(Q35022609)

5 August 2017

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title

Fractalkine (CX3CL1) and brain inflammation: Implications for HIV-1-associated dementia (English)

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5 August 2017

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R Cotter

1

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5 August 2017

C Williams

2

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5 August 2017

L Ryan

3

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5 August 2017

David Erichsen

4

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5 August 2017

A Lopez

5

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5 August 2017

H Peng

6

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5 August 2017

J Zheng

7

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5 August 2017

language of work or name

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1 December 2002

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5 August 2017

Journal of NeuroVirology

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5 August 2017

8

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5 August 2017

6

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5 August 2017

585-598

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https://scigraph.springernature.com/pub.10.1080/13550280290100950

5 August 2017

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The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement

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Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1

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Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages

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Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion

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Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia

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Human astrocytomas and glioblastomas express monocyte chemoattractant protein-1 (MCP-1) in vivo and in vitro.

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Interferon-gamma stimulates the expression of CX3CL1/fractalkine in cultured human endothelial cells

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Neuronal expression of fractalkine in the presence and absence of inflammation.

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12 December 2020

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12 December 2020

Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.

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12 December 2020

Chemokines in neurological disease models: correlation between chemokine expression patterns and inflammatory pathology.

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12 December 2020

Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS

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12 December 2020

Human monocyte/macrophages activate by exposure to LPS overexpress NGF and NGF receptors

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12 December 2020

Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system

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12 December 2020

Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS.

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12 December 2020

Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia

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12 December 2020

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

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12 December 2020

Enhanced expression of fractalkine in HIV-1 associated dementia.

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12 December 2020

Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia?

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Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force

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Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease

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12 December 2020

Fractalkine receptor expression by T lymphocyte subpopulations and in vivo production of fractalkine in human

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12 December 2020

Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival

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12 December 2020

Nerve growth factor is an autocrine factor essential for the survival of macrophages infected with HIV

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12 December 2020

Unique role of the chemokine domain of fractalkine in cell capture. Kinetics of receptor dissociation correlate with cell adhesion

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12 December 2020

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses.

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12 December 2020

A continuing enigma: the role of cells of macrophage lineage in the development of HIV disease

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12 December 2020

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

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12 December 2020

Chemokines--chemotactic cytokines that mediate inflammation

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12 December 2020

Chemokine and chemokine receptor expression in the central nervous system

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12 December 2020

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

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12 December 2020

A new class of membrane-bound chemokine with a CX3C motif

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12 December 2020

Characterization of a novel binding site for the human immunodeficiency virus type 1 envelope protein gp120 on human fetal astrocytes

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12 December 2020

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12 December 2020

Fractalkine: a novel angiogenic chemokine in rheumatoid arthritis

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12 December 2020

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Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)

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Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel

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Ischemia-induced neuronal expression of the microglia attracting chemokine Secondary Lymphoid-tissue Chemokine (SLC).

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12 December 2020

Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection

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12 December 2020

Immunity, atherosclerosis and cardiovascular disease

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12 December 2020

Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1

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12 December 2020

Cellular localization of fractalkine at sites of inflammation: antigen-presenting cells in psoriasis express high levels of fractalkine

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12 December 2020

The neuropathogenesis of the AIDS dementia complex.

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12 December 2020

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage

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12 December 2020

Expression and regulation of chemokine receptors in human natural killer cells

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12 December 2020

Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades

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12 December 2020

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

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12 December 2020

Induction of the chemokines interleukin-8 and IP-10 by human immunodeficiency virus type 1 tat in astrocytes

1 reference

12 December 2020

Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

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12 December 2020

HIV-1-associated central nervous system dysfunction

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12 December 2020

Astrocytes express functional chemokine receptors

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12 December 2020

Neocortical damage during HIV infection

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12 December 2020

Chemokine receptors and mechanisms of cell death in HIV neuropathogenesis

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12 December 2020

Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

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12 December 2020

CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons.

1 reference

12 December 2020

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

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12 December 2020

Neuronal pattern correlates with the severity of human immunodeficiency virus-associated dementia complex. Usefulness of spatial pattern analysis in clinicopathological studies

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12 December 2020

Cytokine receptor CX3CR-1 and fractalkine: new factors in the atherosclerosis drama?

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12 December 2020

Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin

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12 December 2020

Primary macrophages infected by human immunodeficiency virus trigger CD95-mediated apoptosis of uninfected astrocytes

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12 December 2020

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

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12 December 2020

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

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12 December 2020

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

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12 December 2020

Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor

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12 December 2020

Regional CNS uptake of blood-borne nerve growth factor

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12 December 2020

The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo

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12 December 2020

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients

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12 December 2020

Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow

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12 December 2020

Upregulation of fractalkine in human crescentic glomerulonephritis

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12 December 2020

Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants.

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12 December 2020

Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms

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12 December 2020

Human chemokines: an update

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12 December 2020

The role of fractalkine in the recruitment of monocytes to the endothelium

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12 December 2020

Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons

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12 December 2020

Chemokines and receptors in HIV encephalitis

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12 December 2020

Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis

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12 December 2020

Chemokines and central nervous system disorders

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12 December 2020

Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

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12 December 2020

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

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12 December 2020

Interferon-gamma stimulates fractalkine expression in human bronchial epithelial cells and regulates mononuclear cell adherence

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12 December 2020

Deregulation of the expression of the fractalkine/fractalkine receptor complex in HIV-1-infected patients

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12 December 2020

Lipopolysaccharide-stimulated rat brain macrophages release NGF in vitro

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12 December 2020

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

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12 December 2020

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

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12 December 2020

Chemokine receptors and HIV.

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12 December 2020

Specificity of neurotrophin-3 determined by loss-of-function mutagenesis

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12 December 2020

Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation

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12 December 2020

The HIV-1 associated dementia complex: a metabolic encephalopathy fueled by viral replication in mononuclear phagocytes.

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12 December 2020

Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures

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12 December 2020

Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis

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12 December 2020

Phosphatidylinositol 3-kinase-dependent extracellular calcium influx is essential for CX(3)CR1-mediated activation of the mitogen-activated protein kinase cascade

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12 December 2020

Fractalkine expression in human renal inflammation

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12 December 2020

Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

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12 December 2020

Chemokines: a new classification system and their role in immunity

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12 December 2020

Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains

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12 December 2020

Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation

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12 December 2020

Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication

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12 December 2020

Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine

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12 December 2020

Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion

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12 December 2020

Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex.

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12 December 2020

Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia.

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12 December 2020

10.1080/13550280290100950

Identifiers

DOI

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Dimensions Publication ID

5 August 2017

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