review.

1 reference

12 December 2020

A double-blind comparison of ibuprofen and paracetamol in juvenile pyrexia

1 reference

12 December 2020

Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers

1 reference

12 December 2020

Stereoselective metabolism of ibuprofen in humans: administration of R-, S- and racemic ibuprofen

1 reference

12 December 2020

A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma

1 reference

12 December 2020

Reversible membranous nephropathy associated with the use of nonsteroidal anti-inflammatory drugs

1 reference

12 December 2020

COX-2 inhibitors--lessons in drug safety

1 reference

12 December 2020

Ibuprofen plus codeine, ibuprofen, and placebo in a single- and multidose cross-over comparison for coxarthrosis pain

1 reference

12 December 2020

Modulation of nitric oxide synthase activity by ibuprofen

1 reference

12 December 2020

Ibuprofen in children with cystic fibrosis: pharmacokinetics and adverse effects

1 reference

12 December 2020

Parents' attitudes towards childhood fever. A cross-sectional survey in the Lyon metropolitan area (202 cases)

1 reference

12 December 2020

The effects of ibuprofen, indomethacin, aspirin, naproxen, and placebo on the gastric mucosa of normal volunteers: a gastroscopic and photographic study

1 reference

12 December 2020

Interspecies differences in renal localization of cyclooxygenase isoforms: implications in nonsteroidal antiinflammatory drug-related nephrotoxicity

1 reference

12 December 2020

Ibuprofen-induced meningitis in mixed connective tissue disease

1 reference

12 December 2020

CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells.

1 reference

12 December 2020

Pharmacokinetics of ibuprofen enantiomers in humans following oral administration of tablets with different absorption rates

1 reference

12 December 2020

Comparative effects of nabumetone, sulindac, and ibuprofen on renal function.

1 reference

12 December 2020

Risks and benefits of COX-2 inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study

1 reference

12 December 2020

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

1 reference

12 December 2020

Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis

1 reference

12 December 2020

Epidemiology overview of gastrointestinal and renal toxicity of NSAIDs

1 reference

12 December 2020

Ibuprofen in the treatment of postoperative pain in small children. A randomized double-blind-placebo controlled parallel group study

1 reference

12 December 2020

Postextraction pain relief in children: a clinical trial of liquid analgesics

1 reference

12 December 2020

Antioxidant activity and inhibition of human neutrophil oxidative burst mediated by arylpropionic acid non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

The ever-emerging anti-inflammatories. Have there been any real advances?

1 reference

12 December 2020

A randomized clinical trial comparing the efficacy of ibuprofen and paracetamol in the control of orthodontic pain.

1 reference

12 December 2020

Ibuprofen levels in serum and synovial fluid

1 reference

12 December 2020

Recent FDA warning of the concomitant use of aspirin and ibuprofen and the effects on platelet aggregation

1 reference

12 December 2020

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat

1 reference

12 December 2020

Taurine conjugation of ibuprofen in humans and in rat liver in vitro. Relationship to metabolic chiral inversion

1 reference

12 December 2020

A single-blind parallel group study investigating the antipyretic properties of ibuprofen syrup versus acetylsalicylic acid syrup in febrile children

1 reference

12 December 2020

10.1007/S10787-009-0016-X

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

19949916