(Q35028520)

5 August 2017

1 reference

title

Sequential vs. parallel protein-folding mechanisms: experimental tests for complex folding reactions (English)

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5 August 2017

0 references

Louise A Wallace

1

1 reference

PubMed ID

12487994

5 August 2017

C Robert Matthews

series ordinal

2

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5 August 2017

1 December 2002

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5 August 2017

Biophysical Chemistry

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5 August 2017

101-102

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5 August 2017

113-131

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Principles that govern the folding of protein chains

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Protein folding: from the levinthal paradox to structure prediction

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Pathways of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

From Levinthal to pathways to funnels

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Protein Folding: A Perspective from Theory and Experiment.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Matching theory and experiment in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Is protein folding hierarchic? I. Local structure and peptide folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Is protein folding hierarchic? II. Folding intermediates and transition states

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The fundamentals of protein folding: bringing together theory and experiment

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Understanding protein folding via free-energy surfaces from theory and experiment

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Barriers in protein folding reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Navigating the folding routes

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Funnels, pathways, and the energy landscape of protein folding: a synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The energy landscape theory of protein folding: insights into folding mechanisms and scenarios

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

On-pathway versus off-pathway folding intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Competing unfolding pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Pathways for protein folding: is a new view needed?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Two-state models of protein folding kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Observation of strange kinetics in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

1 reference

7 January 2021

Kinetics of unfolding and refolding of proteins. I. Mathematical analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Intermediates in the folding reactions of small proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

How do small single-domain proteins fold?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Extremely rapid protein folding in the absence of intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Stability and folding properties of a model beta-sheet protein, Escherichia coli CspA.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

A quantitative treatment of the kinetics of the folding transition of ribonuclease A

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

A folding model of alpha-lactalbumin deduced from the three-state denaturation mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Understanding how proteins fold: the lysozyme story so far.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding of dihydrofolate reductase from Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Refolding of Escherichia coli dihydrofolate reductase: sequential formation of substrate binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

A reexamination of the folding mechanism of dihydrofolate reductase from Escherichia coli: verification and refinement of a four-channel model.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Development of nonpolar surfaces in the folding of Escherichia coli dihydrofolate reductase detected by 1-anilinonaphthalene-8-sulfonate binding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Early intermediates in the folding of dihydrofolate reductase from Escherichia coli detected by hydrogen exchange and NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Characterization of the slow steps in the folding of the alpha subunit of tryptophan synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding mechanism of the alpha-subunit of tryptophan synthase, an alpha/beta barrel protein: global analysis highlights the interconversion of multiple native, intermediate, and unfolded forms through parallel channels

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Identifying the structural boundaries of independent folding domains in the alpha subunit of tryptophan synthase, a beta/alpha barrel protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding and stability of trp aporepressor from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Structure and stability of an early folding intermediate of Escherichia coli trp aporepressor measured by far-UV stopped-flow circular dichroism and 8-anilino-1-naphthalene sulfonate binding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Characterization of the slow folding reactions of trp aporepressor from Escherichia coli by mutational analysis of prolines and catalysis by a peptidyl-prolyl isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Mechanism of folding of the dimeric core domain of Escherichia coli trp repressor: a nearly diffusion-limited reaction leads to the formation of an on-pathway dimeric intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The barriers in the bimolecular and unimolecular folding reactions of the dimeric core domain of Escherichia coli Trp repressor are dominated by enthalpic contributions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Rough energy landscapes in protein folding: dimeric E. coli Trp repressor folds through three parallel channels

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic mechanism of luciferase subunit folding and assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Three-state model for lysozyme folding: triangular folding mechanism with an energetically trapped intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Apoflavodoxin folding mechanism: an alpha/beta protein with an essentially off-pathway intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic mechanisms of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Effect of point mutations on the folding of globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Use of multiple spectroscopic methods to monitor equilibrium unfolding of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

A continuous-flow capillary mixing method to monitor reactions on the microsecond time scale.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Methods for exploring early events in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Laser temperature jump study of the helix<==>coil kinetics of an alanine peptide interpreted with a 'kinetic zipper' model

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Microsecond folding of the cold shock protein measured by a pressure-jump technique

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Denatured states of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Analysis of numerical methods for computer simulation of kinetic processes: development of KINSIM--a flexible, portable system.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

New PC versions of the kinetic-simulation and fitting programs, KINSIM and FITSIM.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Slow refolding kinetics in yeast iso-2 cytochrome c.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Multiple intermediates and transition states during protein unfolding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Mechanism of folding of ribonuclease A. Slow refolding is a sequential reaction via structural intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Coupled kinetic traps in cytochrome c folding: His-heme misligation and proline isomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Specific intermediates in the folding reactions of small proteins and the mechanism of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic role of early intermediates in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

An essential intermediate in the folding of dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Highly divergent dihydrofolate reductases conserve complex folding mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Evidence for an obligatory intermediate in the folding of interleukin-1 beta

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Structural characterization of protein folding intermediates by proton magnetic resonance and hydrogen exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Hydrogen exchange studies of protein structure

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Hydrogen exchange: the modern legacy of Linderstrøm-Lang

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Protein folding intermediates and pathways studied by hydrogen exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetics of folding of the all-beta sheet protein interleukin-1 beta

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetics of ligand binding to dihydrofolate reductase: binary complex formation with NADPH and coenzyme analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetics of ternary complex formation between dihydrofolate reductase, coenzyme, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Evaluation of the importance of hydrophobic interactions in drug binding to dihydrofolate reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Native Escherichia coli and murine dihydrofolate reductases contain late-folding non-native structures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Multistate equilibrium unfolding of Escherichia coli dihydrofolate reductase: thermodynamic and spectroscopic description of the native, intermediate, and unfolded ensembles

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Effect of a single amino acid substitution on the folding of the alpha subunit of tryptophan synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Proline isomerization and the slow folding reactions of the alpha subunit of tryptophan synthase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Characterization of a slow folding reaction for the alpha subunit of tryptophan synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Multiple replacements at position 211 in the alpha subunit of tryptophan synthase as a probe of the folding unit association reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Molecular dissection of the folding mechanism of the alpha subunit of tryptophan synthase: an amino-terminal autonomous folding unit controls several rate-limiting steps in the folding of a single domain protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Unfolding-refolding kinetics of the tryptophan synthase alpha subunit by CD and fluorescence measurements.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Equilibrium and kinetic analyses of unfolding and refolding for the conserved proline mutants of tryptophan synthase alpha subunit.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Urea-induced unfolding of the alpha subunit of tryptophan synthase: evidence for a multistate process

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The progressive development of structure and stability during the equilibrium folding of the alpha subunit of tryptophan synthase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Molecular collapse: the rate-limiting step in two-state cytochrome c folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

A kinetic explanation for the rearrangement pathway of BPTI folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Transient intermediates in the folding of dihydrofolate reductase as detected by far-ultraviolet circular dichroism spectroscopy.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Localized, stereochemically sensitive hydrophobic packing in an early folding intermediate of dihydrofolate reductase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The folding mechanism of barstar: evidence for multiple pathways and multiple intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

pH-jump-induced folding and unfolding studies of barstar: evidence for multiple folding and unfolding pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The refolding of cis- and trans-peptidylprolyl isomers of barstar

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic traps in lysozyme folding

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The X-Pro peptide bond as an nmr probe for conformational studies of flexible linear peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding of ribonuclease T1. 1. Existence of multiple unfolded states created by proline isomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic analysis of the unfolding and refolding of ribonuclease T1 by a stopped-flow double-mixing technique

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The Pro117 to glycine mutation of staphylococcal nuclease simplifies the unfolding-folding kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Effects of guanidine hydrochloride on the refolding kinetics of denatured thioredoxin.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding and unfolding kinetics of the proline-to-alanine mutants of bovine pancreatic ribonuclease A

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic and thermodynamic studies of the folding/unfolding of a tryptophan-containing mutant of ribonuclease A

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Fast-folding and slow-folding forms of unfolded proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

A native-like intermediate on the ribonuclease A folding pathway. 2. Comparison of its properties to native ribonuclease A

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Methotrexate, a high-affinity pseudosubstrate of dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Demonstration by NMR of folding domains in lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Detection and characterization of a folding intermediate in barnase by NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Identification and characterization of the direct folding process of hen egg-white lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Early folding intermediate of ribonuclease A.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Cis proline mutants of ribonuclease A. II. Elimination of the slow‐folding forms by mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Nature of the unfolded state of ribonuclease A: effect of cis-trans X-Pro peptide bond isomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic folding and cis/trans prolyl isomerization of staphylococcal nuclease. A study by stopped-flow absorption, stopped-flow circular dichroism, and molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The role of ligand binding in the kinetic folding mechanism of human p21(H-ras) protein

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic mechanism of cytochrome c folding: involvement of the heme and its ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Kinetic role of a meta-stable native-like two-disulphide species in the folding transition of bovine pancreatic trypsin inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Structure of a protein in a kinetic trap

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding and association of the antibody domain CH3: prolyl isomerization preceeds dimerization

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

Folding and assembly of dimeric human glutathione transferase A1-1

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

The final stages of folding of the membrane protein bacteriorhodopsin occur by kinetically indistinguishable parallel folding paths that are mediated by pH 1 1Edited by A. R. Fersht

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2802%2900155-2

7 January 2021

10.1016/S0301-4622(02)00155-2

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12487994