(Q35015948)

5 August 2017

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title

Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51. (English)

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5 August 2017

Natasa Debeljak

1

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5 August 2017

Martina Fink

series ordinal

2

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5 August 2017

Damjana Rozman

series ordinal

3

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5 August 2017

language of work or name

English

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publication date

1 January 2003

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Archives of Biochemistry and Biophysics

5 August 2017

number of pages

13

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based on heuristic

inferred from page(s)

published in

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5 August 2017

volume

409

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5 August 2017

issue

1

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5 August 2017

page(s)

159-171

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Cytochrome P450 and the individuality of species

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Sterol 14-demethylase P450 (CYP51) provides a breakthrough for the discussion on the evolution of cytochrome P450 gene superfamily

7 January 2021

1 reference

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Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: II. Evolutionary analysis of protein and gene structures

7 January 2021

1 reference

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Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species

7 January 2021

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Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals

7 January 2021

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CYP51-like gene of Mycobacterium tuberculosis actually encodes a P450 similar to eukaryotic CYP51

7 January 2021

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Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis

7 January 2021

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A sterol biosynthetic pathway in Mycobacterium.

7 January 2021

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Chemical structure of sterols that activate oocyte meiosis.

7 January 2021

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Characterization of the mouse lanosterol 14alpha-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family

7 January 2021

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Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana.

7 January 2021

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The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

7 January 2021

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The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family

7 January 2021

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Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes

7 January 2021

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Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: I. Structural analyses of the gene and multiple sizes of mRNA

7 January 2021

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Structure of the pig sterol 14alpha-demethylase (CYP51) gene and its expression in the testis and other tissues

7 January 2021

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Elevated Expression of Lanosterol 14α-Demethylase (CYP51) and the Synthesis of Oocyte Meiosis-Activating Sterols in Postmeiotic Germ Cells of Male Rats1

7 January 2021

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Processed pseudogenes: characteristics and evolution

7 January 2021

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CpG islands in chromatin organization and gene expression

7 January 2021

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A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).

7 January 2021

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Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis

7 January 2021

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LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.

7 January 2021

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Specificity in cholesterol regulation of gene expression by coevolution of sterol regulatory DNA element and its binding protein

7 January 2021

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

7 January 2021

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

7 January 2021

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Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action

7 January 2021

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Gonadotropin-dependent expression of sterol 14-demethylase P450 (CYP51) in rat ovaries and its contribution to the production of a meiosis-activating steroid

7 January 2021

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Insulin is the essential factor maintaining the constitutive expression of hepatic sterol 14-demethylase P450 (CYP51)

7 January 2021

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Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription

7 January 2021

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Dual role of signaling pathways leading to Ca(2+) and cyclic AMP elevation in host cell invasion by Trypanosoma cruzi

7 January 2021

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Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells

7 January 2021

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The luteinizing hormone receptor

7 January 2021

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Transcriptional checkpoints determining the fate of male germ cells

7 January 2021

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CBP-independent activation of CREM and CREB by the LIM-only protein ACT

7 January 2021

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A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM

7 January 2021

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Occurrence of a P450 showing high homology to yeast lanosterol 14-demethylase (P450(14DM)) in the rat liver

7 January 2021

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Lanosterol 14-demethylase activity expressed in rat brain microsomes.

7 January 2021

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Sterol 14-demethylase P450 activity expressed in rat gonads: contribution to the formation of mammalian meiosis-activating sterol.

7 January 2021

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The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450).

7 January 2021

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Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

7 January 2021

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Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents.

7 January 2021

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Generation of a complete, soluble, and catalytically active sterol 14 alpha-demethylase-reductase complex.

7 January 2021

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Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol.

7 January 2021

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Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis

7 January 2021

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Localisation of lanosterol 14alpha-demethylase in round and elongated spermatids of the mouse testis: an immunoelectron microscopic and stereological study.

7 January 2021

1 reference

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The Golgi apparatus segregates from the lysosomal/acrosomal vesicle during rhesus spermiogenesis: structural alterations

7 January 2021

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Mammalian sperm acrosome: formation, contents, and function

7 January 2021

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Role of meiosis-activating sterols in rat oocyte maturation: effects of specific inhibitors and changes in the expression of lanosterol 14alpha-demethylase during the preovulatory period

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Activation of meiotic maturation in rat oocytes after treatment with follicular fluid meiosis-activating sterol in vitro and ex vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Content of meiosis activating sterols in equine follicular fluids: correlation to follicular size and dominance

7 January 2021

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Progestins block cholesterol synthesis to produce meiosis-activating sterols

7 January 2021

1 reference

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Cumulus cells secrete a meiosis-inducing substance by stimulation with forskolin and dibutyric cyclic adenosine monophosphate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Meiosis-activating sterol-mediated resumption of meiosis in mouse oocytes in vitro is influenced by protein synthesis inhibition and cholera toxin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Autoradiographic localization of specific binding of meiosis-activating sterol to cumulus-oocyte complexes from marmoset, cow, and mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Meiosis-activating sterol and the maturation of isolated mouse oocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Effects of ketoconazole on ovulatory changes in the rat: implications on the role of a meiosis-activating sterol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Gonadotropin-induced resumption of oocyte meiosis and meiosis-activating sterols.

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0003-9861(02)00418-6

1 reference

5 August 2017

1 reference