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Immune intervention strategies for HIV-1 infection of humans in the SIV macaque model.
scientific article
Immune intervention strategies for HIV-1 infection of humans in the SIV macaque model
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Europe PubMed Central
PubMed publication ID
12477429
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
review article
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title
Immune intervention strategies for HIV-1 infection of humans in the SIV macaque model
(English)
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Europe PubMed Central
PubMed publication ID
12477429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
main subject
Macaca
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author
Zdeněk Hel
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3
1 reference
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Europe PubMed Central
PubMed publication ID
12477429
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
Elżbieta Tryniszewska
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4
1 reference
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Europe PubMed Central
PubMed publication ID
12477429
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15 December 2019
author name string
Genoveffa Franchini
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1
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PubMed publication ID
12477429
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
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15 December 2019
Janos Nacsa
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2
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Europe PubMed Central
PubMed publication ID
12477429
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15 December 2019
language of work or name
English
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publication date
1 December 2002
1 reference
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Europe PubMed Central
PubMed publication ID
12477429
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retrieved
15 December 2019
published in
Vaccine
1 reference
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Europe PubMed Central
PubMed publication ID
12477429
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retrieved
15 December 2019
volume
20 Suppl 4
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Europe PubMed Central
PubMed publication ID
12477429
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retrieved
15 December 2019
page(s)
A52-60
1 reference
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Europe PubMed Central
PubMed publication ID
12477429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
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ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency
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Failure to expand influenza and tetanus toxoid memory T cells in vitro correlates with disease course in SIV infected rhesus macaques.
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Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex
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CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine design and testing
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Phenotypic analysis of antigen-specific T lymphocytes
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Use of overlapping peptide mixtures as antigens for cytokine flow cytometry
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Neutralizing antibodies associated with viremia control in a subset of individuals after treatment of acute human immunodeficiency virus type 1 infection
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7 January 2021
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Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
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7 January 2021
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Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV.
1 reference
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7 January 2021
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The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia
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Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
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7 January 2021
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Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.
1 reference
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7 January 2021
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Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes
1 reference
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7 January 2021
based on heuristic
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Adoptive transfer of simian immunodeficiency virus (SIV) naïve autologous CD4(+) cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status
1 reference
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7 January 2021
based on heuristic
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HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
1 reference
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https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
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Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques
1 reference
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Crossref
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7 January 2021
based on heuristic
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Suppression of acute viremia by short-term postexposure prophylaxis of simian/human immunodeficiency virus SHIV-RT-infected monkeys with a novel reverse transcriptase inhibitor (GW420867) allows for development of potent antiviral immune responses r
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Early postinfection antiviral treatment reduces viral load and prevents CD4+ cell decline in HIV type 2-infected macaques
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment
1 reference
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https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Control of SIV rebound through structured treatment interruptions during early infection
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccination of macaques with long-standing SIVmac251 infection lowers the viral set point after cessation of antiretroviral therapy.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
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HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
1 reference
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https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: evidence for impaired CTL effector function
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of interleukin-2 and gamma interferon in human immunodeficiency virus disease
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional impairment of simian immunodeficiency virus-specific CD8+ T cells during the chronic phase of infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Skewed maturation of memory HIV-specific CD8 T lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIV preferentially infects HIV-specific CD4+ T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential S phase entry and apoptosis of CD4(+) T lymphocytes of HIV-1-infected patients after in vitro cultivation
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of phorbol myristate acetate on T cell colony formation, interleukin-2 (IL-2) receptor expression and IL-2 production by cells from patients at all stages of HIV infection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
gp41 envelope protein of human immunodeficiency virus induces interleukin (IL)-10 in monocytes, but not in B, T, or NK cells, leading to reduced IL-2 and interferon-gamma production
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory dysfunction of the interleukin-2 receptor during HIV infection and the impact of triple combination therapy
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Circulating levels and ex vivo production of beta-chemokines, interferon gamma, and interleukin 2 in advanced human immunodeficiency virus type 1 infection: the effect of protease inhibitor therapy.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of subcutaneous interleukin-2 therapy on CD4 subsets and in vitro cytokine production in HIV+ subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of IFN-g and IL-2 production by peripheral lymphocytes of HIV-exposed seronegative subjects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal intracellular IL-2 and interferon-gamma (IFN-gamma) production as HIV-1-assocated markers of immune dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons with </=250/microL CD4 T cells and undetectable plasma virus load
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of therapy with highly active anti-retroviral therapy (HAART) and IL-2 on CD4+ and CD8+ lymphocyte apoptosis in HIV+ patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subcutaneous administration of interleukin-2 in human immunodeficiency virus type 1-infected persons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic and virologic effects of subcutaneous interleukin 2 in combination with antiretroviral therapy: A randomized controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pooled analysis of 3 randomized, controlled trials of interleukin-2 therapy in adult human immunodeficiency virus type 1 disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 RNA levels in cerebrospinal fluid and plasma correlate with AIDS dementia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subcutaneous interleukin-2 in combination with anti-retroviral therapy for treatment of HIV-1-infected subjects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of subcutaneous and intravenous interleukin-2 in asymptomatic HIV-1 infection: a randomised controlled trial. ANRS 048 study group.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A randomized, controlled, phase II trial comparing escalating doses of subcutaneous interleukin-2 plus antiretrovirals versus antiretrovirals alone in human immunodeficiency virus-infected patients with CD4+ cell counts >/=350/mm3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A risk-benefit assessment of interleukin-2 as an adjunct to antiviral therapy in HIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison between subcutaneous and intravenous interleukin-2 treatment in HIV disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two low doses of tenofovir protect newborn macaques against oral simian immunodeficiency virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Response of naïve and memory CD8+ T cells to antigen stimulation in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Equivalent Immunogenicity of the Highly Attenuated Poxvirus-Based ALVAC-SIV and NYVAC-SIV Vaccine Candidates in SIVmac251-Infected Macaques
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): dependence on route of challenge exposure.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant canarypox vaccine-elicited CTL specific for dominant and subdominant simian immunodeficiency virus epitopes in rhesus monkeys
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased expression of IL-2 in central and effector CD4 memory cells during progression to AIDS in rhesus macaques
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel chimeric Rev, Tat, and Nef (Retanef) antigen as a component of an SIV/HIV vaccine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0264-410X%2802%2900388-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0264-410X(02)00388-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12477429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
PubMed publication ID
12477429
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12477429
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12477429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 December 2019
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