(Q35024115)

5 August 2017

title

The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPSc (English)

1 reference

5 August 2017

0 references

Eric M Norstrom

1

1 reference

5 August 2017

James A Mastrianni

series ordinal

2

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 September 2006

1 reference

5 August 2017

1 reference

5 August 2017

volume

80

1 reference

5 August 2017

issue

17

1 reference

5 August 2017

page(s)

8521-8529

1 reference

NMR structure of the bovine prion protein isolated from healthy calf brains

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Probing the instabilities in the dynamics of helical fragments from mouse PrPC.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Evidence for assembly of prions with left-handed beta-helices into trimers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Molecular and clinical classification of human prion disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Structural studies of the scrapie prion protein by electron crystallography

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Mutant prion proteins are partially retained in the endoplasmic reticulum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Evidence for the role of PrP(C) helix 1 in the hydrophilic seeding of prion aggregates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Eight prion strains have PrP(Sc) molecules with different conformations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

NMR structure of the mouse prion protein domain PrP(121-231)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Evidence for synthesis of scrapie prion proteins in the endocytic pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Chimeric prion protein expression in cultured cells and transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

Conformational change, aggregation and fibril formation induced by detergent treatments of cellular prion protein

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563859

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16912302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16912302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Three-dimensional NMR structure of a self-folding domain of the prion protein PrP(121–231)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16912302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.00366-06

1 reference

5 August 2017

1 reference

5 August 2017

1 reference